Basic science and experimental research on stem cells has
increased exponentially in the last decade. Our present
knowledge about stem cell biology is better than ever before.
This new paradigm shift in research has been reflected in the
field of orthopaedic surgery. Various experimental models
have suggested a potential application of stem cells for
different orthopaedic conditions, and early clinical results of
stem cell use have been encouraging. These cells can be
easily isolated, processed and made available for clinical use.
From healing of bone defects caused by trauma, tumor or
infection to cartilage defects, nerve, tendon and ligament
healing, stem cell use has the potential to revolutionize
orthopaedic practice. The purpose of this article is to orient a
general orthopaedic surgeon towards the current use and
clinical applications of stem cell based therapy in
orthopaedics and to provide a complete overview of the
clinical advances in this field.
Stem Cells