1. Evaluation of fluid intake and its relationship between preterm delivery in pregnant women
Tergel N ; Tumenjargal T ; Enerel B ; Anand B ; Odkhuu E
Innovation 2014;8(3):38-40
BACKGROUNDAccording to WHO statistics of 2013, daily 371,124[1] births, annually 135.5 million [1] births occur worldwide which tends to increase in the following years. In Mongolia, studies that evaluaterelationship between fluid intakes of pregnant women and preterm delivery risk have not been conducted so far to our knowledge. Thus, we aimed to determine this relationship by evaluating first and second trimester fluid intakesof pregnant women in Mongolia.METHODS35 and above years old pregnant women of 24-32 gestational weeks have been included in the study where body measurements and fluid intake were collected via questionnaireand examination.RESULTSWhen we studied the relationship between average fluid intake and preterm delivery risk, having inadequate fluid intake in the first trimester increased the risk of preterm delivery by 5.98 (CI95% 0.89-40.08, p<0.01) fold whereas having inadequate fluid intake in the second trimester increased the risk of preterm delivery by 4.03 (CI 95% 1.06-15.21, p<0.01) foldrespectively.CONCLUSIONSOur results show that low fluid intake in first and second gestational trimesters results in increased risk of preterm delivery significantly in Mongolia.
2.The results of the test for assessing the manifestation of side effects of antipsychotic drugs, which are characterized by abnormal involuntary movements
Khishigsuren Z ; Tergel Kh ; Khongorzul E ; Elik M
Mongolian Journal of Health Sciences 2025;85(1):125-129
Background:
According to WHO research, there are approximately 24 million people living with schizophrenia worldwide and schizophrenia is characterized by a combination of psychotic and non-psychotic symptoms. Since the cause of
the disease is not fully understood, antipsychotic medications are used as symptomatic treatment. According to the 2022
statistics of the NCMH, 718 people with schizophrenia are being treated under active surveillance in Mongolia. The reason for conducting this study is that the manifestation of drug side effects resulting movement disorders in patients with
schizophrenia, which has not been studied in Mongolia.
Aim:
To investigate the relationship between adherence of medication regimen and abnormal involuntary movements in
patients with schizophrenia.
Materials and Method:
The study was conducted using a descriptive method, cross-sectional design, purposive sampling with the questionnaire and standardized tests. Ethical approval for this study was approved by the NCMH (№3/77
30th of January, 2023) and Research Ethics Review Committee of MNUMS (№2023/3-02). Each participant was asked to
complete 5 groups of 36 questionnaires, and standard tests were used to assess patients’ adherence to medication regimens
(Morisky scale) and abnormal involuntary movement scale (AIMS). The study was conducted between March and August
2023, and the results were summarized and analyzed using STATA 14 software.
Results:
The study included 209 patients with schizophrenia, aged 18-79 years, of whom 47.4% (n=99) were male
and 52.6% (n=110) were female (p=0.21). Of the participants, 28.2% (n=59) had less than secondary education, 76.5%
(n=160) were unmarried, and 85.2% (n=178) had a disability due to mental health. 32.5% (n=68) of the patients with
schizophrenia in the study used a combination of typical and atypical medications, and the most commonly used antipsychotic drugs were haloperidol (30.6%), chlorpromazine (26.8%), levomepromazine (25.8%), risperidone (24.4%),
and quetiapine (21.1%). 1.4% (n=3) of the patients had good, 52.6% (n=110) had moderate, and 45.9% (n=96) had poor
adherence to the medication regimen (Cronbach’s α=0.781). However, according to the results of the test for assessing
abnormal involuntary that are performed without self-control, 49.76% (n=104) responded that they felt more sensitive to
facial and oral movements, and 44.5% (n=93) to limb movements. The patients’ adherence to the medication regimen was
statistically significant with facial and oral movements (n=104; p=0.036) and general body movement disorders (n=94;
p=0.05).
Conclusion
32.5% of patients with schizophrenia were taking typical and atypical antipsychotics, and 45.9% had poor
adherence to medication regimens and were more likely to exhibit clinical forms of abnormal involuntary movements,
including facial (p=0.036) and general movement disorders (p=0.05).
3.Results of evaluation memory changes in epilepsy patients
Tergel Kh ; Sarina SU ; Tovuudorj A ; Khishigsuren Z
Mongolian Journal of Health Sciences 2025;85(1):214-218
Background:
Memory is a complex combination of the activities of fixation, keeping and recalling information, which
is manifested by quantitative and qualitative changes due to organic mental disorders. Epilepsy is a disorder with neurological and mental symptoms, and depending on the course of the disease, adherence to medication regimen, and the
frequency of seizures, memory can decrease leading to partial or complete dementia. Therefore, we conduct this study by
Luria A.Ya’s assessment evaluating memory’s changes, such as mechanic memory.
Aim:
The aim of the study is to evaluate the memory changes in patients with epilepsy using standart questionnaire.
Materials and Methods:
The study was a hospital-based, descriptive, cross-sectional design, using a questionnaire survey method, and using a standard 10-word memorizing test. The study was conducted in NCMH from 1st of July to 1st of
August of 2023 and ethical approval for this study was approved by the NCMH (3/603 14th of June, 2023) and Research
Ethics Review Committee of MNUMS (2023/3-08 16th of June 2023). Collected data statistics were created by graphics
and tables on Microsoft Word and Microsoft Excel programs and were analyzed in SPSS 21.0 software.
Results:
The study included 30 patients, 19 (62.5%) men and 11 (36.3%) women, aged 25-59, with a disease duration
of 4-59 years. In 60% of cases cause of the disease was brain injury, n=18 had less than secondary education, and n=26
(86.6%) had defined with disability. 73.2% of the study participants fell 2-3 times a week, 73.3% did not take medication
as prescribed, and 56.7% did not follow the medication regimen. The results of the 10-word memorizing test showed that
1-9 words were said more often in each repetition, with an average value of 3.2-3.9 for each repetition, and the frequency
of the extra words was 0.8. When examining whether the word memorizing test scores depended on the duration of the
illness, the number of words recalled by patients with illness lasting up to 59 years was 1-3, indicating that the longer the
illness lasted, the lower memory.
Conclusion
73.3% of patients do not take medications as prescribed by their doctor (p=0.35), 56.7% do not follow
the medication regimen, the average value of the mechanical memory test is 3.2-3.9, and the results show that memory
decreases with the duration of the disease, indicating that there are many reasons for the decrease in patients’ memory.
4.Review of pharmacological studies of Mongolian medicine Usnea longissima Ach
Xiaojing Han ; Bolor ; Tergel ; Laxinamujila ; Meirong Bai
Mongolian Pharmacy and Pharmacology 2020;16(1):18-22
Introduction:
Lichen is a stable symbiotic complex formed by fungi and symbiotic algae.
There are many kinds of lichens, which are cold and drought resistant, and have strong adaptability
to the environment. Lichens can grow and reproduce in places where other organisms are difficult
to survive. Apart from their ecological importance, they have become important natural medicinal
resources due to the production of a large number of unique secondary metabolites (depsides, depsidones, dibenzofurans, pulvinic acid derivatives) and pigments (anthraquinones, napthoquinones,
and xanthones) which can act as biomarkers as well as bioactive compounds. Usnea longissima
Ach. is a hanging hair lichen, that grows circumpolar in high humidity inland areas and coastal forests of Europe, Asia, and North America. This lichen has been used therapeutically for centuries
in Mongolian traditional systems of medicine for its analgesic, cardiotonic, stomachic, and wound
healing properties. Recently, many scholars have studied the chemical constituents and biological
activities of Usnea longissima Ach and its related varieties, and obtained gratifying results. Previous studies on its chemical constituents have resulted in isolation of several bioactive secondary
metabolites which include monosubstituted phenyls, depsides, anthraquinones, dibenzofuran derivatives, and terpenoids. In order to understand the clinical application and devote to the deeper
scientific research and development, the pharmacological literature of Usnea longissima Ach was
sorted out in this study.
Methods:
Collect and sort out the modern periodical literature and the related pharmacological
studies of Usnea longissima Ach in academic websites.
Result and Conclusion
The pharmacological studies of Mongolian medicine Usnea longissima Ach were studied in this paper. Usnea longissima Ach has a long history of medicinal use, which is recorded in the traditional medical materials of Tibetan, Mongolian, Uygurs, Tai and other ethnic minorities, as well as traditional Chinese medicine. According to the records, different nationalities in different countries have their own traditional medical theories as the basis for the diagnosis and treatment of different diseases. Previous studies on its chemical constituents have resulted in isolation of several bioactive secondary metabolites which include monosubstituted phenyls, depsides, anthraquinones, dibenzofuran derivatives, and terpenoids. The Usnea longissima Ach tastes bitter and it has the function of anti-bacterial, antioxidant, anti-cancer and detoxification effects. But it requires further study such as extract, isolate, and analyze the more chemical ingredients and its pharmacological activity.