The objectives of this study were to investigate the effects of Hericium erinaceum (Yamabusitake) and Grifola frondosa (Maiteke) on the proliferation for EL4-tumor and immunoregulatory function by flow cytometory.
It was found that Yamabushitake and Maitake tend to inhibit the proliferation of EL4-tumor individually. In the flow cytometory analysis, Maitake-treatment showed the preserve effect against the depression effect by bearing EL4-tumor on cytotoxic T cell and NK-cell from spleen cell. This effect was shown more clear in the group of mixture Yamabusitake and Maitake.