1.Some remarks on lymph node dissection and recovering of gastrointestinal circulation after gastrectomy caused by cancer at B15 department of Military Central Hospital N.108
Duong Trieu Trieu ; Hai Tien Le ; Tam Thanh Nguyen ; The Ngoc Do ; Hoai To Nguyen
Journal of Surgery 2007;57(1):73-79
Background: Gastric cancer is a common disease in the world. For treatment, gastrectomy is still considered as the first choice. However, recovering of postoperative gastrointestinal circulation remains a controversial issue. Objectives: To assess the early results of 2 methods as gastroduodenostomy (Billroth I type) and gastrojejunostomy (Billroth type II) in recovering of gastrointestinal circulation. Subjects and method: A descriptive, retrospective study was conducted on 98 patients (61 males, 37 females, mean aged 48.1\xb112.7), were confirmed diagnosed with gastric cancer, treated in Military Central Hospital N.108 from May, 2001 to December, 2005. Results: Tumor positions were seen in 1/3 lower and 1/3 middle of gastric organ (59.2% and 40.8%, respective). There was no significant difference for invasive level of tumor between 2 groups (P>0.05). 62.2% patients with invasive level of tumor in stage of T4 in both 2 groups. Generally, the lesion between 2 forms of ulcer and rough differed significantly. The patients with and without metastatic lymph nodes were 57 and 41 patients, respective. All of patients were conducted with lymph node dissection at the stage of DIII-DIV. The difference between 2 groups for surgical time was no statistic significant. Conclusion: Billroth type I method combined with lymph nodes dissection was a safe and feasible technique in treatment of gastric cancer.
Stomach Neoplasms/ surgery
;
Gastrectomy
;
Lymph Node Excision
;
2.Study fluctuation and confirmation of Japanese encephalitis vector in Ha Nam province, 2006-2007 \r\n', u'\r\n', u'
Thoang Dinh Dang ; Tam Ngoc Nguyen ; Trang Minh Bui ; Yen Thi Nguyen ; Nga Thi Phan
Journal of Preventive Medicine 2008;0(3):45-53
Background: Japanese Encephalitis (JE) virus is a leading cause of encephalitis in children with high mortality and complication. JE is a dangerous infectious disease via Culex mosquitoes. Objective: To identify the density of some mosquitoes and vectors that transmit JE virus in Ha Nam province. Subject and Method:There were 30.333 mosquitoes including 05 genera and 15 species which were collected at night from April 2006 to March 2007 in the following communes: Tanson (midland area) Hungcong (plain area) and Liemchinh (suburban area). Results: A total of 06 Culex species, the highest rate is Culex tritaeniohychus (41.20%); Culex annulus (15.56%); other Culex species occupied around 0.15% -2.49%. In these communes, the density of Culex tritaeniohychus was higher than Culex annulus. They were found to be active all year round, but the highest density of Culex tritaeniohychus and Culex annulus is 5.86 and 2.15, respectively in April and fall to 4.35% and 1.71% in July. The collected mosquitoes during April, May, June and July includes 133 and 28 Culex tritaeniohychus and Culex annulus pools, respectively; all were to be processed for the isolation of Japanese Encephalitis (JE) virus. There were 12 Culex tritaeniohychus and 2 Culex annulus pools which were collected in Tanson commune yielding positive. Conclusion: The results were confirmed that Culex tritaenioohychus and Culex annulus are the major vectors that transmit JE virus in Ha Nam, 2006 - 2007. All 14 JE virus strains were isolated from collected mosquito pools during April, May and June; whereas JE virus strain was not yet isolated from collected mosquito pool in July. Thus, in order to control JE disease, it is necessary to control JE vectors in April, May and June.
Vector
;
Culex tritaenioohychus
;
Japanese encephalitis
;
Ha Nam
3.Does conventional freezing affect sperm DNA fragmentation?
Minh Tam LE ; Thai Thanh Thi NGUYEN ; Tung Thanh NGUYEN ; Trung Van NGUYEN ; Tam An Thi NGUYEN ; Quoc Huy Vu NGUYEN ; Thanh Ngoc CAO
Clinical and Experimental Reproductive Medicine 2019;46(2):67-75
OBJECTIVE: Sperm cryopreservation has been widely used in assisted reproductive technology, as it offers great potential for the treatment of some types of male infertility. However, cryopreservation may result in changes in membrane lipid composition and acrosome status, as well as reductions in sperm motility and viability. This study aimed to evaluate sperm DNA fragmentation damage caused by conventional freezing using the sperm chromatin dispersion test. METHODS: In total, 120 fresh human semen samples were frozen by conventional methods, using SpermFreeze Solution as a cryoprotectant. Routine semen analysis and a Halosperm test (using the Halosperm kit) were performed on each sample before freezing and after thawing. Semen parameters and sperm DNA fragmentation were compared between these groups. RESULTS: There was a significant decrease in sperm progressive motility, viability, and normal morphology after conventional freezing (32.78%, 79.58%, and 3.87% vs. 16%, 55.99%, and 2.55%, respectively). The sperm head, midpiece, and tail defect rate increased slightly after freezing. Furthermore, the DNA fragmentation index (DFI) was significantly higher after thawing than before freezing (19.21% prior to freezing vs. 22.23% after thawing). Significant increases in the DFI after cryopreservation were observed in samples with both normal and abnormal motility and morphology, as well as in those with normal viability. CONCLUSION: Conventional freezing seems to damage some sperm parameters, in particular causing a reduction in sperm DNA integrity.
Acrosome
;
Chromatin
;
Cryopreservation
;
DNA Fragmentation
;
DNA
;
Freezing
;
Humans
;
Infertility, Male
;
Male
;
Membranes
;
Reproductive Techniques, Assisted
;
Semen
;
Semen Analysis
;
Sperm Head
;
Sperm Motility
;
Spermatozoa
;
Tail
4.Thinning and drilling laser-assisted hatching in thawed embryo transfer: A randomized controlled trial.
Minh Tam LE ; Thi Tam An NGUYEN ; Thi Thai Thanh NGUYEN ; Van Trung NGUYEN ; Dinh Duong LE ; Vu Quoc Huy NGUYEN ; Ngoc Thanh CAO ; Alar AINTS ; Andres SALUMETS
Clinical and Experimental Reproductive Medicine 2018;45(3):129-134
OBJECTIVE: In frozen and thawed embryos, the zona pellucida (ZP) can be damaged due to hardening. Laser-assisted hatching (LAH) of embryos can increase the pregnancy rate. This study compared thinning and drilling of the ZP before frozen embryo transfer (FET). METHODS: Patients were randomly allocated into two groups for LAH using thinning or drilling on day 2 after thawing. Twenty-five percent of the ZP circumference and 50% of the ZP thickness was removed in the thinning group, and a hole 40 µm in diameter was made in the drilling group. RESULTS: A total of 171 in vitro fertilization/intracytoplasmic sperm injection FET cycles, including 85 cycles with drilling LAH and 86 cycles with thinning LAH, were carried out. The thinning group had a similar β-human chorionic gonadotropin-positive rate (38.4% vs. 29.4%), implantation rate (16.5% vs. 14.4%), clinical pregnancy rate (36.0% vs. 25.9%), miscarriage rate (5.8% vs. 2.4%), ongoing pregnancy rate (30.2% vs. 23.5%), and multiple pregnancy rate (7.0% vs. 10.6%) to the drilling LAH group. There were no significant differences in pregnancy outcomes between subgroups defined based on age (older or younger than 35 years) or ZP thickness (greater or less than 17 µm) according to the LAH method. CONCLUSION: The present study demonstrated that partial ZP thinning or drilling resulted in similar outcomes in implantation and pregnancy rates using thawed embryos, irrespective of women's age or ZP thickness.
Abortion, Spontaneous
;
Chorion
;
Embryo Transfer*
;
Embryonic Structures*
;
Female
;
Humans
;
In Vitro Techniques
;
Methods
;
Pregnancy
;
Pregnancy Outcome
;
Pregnancy Rate
;
Pregnancy, Multiple
;
Reproductive Techniques, Assisted
;
Spermatozoa
;
Zona Pellucida
5.Epidemiological characteristics of HIV/AIDS patients and community care in Thua Thien Hue
Ngoc Thi Tran ; Son Dinh Nguyen ; Minh Quang Duong ; Hoa Thai Nguyen ; Tam Le Nguyen ; Son Van Ly ; Son Huu Le ; Dung My Tran ; Hao Van Huynh
Journal of Preventive Medicine 2007;17(4):39-44
Background: HIV/AIDS pandemic really become danger to mankind on the earth. Objectives: Description epidemiological characteristics of HIV/AIDS patients. Studying clinical expression, learning aboutdemands of infected patients and community care for infected patients. Subjects and method: 71 HIV/AIDS people in Thua Thien Hue were studied in 2006. Using descriptive method to give epidemiological characteristics and behaviour of HIV/AIDS people. People were determined HIV/AIDS infection based on the criteria of Ministry of Health. The information were collected by target study. Results: HIV/AIDS people mainly from the age of 20 to 39 (83,10%), males were 52,10% and in various levels of education and all kinds of occupation. The rate of sexually transmitted infection was 84,5% and infection transmission was 15,5%. The rate of sexually transmitted infection within the last 12 months was 57,7%. 63,4% of infected people used condom while having sex with their spouses or partners. 1,4% of infected people using drug infection within the last month. 38% of the infected people had manifestations of AIDS, 77,8% of HIV/AIDS were treated with antiviral drugs. Families and communities had positive attitudes and behaviors to the HIV/AIDS people. Infected people being remoted from the society was 12,7%, 88,7% of them receiving supports from their communities such as disease treatment, spirit and material supports and job opportunities. Conclusion: Strengthen communication activities to change behavior of HIV/AIDS people and in communitiy to reduce alienation, discrimination for infected people. Execute socialization in care and support for HIV/AIDS people.
HIV/ immunology
;
isolation &
;
purification
;
pathogenicity
;
Community Health Services/ organization &
;
administration
;
Epidemiologic Methods
;
6.The situation of HIV/AIDS infection of prisoners at Binh Dien prison from 2005-2006
Tam Le Nguyen ; Minh Quang Duong ; Hue Thanh Dinh ; Son Dinh Nguyen ; Ngoc Thi Tran ; Hoa Thai Nguyen ; Son Van Ly ; Son Huu Le ; Dung Thi My Tran ; Hung Chi Nguyen
Journal of Preventive Medicine 2007;17(4):45-50
Background: With the development of HIV/AIDS pandemic in community, amount of HIV/AIDS people more and more increase in prison. Objectives: Determine the rate of HIV/AIDS infection of prisoners at Binh Dien prison. Learning about related elements to HIV/AIDS infection. Subjects and method: Prisoners at Binh Dien prison. Method: 492 prisoners were chosen, interviewed directly and taken blood samples to HIV test. Using cross-sectional study on accidental samples. Techniques were used in this study: SERODIA-HIV and ELISA technique. Results: The rate of current HIV/AIDS infections was 21,74%, some HIV/AIDS related factors in the prison included sex, religion, income source, marrital status, common knowledge of HIV/AIDS, drug addiction history, needle sharing, sexually transmitted disease history, body tatoos and forskin inserted with metal balls, alcohol and beer drinking history, some factors such as: age and educational level were not associated with HIV/AIDS infection in prison. Conclusion: Strengthen interventional activities in prison to prevent HIV/AIDS spread between prisoners. To prisoners who were not infected HIV/AIDS: strengthen educational communication to they may prevent themselves from HIV/AIDS infection behaviors. To HIV/AIDS prisoners: Need to educate and consult especially to they have right behaviors, prevent HIV/AIDS spread for the others while they were in prison as well as they return to society.
HIV Infections/ blood
;
complications
;
epidemiology
;
7.Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam.
Minh Tam LE ; Vu Quoc Huy NGUYEN ; Quang Vinh TRUONG ; Dinh Duong LE ; Viet Nguyen Sa LE ; Ngoc Thanh CAO
Endocrinology and Metabolism 2018;33(4):447-458
BACKGROUND: Polycystic ovarian syndrome (PCOS) is one of the most common endocrinopathies among reproductive-age women. Its metabolic features often overlap with those associated with metabolic syndrome (MS) and insulin resistance syndrome (IRS). The objective of this study was to determine the prevalence and predictors of MS and IRS in infertile Vietnamese women with PCOS. METHODS: A cross-sectional study was conducted at a tertiary fertility centre at Hue University Hospital from June 2016 to November 2017. A total of 441 infertile women diagnosed with PCOS based on the revised 2003 Rotterdam consensus criteria were enrolled. MS and IRS were defined based on the National Heart, Lung, and Blood Institute/American Heart Association Adult Treatment Panel III 2005 and American College of Endocrinology IRS 2003 criteria, respectively. Complete clinical and biochemical measurements of 318 women were available for analysis. Independent predictors of MS and IRS were identified using multivariate logistic regression. RESULTS: The overall prevalence of MS and IRS in women with PCOS was 10.4% and 27.0%, respectively. We identified older age (>30 years) and obesity as independent predictors of MS and IRS. Elevated anti-Müllerian hormone levels increased the risk of IRS, but not that of MS. CONCLUSION: MS and IRS are prevalent disorders among infertile Vietnamese women with PCOS. PCOS is not solely a reproductive problem. Screening and early intervention for MS and/or IRS based on anthropometric, metabolic, and reproductive hormone risk factors should be an integral part of fertility care.
Adult
;
Asian Continental Ancestry Group
;
Consensus
;
Cross-Sectional Studies*
;
Early Intervention (Education)
;
Endocrinology
;
Female
;
Fertility
;
Heart
;
Humans
;
Infertility
;
Insulin Resistance*
;
Insulin*
;
Logistic Models
;
Lung
;
Mass Screening
;
Obesity
;
Polycystic Ovary Syndrome*
;
Prevalence
;
Risk Factors
;
Vietnam*
8.The condition of cervical tooth wear and association with brushing habits among students of Hue University of Medicine and Pharmacy
Thi Quynh Thu LE ; Thi Hue Chi HUYNH ; Ngoc Tam Dan NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(6):58-
Background: Cervical tooth wear is a common oral health issue that often leads to the loss of tooth structure integrity, making the teeth sensitive, prone to plaque buildup, affecting the dental pulp, and causing aesthetic concerns. Assessing the extent of tooth erosion and its correlation with brushing habits is crucial for enhancing the effectiveness of necessary interventions and preventive measures. Objective: To determine the prevalence and severity of cervical tooth wear in young individuals aged 18-25 and examine the association between brushing habits and cervical tooth wear. Methods: A cross-sectional descriptive study was conducted on 60 undergraduate students from the Hue University of Medicine and Pharmacy, aged 18 - 25, who visited the Odonto-Stomatology Clinic, Family Medicine Center from November 2020 to April 2021. Study participants were interviewed and provided clinical examinations after obtaining their consent. Results: The study findings revealed a relatively high prevalence of cervical tooth wear (53.3%). Most cases exhibited a severity score 0 (no tooth wear), and no cases were classified as score 4. The highest prevalence of cervical tooth wear was observed in the left mandibular (65.6%). Regarding the association between cervical tooth wear and brushing habits, there was a significant correlation between horizontal brushing technique and brush hardness with cervical tooth wear (p < 0.05). However, there was no significant correlation between brushing frequency, toothbrush replacement time, brushing duration, and force applied during brushing with cervical tooth wear (p > 0.05). Conclusion: In general, the prevalence of cervical tooth wear is relatively high, and there exists a correlation between horizontal tooth brushing habits and brush hardness with the condition of cervical tooth wear. Therefore, implementing preventive measures against cervical tooth wear is crucial for enhancing oral health for everyone.
9.Prevalence and risk factors for human papillomavirus infection among female sex workers in Hanoi and Ho Chi Minh City, Viet Nam: a cross-sectional study
Quang Duy Pham ; Kiesha Prem ; Tuan Anh Le ; Nguyen Van Trang ; Mark Jit ; Tuan Anh Nguyen ; Van Cao ; Tam-Duong Le-Ha ; Mai Thi Ngoc Chu ; Ly Thi Khanh Le ; Zheng Quan Toh ; Marc Brisson ; Suzanne Garland ; Gerald Murray ; Kathryn Bright ; Duc Anh Dang ; Hau Phuc Trana ; Edward Kim Mulholland
Western Pacific Surveillance and Response 2022;13(4):1-11
Objective:
Female sex workers (FSWs) are at high risk of human papillomavirus (HPV) infections and cervical cancer due to their high number of sexual partners. The objectives of this study were to determine the prevalence of HPV and identify risk factors for high-risk HPV infection among FSWs in Hanoi and Ho Chi Minh City (HCMC), Viet Nam.
Methods:
A cross-sectional study was conducted in Hanoi and HCMC between December 2017 and May 2018. We surveyed and screened 699 FSWs aged ≥18 years for HPV infection and abnormal cytology. A multivariable modified Cox regression model was used to determine risk factors for high-risk HPV infection.
Results
The overall prevalence of any HPV, high-risk HPV and HPV-16/18 infection in the 699 FSWs was 26.3%, 17.6% and 4.0%, respectively, and were similar in both cities. Multiple infections were identified in 127 participants (69.0%).HPV-52 was the most prevalent (7%), followed by HPV-58 (6%). Abnormal cytology was detected in 91 participants (13.0%). FSWs who are divorced (adjusted prevalence ratio [aPR]: 1.96, 95% confidence interval [CI]: 1.01–3.81), widowed (aPR: 3.26, 95% CI: 1.49–7.12) or living alone (aPR: 1.85, 95% CI: 1.01–3.39) were associated with a higher prevalence of high-risk HPV infection.