In recent years, the unique nature of medical profession, overwork and increased medical lawsuits, have significantly complicated medical profession. In this stressful work environment, the shortage of nurses in most medical institutions has brought problems on staff turnover prevention to the forefront and increased the need for a variety of support measures to be taken to help counteract this high turnover. In order to create a better working environment in our hospital, we have begun grappling with the delivery of mental health care for our staff. In this report, we have checked new and inexperienced nurses in a questionnaire survey and recorded the findings over time. Immediately after their assignment, there was a very high incidence of physical and mental fatigue. It was revealed, however, that there were signs for improvements in fatigue as they had entered their second year of employment. That said, however, we found that there still remained a high degree of depression and a low degree of self-efficacy. Recognizing that being a nurse is a task with a high work load in a stressful work environment, we would like to reiterate the importance of creating a support system of ongoing education and stress management.