Objective To investigate anesthesia efficacy and safety between two drugs joint propofol intrave-nous anesthesia for colonoscopy,to provide reference for clinical treatment.Methods 120 routine colonoscopy patients were selected,they were randomly divided into control group and observation group,60 cases in each group. Patients of the control group were given ketamine and propofol before examination.Patients in the observation group were given fentanyl and propofol for intravenous anesthesia before the examination.The arterial pressure MAP,heart rate,HR,pulse oximetry SpO2 ,recovery time,time away from the hospital,anesthetic effects and adverse reactions were compared between the two groups.Results Anesthesia excellent rate in the observation group was 86.67%,that was 85.00% in the control group,the difference was not significant (χ2 =0.984,P =0.114).In the observation group,the recovery time and time away from the hospital were (7.44 ±1.24)min,(19.11 ±2.67)min,which were significantly shorter than those in the control group,the differences were statistically significant (t =5.847,P =0.004;t =6.922,P =0.001).The MAP,SpO2,HR at different time points showed statistically significant differences between the two groups(P >0.05).The incidence rate of adverse reactions in the observation group was 21.67%, that in the control group was 36.67%,the difference was not statistically significant (χ2 =5.665,P =0.007). Conclusion Fentanyl and propofol for intravenous anesthesia in colonoscopy has good anesthetic effect and good safety,which is worthy of clinical application.

ObjectiveTo evaluate the application effect of homemade visible stomach tube guiding device in patients with gastric canal implantation under general anesthesia.MethodsFrom January to December 2015,90 patients who would undergo gastrointestinal or hepatobiliary surgery under general anesthesia with indwelling gastric tube were selected as the research object by purpose sampling method. 90 cases were divided into group A (conventional catheter),group B (guidewire guided) and group C (homemade visible stomach tube guiding device guided),with 30 cases in each group. All patients received gastric canal implantation immediately after endotracheal intubation under general anesthesia. We recorded the time of one-time successful gastric tube implantation,the times of implantation,the number of successful cases that implanted at a time,the total number of cases with successful implantation and the number of cases with throat mucosal injury.ResultsThe intubation time of group A and group B were longer than that of group C (P<0.05). The time in group A was the longest. Only 10 cases in group A were successful implanted in one time,19 cases in group B were successfully implanted in one time,and all the cases in group C were successfully implanted in one time. The one-time success rate of gastric canal implantation of group C (100.0%) was higher than that of group A (33.3%) and group B (63.3%) (P<0.05). The total success rate of gastric canal implantation of group A (53.3%) was lower than that of group B (90.0%) and group C (100%) (P<0.05). The incidence of throat mucosal injury of group C (3.3%) was lower than that of group A (33.3%) and group B (26.7%) (P<0.05).ConclusionsThe homemade visible stomach tube guiding device can quickly improve the one-time success rate of gastric canal implantation in patients under general anesthesia,reduce the time of implantation and decrease the incidence of throat mucosal injury.