Objective To observe the clinical effect of umbilical cord blood stem cell transplantation in the treatment of decompensated hepatic cirrhosis .Methods The umbilical cord blood of healthy puerperal women was collected,and stem cells were isolated and injected into liver through hepatic artery to treat 20 patients withdecompensated cirrhosis.Blood,liver function,coagulation changes ,indicators of clinical symptoms and adverse events were observed after transplantation 1 week,2 weeks,4 weeks and 8 weeks.Results 1 week after transplantation ,the fatigue,loss of appetite situation were improved in more than 80% patients,but the changes were not significant ( t=0.88,0.80, 0.20,0.23,0.56,all P>0.05).2 weeks after transplantation,the bloating of 60% patients was improved,ALB in-creased significantly(t=2.03,P<0.05).After 4 weeks,the bloating of 70%patients relieved,50%of patients with ascites subsided.ALB,ALT,PT were significantly improved (t=3.84,P <0.01;t =1.75,3.02,all P<0.05);8 weeks later,75%of patients with ascites subsided .Except for AST was not obvious ,other indicators were improved significantly(t=2.20,2.22,5.93,all P<0.05).Except for one case had low fever ,there were no other adverse reac-tions.Conclusion Cord blood stem cell transplantation in the treatment of decompensated cirrhosis can achieve a certain short-term treatment effects , especially in increasing the level of ALB and reducing PT , could resume liver damage and has relatively high security at the same time .

Objective To investigate the skull base meningiomas communicate through the superior orbital fissure cranio-orbital approach of microsurgical Methods and the efficacy.Methods 80 cases with skull base meningiomas were randomly divided into the control group and observation group,40 cases in each group.The control group was given contact microsurgery,and the observation group received communication through the superior orbital fissure cranio-orbital approach of micro-surgery.The improvement of symptoms and postoperative complications were compared and analyzed.Results (1)The operative time,blood loss,blood transfusion,Simpson grade (Ⅰ,Ⅱ,Ⅲgrade),DKPS,postoperative hospital stay and mortality rate in the control group were (9.28 ± 0.97)h,(1 222.38 ± 89.07) mL,(1 099.35 ±56.72) mL,14/17/9,3.21 (0,6.44),(29.78 ±3.29)d and 7.50％ (3/40),which in the observation group were (7.02 ± 0.65) h,(877.34 ± 44.50) mL,(677.10 ± 32.28) mL,29/9/2,3.26 (-3.33,10),(20.00 ± 2.75) d and 5.00％ (2/40).The differences of operative time,blood loss,blood transfusion,Simpson level,postoperative hospital stay between the two groups were statistically significant(t =4.209,4.997,5.823,x2 =4.011,t =5.711,P =0.033,0.027,0.018,0.022,0.013),but the D KPS and mortality between the two groups had no significant differences (t =0.433,0.096,P =0.089,0.317).The monocular prominent,eye movement disorder and vision improvement rates in the control group were 66.67％,72.22％ and 75.68％,which were significantly lower than 92.31％,94.12％ and 97.14％ in the observation group (x2 =5.932,4.381,6.793,P =0.027,0.033,0.020).The postoperative eye movement disorder,on ptosis,eye abduction,subcutaneous fluid and intracranial infection rates in the control group were 10.00％,15.00％,30.00％,12.50％ and 7.50％,those in the observation group were 7.50％,5.00％,10.00％,10.00％ and 7.50％.The postoperative eye movement disorder,subcutaneous fluid and intracranial infection rates had no significant differences between the two groups(x2 =0.923,1.033,0.785,P =0.387,0.595,0.233).The incidence rates of postoperative ptosis,abduction eyeball had statistically significant differences between the two groups (x2 =6.299,7.889,P =0.018,0.009).Conclusion The skull base meningiomas communicate through the superior orbital fissure cranio-orbital approach of microsurgery has significant effect than the conventional contact microsurgery,which deserves to be promoted in clinical.

Objective To compare the effect of gatifloxacin and levofloxacin for treating acute bacterial infection.Methods According to the digital table,228 patients with respiratory or urinary tract infections were randomly divided into group A and group B,114 cases in each group.Group A was given gatifloxacin 200mg,adding 5％ glucose injection 100ml intravenous drip injection twice daily; Group B was treated with levofloxacin 200mg,by adding 5％ glucose injection 100ml intravenous infusion twice daily.The treatment course lasted 7-14 days.The clincal effect,bacterial clearance rate and adverse reactions of the two groups were observed.Results The cure rate and total effective rate of group A was 68.4％,93.0％,respectively,which of group B was 66.7％,90.3％,respectively,the differences were statistically significant (x2 =0.184,0.213,all P ＞0.05).The bacterial clearance rate and bacterial drug sensitivity test sensitivity was 89.4％,78.8％,respectively,which of group B was 77.2％,70.3 ％,respectively,the differences were all statistically significant (x2 =4.812,4.236,all P ＜ 0.05).The incidence rate of adverse reactions of group A was 7.0％,which of group B was 6.1％,there was no statistically significant difference (x2 =0.672,P ＞0.05).Conclusion Gatifloxacin has better effect and lower adverse reactions in the treatment of acute bacterial respiratory or urinary tract infections,and there is no significant difference compared with levofloxacin treatment,and it is worthy of clinical application.

Objective To systematically evaluate the application effect of clinical pathways in children pneumonia patients by u-sing the system analysis .Methods Published RCT in children pneumonia patients were searched and screened in CNKI ,VIP ,CBM-disc and Wanfang datebase under present standards .The quality of the included studies were evaluated and statistical analyzed by RevMan5 .0 software .Results Total 17 literatures including 2 717 cases were eligible to the criteria (1 359 in clinical pathways group and 1 358 in control group)altogether .The system analysis showed there were significant difference between the clinical path-way group and the traditional treatment group in grasp of health knowledge [RR=1 .30 ,95% CI(1 .17 -1 .44) ,P<0 .01] ,rate of patients ,satisfaction[RR=1 .17 ,95% CI(1 .13 -1 .21) ,P<0 .01] ,length of hospital stay [WMD= -2 .90 ,95% CI(-3 .93 - -1 .86) ,P<0 .01] ,hospitalization expenses[WMD= -620 .02 ,95% CI(-838 .99 - -401 .04) ,P<0 .01] ,the body temperature to restore normal time[WMD= -1 .67 ,95% CI(-2 .10- -1 .23) ,P<0 .01] ,lung sound disappear time[WMD= -1 .80 ,95% CI(-2 .15- -1 .45) ,P<0 .01] .Conclusion Clinical pathways is superior compared with the traditional treatment for children pneumo-nia patients ,be worthy of spread in clinical .

This paper analyzes deficiencies of our journal in contribution source, quality of articles, correlative policy, editing system, journal feature, distribution, etc. Starting from the present conditions, it offers special suggestions on thesis quality control, conversion of the journal to a bimonthly, establishment of scientific editing system and the ways to make the journal prominent with its own feature, and to improve its overall academic standard by a series of measures.

Objective To observe the effect of edaravone on haemorheology in the patients with cerebral infarction. Methods 96 patients with cerebral infarction were collected and randomly divided into observation group and control group. 48 patients were divided into each group. Conventional thrombolysis therapy was used in control group,and salvia miltiorrhiza intervenous drop infusion after thrombolysis. Edaravone intervenous drop infusion after thrombolysis was used in observation group. The curative effect,neurologic impairment score,and the haemorheology index(the whole reduced viscosity,hematocrit, ESR and fibrinogen) were detected in all patients. Results All the patients got a good curative effect, the improved neurologic impairment score and the haemorheology index after different treatment. The curative effect,the neurologic impairment score and the haemorheology index were better in observation group after treatment than that in control group (all P＜0. 05). Conclusion Edaravone could play'a better therapeutical effect in patients with cerebral infarction by cleaning the free radical and improving the state of haemorheology.

Objective: To explore the path selection of national obligations in realizing the social security rights. Methods:Exemplification is applied to explore the problems in the realization of social security rights through the analysis of the specific circumstances of the operation of the New Rural Cooperative Medical System(NRCM). Results: Through analyzing the problems in the realization of social security rights under NRCM in China, the realization progress of social security rights not only have imperfections in legal system, but also have problems in insufficient fund and incomplete system, which lead to the low social security level of residents. Conclusion: To improve the realization of residents’ social security rights, the specific pathway was analyzed according to the pathway selection of fulfilling the China National Obligations. Pathway 1: enhance the legislation, implement the legal system of social security; pathway 2: based on the function display of administrative organ, enhance the supervision of administrative management; pathway 3: based on judicial remedy, secure the realization of social security right.

Objective To evaluate the effect of LTA on lung function in stable chronic obstructive pulmonary disease. Methods A randomized and double blind placebo-controlled clinical trail was conducted in 84 patients with COPD. 42 patients were treated by LTA and 42 patients were treated by placebo for 12 weeks. Results LTA provided significant improvement in inspiratory capacity(IC) ,forced expiratory volume in one second(FEV) and forced vital capacity(FVC). Conclusion LTA is an effective bronchodilator on improving lung function and health status in patients with stable COPD.

Exercise Therapy ; trends ; Humans ; Motor Activity ; Societies, Medical ; Sports ; trends ; Sports Medicine ; trends