Vascular endothelial growth factor (VEGF) family consists of a group of secreted dimeric glycoprotein with a cysteine knot motif of regularly spaced eight cysteine residues,which plays a key role in vasculogenesis,angiogenesis and lymphangiogenesis via their special receptors.VEGF-A,one of VEGF families,is essential for vasculogenesis and angiogenesis.So inhibition of VEGF is available in the treatment of cancer and some diseases of pathological angiogenesis.Some studies imply that VEGF receptor-2 (VEGFR-2)is expressed in some nonvascular tissue and exerts an important role in the differentiation and survival of the cells.The expressions of VEGF and VEGFR-2 in lens epithelial cells(LECs) can be detected in the formation of lens vescle in embryo stage to adult.VEGF secreted by lens itself is concerned with the differentiation and development of lens via autocrine and paracrine.

190 cases of rectal cancers were treated by operation from 1986-1993 at the Cho Ray Hospital. Analyzing some characteristics: pathology, classification of dukes, choosing the therapeutic method, evaluating, post-operative observation. The mortality rate, the operative accidents, the post-operative complications, the recurrence, the 5 years post -surgical prognosis: radical operations were still little. The choice of surgical procedure depended on location and the stage of carcinoma as the patients condition. Sphincter preservation will be performed more if the disease is diagnosed early
Rectal Neoplasms ; Methods

During 8 years from 1986-1993, 35 rectal cancer cases were treated by Hartmann procedure at Chî RÉy hospital' s General surgery Department. This procedure was performed for the middle-third of rectum (85.7%) and unmetastasis stage. Results: the operation related mortality rate was: 2.9%. Severe bleeding happened in 3 cases during operation: 8.5%. The most commonly occurred post-operative complication was infection and the most severity was pelvic abscess. The surgery of 24/34 patients, the prognosis was favorable: The 5 years survival rate was 83.3%, the recurrent rate was 11.7% and post-operative metastasis was 5.7%.
Rectal Neoplasms ; Therapeutics

During 8 years from 1986- 1993, we applied the Miles, operation to treat 44 patients who had got rectal cancer at Chî RÉy Hospital, General Surgery Department. This procedure was performed on the low rectal cancer: 1/3 low rectum (77,3%), 1/3 middle rectum (22,7%). Results: - The bleeding happened during operation: 6,8%. - The vaginal perforation:3,2%. - The most post- operative complication was: perineum infection(47,7%). - The mortality rate was: 4,6% and the recurrent rate was:13,6%. The 5 year survival according to Dukes’ classification was: A(100%), B (77,8%), C(25%).
Rectal Neoplasms ; Therapeutics

BACKGROUND:As a lubricant of artificial organs,lubricant capacity of blood is influenced by many factors,including hematocrit.OBJECTIVE: To explore the effect of hematocrit on blood lubricant capacity．METHODS: The lubricant capacities of four Kinds of hematocrit blood were studied by GB3142-82 lubricants-determination of bearing capacity testing.In addition,the differences of worn spots and the adsorption film formed on the steel ball under different hematocrit blood lubricating were observed by the Leica DMI 5000M material microscope．RESULTS AND CONCLUSION: ①The microshape of the adsorption films was depended on the hematocrit.②The greater hematocrit levels,the smaller worn spots formed on the steel ball,namely,increased hematocrit lead to stronger bearing capacity.

Objective To provide an optimal working process for crossmatching by full-automatic blood typing instrument.Methods Two workflows were applied to crossmatch test by full-automatic blood typing instrument.One was diluting red blood cells of donor samples to concentrate of 1%,the other was detecting directly the donor′s packed red blood cells.Compared consistency and processing time of the two different workflows.Results Cross match results of two workflows were consistent well(U=0,P>0.05).The average processing times before testing and undergoing testing were not significantly different(t=0.692,t=0.562,P>0.05),whereas the average processing times after testing and throughout testing were significantly different(t=146.485,t=67.053,P<0.05).Conclusion The workflow of diluting donor′s sample before testing saved processing time and better suits hospital having a large quantity of specimens.

Objective To explore the effects of different levels of selenium nutrition on thyroid function,liver deiodinase type Ⅰ(DⅠ) and brain deiodinase type Ⅱ(DⅡ) activities in experimental autoimmune thyroiditis (EAT) rats. Methods A total of 32 female Lewis rats were randomly divided into four groups that included control group,model group,EAT with selenium-supplementation group and EAT with selenium-deficiency group. After two weeks of the basal diet administration,the rats were fed on forage containing different levels of selenium for nine weeks and the total intake of selenium were 4,4,40 and 0.4 ?g/d,respectively. The rats of model group,EAT with selenium-supplementation group and EAT with selenium-deficiency group were induced to establish the model of experimental autoimmune thyroiditis from the third week to eighth week. The pathological change of thyroid was examined,and the levels of selenium in the blood,serum thyroid autoantibody and thyroid hormone,DⅠ and DⅡ activities were measured simultaneously. Results Compared with control group,thyroid autoantibody and thyroid hormone levels significantly increased in model group,EAT with selenium-supplementation group and EAT with selenium-deficiency group (P

Objective To discuss the clinical curative effects of Kaihoujian spray in the treatment of acute suppurative tonsillitis in children. Methods 120 cases of pediatric patients with acute suppurative tonsillitis were selected and randomly divided into the observation group and the control group (60 cases in each group); the control group were given conventional western medicine treatment, while the observation group received Kaihoujian spray on the basis of the control group treatment; clinical symptoms and curative effects of the two groups were evaluated and compared. Results In the observation group, sore throat and fever disappearance time, purulent secretion, tonsil swelling disappearance time and hemogram recovery time were all significantly shorter than those in the control group (P<0.05); after 3 courses of treatment, in the two groups, children temperature, sore throat, tonsil fester and tonsil swollen main symptom scores were all significantly decreased (P<0.05), but the observation group decreased more obviously (all P<0.05). After treatment, C-reactive protein, white blood cell count, neutrophils of the two groups all significantly reduced (P < 0.05), but the observation group decreased more obviously (all P<0.05). Conclusion Using Kaihoujian spray to treat acute suppurative tonsillitis could significantly improve the clinical symptoms and signs, whose clinical curative effect is good, and has no adverse reactions.

砄bjective: To evaluate the effect on a transpalatal arch on reinforcing anchorage. Methods: 12 cases with ClassⅡ Division 1 malocclusion were selected and treated with a transpalatal arch for reinforcing anchorage. Results: ①The forward displacement of the first maxillary molar (6 Ptmo, 6 So, 6CR So and 6AP So) , the backward displacement(1 Ptmo and 1 So ) and the reduction of the axial inclination (1 NA and 1 SN) of the upper incisors were increased( P 0.05);③The forward displacement of the first maxillary molar was less than one third of the extraction space ( P

Background The incidence of myopia is gradually increasing,and how to choose a better corrective method of myopia for the best visual demand is very important.Objective This study was to compare visual quality of implantable collamer lens (ICL) implantation with femtosecond laser in situ keratomileusis (FSLASIK) for moderate and high myopia using double-pass optical quality analysis system (OQAS).Methods A non-randomized controlled clinical trail was performed.Fifty-two eyes with-4.00 to-9.00 D of 26 consecutive patients were included in NO.1 Hospital of Xi'an from January 2015 to January 2016.Twenty-four eyes of 12 patients with the corneal thickness ＜500 μm received ICL implantation as ICL group and 28 eyes of 14 patients which corneal thickness was ≥500 μm underwent FS-LASIK surgery as FS-LASIK group.The demography was matched between the two groups (all at P＞0.05).All the patients were followed-up for 3 months after surgery.The preoperative best corrected distance visual acuity (BCDVA),spherical equivalent (SE),postoperative uncorrected distance visual acuity (UCDVA),BCDVA and SE were examined and compared between two groups.The parameters from OQAS were evaluated and intergrouply compared,including the objective scattering inders (OSI),modulation transfer function (MTF) cut off frequency,Strehl ratio and OQAS values under the contrast of 100％,20％ and 9％ (OV100,OV20,OV9).Results The postoperative BCDVA was not significantly different from preoperative UCDVA in both ICL group and FS-LASIK group (-0.04±t0.10 vs.0.05±0.12;-0.07±0.12 vs.0.00±0.12) (t=3.128,2.358,both at P＞0.05).No statistically significant differnces were found in SE,UCDVA and BCDVA after operation between ICL group and FS-LASIK group (t =1.292,0.900,-0.653,all at P＞0.05).OQAS examination showed that MTF cut off,OSI,Strehl ratio,OV100 were not significantly different after operation between ICL group and FS-LASIK group (t=-2.032,-1.440,-0.224,all at P＞0.05).The postoperative OV20 and OV9 were 0.82±0.14 and 0.80±0.21 in the ICL group,which were significantly higher than those in the FS-LASIK group(0.59±0.15 and 0.47±0.13) (t =4.105,4.702,both at P＜0.05).Conclusions Both ICL implantation and FS-LASIK provide good optical and visual quality for moderate to high myopic eyes,and ICL appears to have a better visual quality in comparison with FS-LASIK under the contrasts of 20％ and 9％.