1.Primary evaluation on the effect of a herbal extract named Thuong doc cao for early skin lesions in cancer patients who were receiving COBALT-60 radiotherapy
Journal of Practical Medicine 2002;435(11):22-23
Thuong doc cao (TDC) is a Vietnamese traditional herbal formulation made from heat-eradicated herb medications. 100 randomly selected patients with cancers who were treating by Cobalt-60 radiotherapy were divided into two groups. Group 1 included 50 patients was served as intervention group, and the other served as control. Group 1 received TDC application and the other applied by the solution of 0.9% sodium. Results of radiotherapy in two groups, the effect of TDC on treatment and on self-reported feeling of patients were evaluated. It was found that TDC reduced the severity of skin lesions in irradiated areas. The patients could receive the expected irradiation doses. TDC provided the ease and cool feels, reduced the stretched and hot feels in irradiated areas. There was not any case of allergy or adverse effects.
Skin
;
Neoplasms
2.Malaria situation of unorganized people in a vilillage of the highland province in EaRot, Cu Pui, Khong Bong, DakLak province
Journal of Malaria and parasite diseases Control 2004;0(3):25-30
Studies of 805 samples until 10/2004 show that the malaria prevalence was high in the first 5 months in 2003, among 7 deaths were unorganized migrants. They contract malaria all year round, especially in the beginning of the year with the highest of 11.96% in February. The density of maralia parasite (+) was high in months at the beginning and end of the year such as January, April and October with the density in the first month of 2.92%. Spleenomegaly was mostly seen in age 5-14 with 3.17% and mostly in grade I and II (97.8%). Spleenomegaly grade III and IV is predominated in over 14 years old group (60%). Vectors at the first three months of the year were high and various in species in accordance with the malaria prevalence. An. dirus and An. minimus as the two main vectors of transmitting were present in almost of the year both house inside and outside, which is the cause for the transmission
Malaria
;
Epidemiology
3.The efficacy of laparoscopic surgery for patients with tubal factor infertility
Ho Chi Minh city Medical Association 2005;10(2):73-76
Survey 140 patients with tubal factor infertility at Tu Du Hospital from 2002 to 2003. Intrauterine pregnancy rate was 19.3% and ectopic pregnancy rate was 9.3%. Patient’s age is one of factors influencing the outcome of laparoscopic surgery. The elder patients are, the lower pregnancy rate they get (for patients over 35 years old, pregnancy rate is as low as 4%). The level of tubal damage and adhesion are also influencing factors for rate of intrauterine pregnancy. The more severe damage and adhesion patients had, the lower pregnancy rate they get. The prognosis of tubal factor infertility was highly associated with the level of tubal damage and patient’s age. Laparoscopic surgery for tubal obstruction is only effective for cases with mild or moderate lesion. For elder cases over 35 years old or severe tubal damage, IVF-ET should be indicated
Infertility
;
Laparoscopy
;
Sterilization, Tubal
4.Some techniques of detection of type B Haemophilus influenza in the diagnosis of meningitis due to type B H. influenza
Journal of Practical Medicine 2003;425(5):56-59
Some techniques of detection of Hib were compared, including classic techniques such as bacterial culture and modern techniques such as PCR method. The results were as follows: 21% (+) culture with Hib compared to the total of clinically diagnosed cases, Hib-latex agglutination with 95% sensitivity and 99.6% specificity, counter immunophoresis assay to detect Hib by 97% sensitivity and 100% specificity. PCR increased the number of positive cases of Hib meningitis by 42.8% compared to culture alone. Blood culture gave a highly significant value to diagnose (51% Hib-possitive culture)
Haemophilus influenza type b
;
Meningitis
;
methods
;
diagnosis
5.Therapeutic approaches for uterine fibroma
Ho Chi Minh city Medical Association 2005;10(5):293-300
There is about 30% of women experienced uterine fibroma and most of them needn’t treatment. For symptomatic women, various medical treatments were more and more extensive. Surgical treatments were indicated depending on many factors and individual patient. Besides traditional therapies (myomectomy, hysteroscopic myomectomy, uterine endoscopy, etc), there were more and more new techniques such as uterine artery embolization. This technique is relative new and minimal invasive of management, but it still needs further research
Leiomyoma
;
Therapeutics
6.Investigation of lactic acid bacteria’s abilities of transfering the anti-antibiotic gene by conjugation
Journal Ho Chi Minh Medical 2005;9(1):35-38
Isolate, purify, and identify bacteria from probiotic supplement. Results: 5 strains of lactic bacteria were determined, including: Steptococus feacalis; Streptococcus lactic; Bifidobacterium bifidum; Lactobaccillus acidophilus; Lactobacillus casei. Study the sensitivity of these bacteria with antibiotics, results showed that these bacteria were resistant to many antibiotics, especially oral antibiotics. Conjugative trial between Streptoccocus feacalis, Streptococus lactic, Bifidobacterium bifidum, lactobacillus acidophilus casei and E.coli K12, and conjugative trial of lactic bacteria together showed negative results. Therefore, probiotic product contained many lactic bacteria can be used concomitant with some oral antibiotics to prevent or treat digestive disorders
Anti-Bacterial Agents
;
Bacteria
7.On occasion of 3 cases of the feminized testicle
Journal of Medical Research 1999;9(1):32-35
The classification, diagnosis and management of the feminized testicle were implemented in the institute of mother and infant protection and care during 1998-1999 showed that the feminized testicle only found after the puberty age with the reasons of the primary menostasis or abnormality of the external genitalia. The clinical condition of 3 patients were typical. The hormone replacement therapy was used after the removal of testicle and reconstruction of the external genitalia.
Testis
;
Case Reports [Publication Type]
8.Clinical, laboratory characteristics and CT scanning images of pleural effusion due to primary lung cancer
Journal of Medical Research 2004;27(1):75-81
A prospective study was performed on 50 in-patients (62% male, 38% female) with pleural effusion due to primary lung cancer and pleural cancer at Bach Mai Hospital from October 2002 to November 2003, mean age of 57.9 14.4 year old. In 70% of patients the disease developed for more than 4 weeks. Common clinical signs were chest pain 92%, dysapnea 68%, prolonged dry cough 52%, hemoptypsy 16%. The syndrome of 3 reduces occured in 100% of cases. Effusion on right side is 60% vs 30% on left side. In 4%, there was bilateral effusion. Cancer cells notified in 30% of pleural fluid, and in 58.1% of pleural biopsies
Diagnosis
;
Tomography, X-Ray Computed
;
Pleural Effusion
;
Lung Neoplasms
9.Molecular approach for rapid diagnostic kit to detect Yersinia pestis from infected soil, water sample
Journal of Medical Research 2005;38(5):17-22
Yersinia pestis is the cause for the acute infection and may be chosen for biological terrorism. Rapid diagnosis of this agent from infected soil - water is essential. Y. pestis habours 3 specific plasmids providing virulent factors to the bacterium. Objectives: (1) Testing the sensitivity and accurateness of PCR for Y. pestis. (2) Carrying out PCR using total genomic DNA serially diluted as a template. (3) Undertaking PCR on artificical experimentation by diluting Y. pestis in soil water as samples to test PCR based fast diagnostic approach. Methods: Yersinia pestis (inactivated) was used. Genomic DNA was extracted by DNeasy kit (Qiagen Inc). Using primer - pairs PLAF - PLAR (binding on pia gene of plasmid pPCP1) a specific product of PCR was 480 bp. After determination of the PCR sensitivity, a molecular based diagnostic kit was developed. Sensitivity and specificity of this kit was tested by PCR using diluted genomic DNA and bacterium itself; and mix of these templates in water and soil as samples. Results: With the diluted genomic DNA, it was successful to obtain specific PCR with 0.6ng template, which is equal to a single bacterium. Additionally, successful PCR amplification was obtained using the whole bacterium (without extraction of genomic DNA) and diluted quantity ranging from 101 to 102. Based on these results, the bacterium was artificially diluted with sample of soil - water as a natural isolate for PCR amplification. Conclusions: Evidently, approach for PCR-based diagnostic kit was successfully carried out from any template including soil - water samples with high fidelity, using the pia gene genetic marker of pPCR of Y. pestis.
Yersinia
;
Water
;
Soil
10.Application of Pulsed field gel electrophoresis (PFGE) for typing sudy base on Haemophilus influenzae molecular
Journal of Preventive Medicine 2005;15(1):23-28
The study was conducted to compare the molecular differences of Haemophilus influenzae type b (Hib) strains causing meningitis in young children with H. influenzae strains causing acute upper respiratory tract infection, 44 Hib strains and 37 H. influenzae strains were analysed by pulsed field gel electrophoresis (PFGE) with SmaI restriction enzyme. The results: 44 Hib strains were mainly distributed into 4 DNA restriction patterns (PFGE patterns) whereas 37 H. influenzae strains were distributed into 22 patterns and 81% of them were not encapsulated. The genome of Hib strains causing bacterial meningitis showed less variation than that of H. influenzae causing acute upper respiratory infection. PFGE is a useful tool for epidemiological research.
Haemophilus influenza
;
Child