Objective To explore the application of three dimensionally structured nursing management mode in the treatment of multiple trauma patients. Methods One hundred and eighty-seven patients with multiple injuries in the emergency department of our hospital from January to December 2010 were set up as the control group, and the traditional method was used in the group. Another 189 patients with multiple injuries from January to December 2011 were set as the observation group , in which the three dimensionally structured nursing management mode was used. The two groups were compared in terms of success rate. Result The success rates of the observation group and the control group were 85.7%(162/189) and 71.7%(134/187), respectively. The difference between the two group was statistically significant (Χ2=19.19,P<0.01). Conclusion The implementation of the three-dimensionally structured nursing management model can improve the comprehensive ability of emergency treatment and then improve the success rate of rescuing emergency patients.