Objective To test the serum albumin level in patients having the peritoneal dialysis,and investigate its relationship with C-reactive protein(CRP)level or other inflammatory complications. Methods Sixty patients having peritoneal dialysis treatment were divided into two groups based on the serum albumin(ALB)level,patients had normal ALB level were included into group A,while the patients with serum hypoproteinemia were included into group B. The serum level of CRP,transferin(TF)and nutritional status were compared between two groups,and their relationship with clinical complications were evaluated. Results The serum CRP level in patients of group B(8.40 ± 1.32)mg/L was significantly higher than group A(2. 14 ±0.87)mg/L(P ＜0. 01). Patients from group B had more inflammation complications,such as peritonitis(6. 7%),pneumonia(13. 3%),cardiovascular disease(16.7%). Conclusions The continuous ambulatory peritoneal dialysis patients accompanied with hypoproteinemia are more likely to have inflammation complications and cardiovascular diseases,which should cause more attention on their malnutrition-inflammation- CVD(MIA)syndrome diagnosis and treatment.

Metabonomics is the branch of science concerned with the quantitative understandings of the metabolite complement of integrated living systems and its dynamic responses to the changes of both endogenous factors (such as physiology and development)and exogenous factors (such as environmental factors and xenobiotics). As a holistic approach, metabonomics detects, quantifies and catalogues the time related metabolic processes of an integrated biological system, ultimately, relates such processes to the trajectories of the pathophysiological events. Ever since its birth in 1999, metabonomics has already been described in more than 800 scientific papers and half dozen patents, amongst which almost 700 papers were experimental articles. Now, metabonomics has been established as an extremely powerful analytical tool and hence found successful applications in many research areas including molecular pathology and physiology, drug efficacy and toxicity, gene modifications and functional genomics, and environmental sciences. This holistic approach has thus become an important part of systems biology and has now evolved to be a unique part in global systems biology. The essence of metabonomics and some of the present applications were reviewed to illustrate the rapid development of this extremely exciting new frontier.

Hypcrlipidemia is one of etiological factors of pancreatitis,of which the genesis has somewhat speci ficity.This article reviews hyperlipidemia related pancreatitis about its conception,etiology,classification,pathogene sis.specific clinical manifestation as well as diagnosis and treatment.

Objective To explore the nutritional status of vitamin D among healthy adults lived in Fuling district of Chongqing .Methods A total of 718 healthy adults aged 23-90 years old undergoing the physical examination in the physical ex‐amination center of our hospital from March 2012 to December 2013 were selected and divided into the 23-44 years old group and the ≥45 years old group .The tandem mass spectrometer was adopted to detect the level of serum 25(OH) vitamin D for evaluating the nutritional status of vitamin D .Results The proportions of lack ,insufficiency ,normal and excess of vitamin D in the 23 -44 years old group were 80 .79% ,19 .21% ,0% and 0% respectively ;which in the ≥45 years old group were 77 .91% ,18 .20% ,3 . 89% and 0% respectively .The average level of serum 25(OH) vitamin D in 23-44 years old group was lower than that in the ≥45 years old group ,the difference was statistically significant (P=0 .002 ,t=1 .98) .In these two groups ,the difference in serum 25 (OH) vitamin D level between males and females had no statistical significance (P>0 .05) .Conclusion The healthy adults in Ful‐ing district are lack of vitamin D in different degrees .

Objective To evaluate the effect of community nurse training in peripherally inserted central catheter (PICC) on community nursing quality of tumour patients with indwelled PICC during the intermission of chemotherapy.Methods A prospective study was performed with a total of 220 patients with esophageal or lung cancer enrolled from September 2011 to March 2013 in the Department of Cardiothoracic Surgery,the First Affiliated Hospital of Chongqing Medical University.The 220 patients included 174 males (79.1％) and 46 females (20.9％),at the age of (61.1 ±9.0) years.With the start of community nurse training as the cut-off line,the patients were divided into pre-training group (n =119) and post-training group (n =101).PICC-related complications and patient satisfaction were compared between the 2 groups.Results The overall PICC-related complication rate was 20.9％ (46/220) during community nursing,including,in the order of declining incidence,infection (7.2％,16/220),and venous thrombosis (4.5％,10/220),catheter occlusion (3.6％,8/220),catheter dropping (2.7％,6/220),and leaking/damage (2.7％,6/220).The total complication rate and incidence of infection in the post-training group were both significantly lower than those in the pre-training group (14.9％ vs.26.1％,P =0.047 ; 3.0％ vs.10.9％,P =0.035),and patient satisfaction (including satisfaction for answers to questions about PICC,feelings about PICC indwelling and PICC position,and overall satisfaction) was significantly higher than in the pre-training group (P =0.003,P =0.011,P =0.001).Conclusion Community nurse training programmes have positive effects on improving PICC-related nursing and patient satisfaction in cancer patients with PICC indwelling during intermissions of chemotherapy.

Objective To determine and evaluate the method of localization of anal verge by mutislice spiral CT. To provide an imaging reference for operative guidance of low-rectal cancer. Methods Forty eight consecutive adult patients suspected of abnormalities other than rectal disease were evaluated with abdominal and pelvic CT scans since August, 2009. They were divided into two groups based on sex and age. There were 23 men and 25 women. The ages of young group were 28 to 50 years and the average age was 41 years. The ages of elderly group were 52 to 81 years and the average age was 64 years. A small cotton ball dipped with contrast media was put at the anal verge as a marker and CT scans were performed with 64-slice spiral CT scanner. The distances between the cotton balls and the lower margin of the pubis combination (La), the lower margin of the 5th sacral vertebra (Lb), the inferior aperture of minor pelvis(Lc) and the lower margin of the basement of external anal sphincter (Ld) were measured on the midsagittal images obtained by MPR. The averages, the standard deviations(s), the 95% and 80% confidence intervals of La, Lb, Lc and Ld were calculated. We took the intervals of ± 1.96 s or ± 1.28 s ＜ 5 mm as the standard of meeting the clinical requirement. The distances meeting the clinical requirement between different sex groups or age groups were compared with t test. Results The Ld was (9.8 ± 1.2) mm, ofwhich intervals of ± 1.96 s and ± 1.28 s were 4. 8 mm and 3.0 mm respectively, meeting the clinical need.This distance was also measured conveniently. There were no significant differences ( P ＞ 0.05 ) between two different sex groups [ male group, ( 10.0 ± 1.2) mm], female group, (9.6 ± 1.2) mm and between two age groups [ young group, (9.6 ± 1.2) mm, elderly group, ( 9.9 ± 1.3 ) mm ]. Conclusions The lower margin of the basement of external anal sphincter was a useful anatomic lanmark for localizing the anal verge,and could be definitely identified on the middle sagittal pelvic CT image. The distance between the structure and anal verge is constant enough and can be used in measuring distance from low rectal lesion to the anal verge.

Metabolic disturbances such as hypertension and insulin resistence,as well as cardiovascular events are more frequent in primary aldosteronism patients than in essential hypertension patients.When the diagnosis of primary aldosteronism is made,more attention should be paid to the associated metabolic disturbances and cardiovascular events,which may benefit the prognosis of patients.

Serial sections of human embryos and the brain stem together with cerebellum offetuses, young and adults were studied by Cajal I and Nissl methods for demonstratingthe development and connections of mesencephalic nucleus of the trigeminal nerve. It was found that at C.R. 12.4 mm the mesencephalic root with some scattered cellgroups made its appearance along the sulcus limitus from the entrance of the trigeminalnerve up to the isthmus region. At C.R. 56mm it extended into the midbrain regionand the base of the cerebellum. Later on, the root cells differentiated in a caudo-rostraldirection. They were therefore somewhat larger in its caudal part than those in the ros-tral. With the increase of age the morphology of the mesencephalic root cells alsochanged from the fetal multipolar type to the adult unipolar. The present study confirm the previous observations that the mesencephalic root hadconnections with some cranial nerves and the cerebellum. And in addition, some scat-tered mesencephalic root cells were found in the posterior commissure, in its nucleus andin the interstitial nucleus. Discussion on their functional significance were made.

17 young healthy rabbits weighing from 520 to 720 gins,ageing 38～48 postnatal days,were used for this study.Seven to fourteen days following spinal lesions at diffe- rent levels the animals were killed and serial transverse sections of thc brain stem were stained with thionin,the retrograde cell degenerations within the red nucleus were studied. An analysis of the chromatolysis indicates that the rubrospinal fibers are largely crossed and a few fibers to the cervical cord are uncrossed.Furthermore,a somatotopical localization exists within the contralateral red nucleus with respect to the rubrospinal tract,i.e.the cervical projections of the fibers system take origin from the dorsal part of the red nucleus almost throughout its whole extent,the thoracic projections from the ventral part of the caudal five-sixths of the red nucleus,and the lumbar projections from the centro-ventral part of the caudal third of the nucleus. It also indicates that all types of cells in the red nucleus,not only the large ones, give rise to the rubrospinal tract.The spinal porjections of this fiber tract may descend as far as the lumbar cord.

Objective To explore the curative effect of dissection steel plate treatment in humerus near end bone fracture curative effect.Methods From June 2000 to March 2006,dissection steel plate treatment was used in 31 cases of humerus near end bone fracture and Constant-Murley scores was used to evaluate the curative effect.Results All patients were made a follow-up for 10 to 24 months,the average 16.5 months.31 examples surgeries patient only superior 16 examples,good 10 examples,may 2 examples,difficult 3 examples.Conclusion Center 3 and 4 humeruses near ends bone fracture uses the dissection steel plate treatment to Neer dividing will be possible to obtain the good clinical effect.