Abnormal auditory responses is one of the common features in autism. The characteristics and pathogenesis of the abnormality is not quite clear. The results of electrophysiological hearing evaluation ( i. e,brainstem auditory evoked potentials, otoacoustic emissions) in autistic children are inconsistent. The abnormal aduitory responses may contribute to the poor social interaction and communication in autism.

With rapid developmerit of technology of three dimensional conformal radiotherapy(3DCRT)and intensity-modulated radiotherapy(IMRT),the immobilization and repetition of patients'treatment position need is more accurate.The setup errors of thoracic cancer patients are great because of the breathing motion of lungs.The method of utilizing CBCT(cone beam computered tomography)to verify and correct setup errors is convenient and effective.CBCT,as one way of imaging guided radiation therapy(IGRT),is directly fixed on linear accelerator,has an important role and broad application prospects in reduction of setup error.

Objective To observe the effect of edaravone on haemorheology in the patients with cerebral infarction. Methods 96 patients with cerebral infarction were collected and randomly divided into observation group and control group. 48 patients were divided into each group. Conventional thrombolysis therapy was used in control group,and salvia miltiorrhiza intervenous drop infusion after thrombolysis. Edaravone intervenous drop infusion after thrombolysis was used in observation group. The curative effect,neurologic impairment score,and the haemorheology index(the whole reduced viscosity,hematocrit, ESR and fibrinogen) were detected in all patients. Results All the patients got a good curative effect, the improved neurologic impairment score and the haemorheology index after different treatment. The curative effect,the neurologic impairment score and the haemorheology index were better in observation group after treatment than that in control group (all P＜0. 05). Conclusion Edaravone could play'a better therapeutical effect in patients with cerebral infarction by cleaning the free radical and improving the state of haemorheology.

Objective:To observe the in fluence of atorvastatin on serumlevels of IL-1?,TNF-?,OX-LDLand serumlipid in cerebral spontaneous hemorrhage to study its protection mechanisms for cerebral spontaneous hemorrhage.Methods:Sixty patients with cerebral hemorrhage were divided into normal serum lipid level group with cerebral spontaneous hemorrhage(A),and higher serum lipid level group with cerebral spontaneous hemorrhage(AH),normal serum lipid level cerebral spontaneous hemorrhage group with atorvastatin treatment(AT),and higher serum lipid level cerebral spontaneous hemorrhage group with atorvastatin treatment(AHT).Neurological deficiency score was examined.IL-1?,TNF-?,and OX-LDL were measured by enzyme linked immunosorbent assay;and serum lipid level was measured by biochemistry.Results:The serum levels of IL-1?,TNF-?,and OX-LDL in AT group were significantly decreased compared with those of A group(P0.05);The serum levels of IL-1?,TNF-?,and OX-LDL in AHT group were significantlylower than those in AH group,and compared with those at 2w,all the levels at 4wand 6wwere significantly lowe(rP

Radioiodine 131 treatment for Graves' hyperthyroidism began nearly 70 years ago,and it has been recognized as the mainstream therapy for Graves' hyperthyroidism in western countries due to its simplicity and high cure rate.Indications of radioiodine 131 treatment have been changing during the past decades,now its main indication is Graves' hyperthyroidism of adult patients,especially when the patients were complicated with heart disease,leucocytopenia or hepatic damage.In Western countries,the cure rate of radioiodine 131 treatment is approximately 100%,yet the incidence of hypothyroidism is above 50%.Now hypothyroidism is accepted as an inevitable outcome for many patients after radioiodine 131 treatment.Evidence-based experiments during the past 70 years also showed that the therapy did not increase incidences of malignancies or leukemia,and had no influence on genetics or reproduction.

Objective To evaluate the clinical effect and safety of gemcitabine plus carboplatin regimen in the treatment of advanced non-small cell lung cancer(NSCLC) in aged patients. Methods 110 cases of aged patients with NSCLC , were divided into GEM group and NVB group according to the patients "options. GEM group received 1 000 mg/m2, GEM at day 1 and 8, and AUC 5 CBP at day 1. NVB group underwent the therapy of 2.5 mg/m2, NVB at day 1 and8,and 80 mg/m2 DDP at day 1 and 3. Both were treated with 21 days as a cycle. Results Overall re-sponse rate was 75.0% in GEM group and 72.0% in NVB group without significant difference( P>0.05). The medi-an survival time(MST) ,disease median response time(DPT) and one year survival rate were similar in two groups( P>0.05). The incidence of adverse reactions was significantly lower in GEM group than in NVB group ( P<0.05 ).Conclusion Gemcitabine plus carboplatin regimen is effective and safe in treatment of advanced non-small cell lung cancer in aged patients

This paper analyzes deficiencies of our journal in contribution source, quality of articles, correlative policy, editing system, journal feature, distribution, etc. Starting from the present conditions, it offers special suggestions on thesis quality control, conversion of the journal to a bimonthly, establishment of scientific editing system and the ways to make the journal prominent with its own feature, and to improve its overall academic standard by a series of measures.

Many voting activities such asThe Best Medical Workers put medical workers onto moral high ground,while medical dispute,medical anomie and other news pushed them to the abyss of criticism.These are all involved in the pan-moralization of medicine-related consensus of mass media.Taking specific opinion as example,this paper listed the pan-moralization characteristics including judging the complicated problems with ethical standard merely,evaluating behaviors of physicians and patients with idealistic principles,determining the whole moral outlook from the individuals,analyzed the reason of social emotional outbursts,traditional moral interference,media ethics anomie,and lack of public rationality,and finally proposes the strategies to avoid pan-moralization of medicine-related consensus from the micro and macro level.

Objective To summarize the progresses in psychological medicine made domestically and abroad,especially in PLA,during the period of "Eleventh Five-Year Plan" ,and propose a suggestion for the development of psychological medicine in the period of "Twelfth Five-Year Plan".Methods To retrospectively review and summarize the literature concerning psychological medicine and related subjects published domestically and abroad in past 5years retrieved from PubMed and CNKI.Results During the period of "Eleventh Five-Year Plan" ,researches on psychological medicine and related subjects had become one of the hot topics receiving agreat deal of attention by the governments and academic circles all over the world.New progresses had been achieved in the fields of psychological medicine services,epidemiological researches,networking psychiatry,etiology and pathological mechanism of mental illness,researches in treatment,stress disorder,and mental health in general hospitals,etc.In PLA,the incidence of schizophrenia and other serious mental illnesses declined significantly,but the prevalence rate of anxiety and depression showed a rising trendency among servicemen in peacetime. The development of military psychological medicine was affected in some extent by the organizational system and adjustment of organizational structure of the army.There still existed some problems to be improved such as the lack of high-tech personnel and staff training.Conclusions The great changes in socio-economics and culture produced a new demand on mental health services.The hot spots of researches of psychological medicine will still focus on biological psychiatry,the treatment of mental illness,social psychiatry and development of psychology,etc.

Vascular endothelial growth factor (VEGF) family consists of a group of secreted dimeric glycoprotein with a cysteine knot motif of regularly spaced eight cysteine residues,which plays a key role in vasculogenesis,angiogenesis and lymphangiogenesis via their special receptors.VEGF-A,one of VEGF families,is essential for vasculogenesis and angiogenesis.So inhibition of VEGF is available in the treatment of cancer and some diseases of pathological angiogenesis.Some studies imply that VEGF receptor-2 (VEGFR-2)is expressed in some nonvascular tissue and exerts an important role in the differentiation and survival of the cells.The expressions of VEGF and VEGFR-2 in lens epithelial cells(LECs) can be detected in the formation of lens vescle in embryo stage to adult.VEGF secreted by lens itself is concerned with the differentiation and development of lens via autocrine and paracrine.