1.Clinical Studies of Physiological Effects of Natril Sulfas Siccatus Spring with Herbal Extract
Fujio ITO ; Kiyoko FURUYA ; Toshikazu TAKAGI ; Yoichi MOTOKI ; Takahiro KIYAMA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1982;46(2):84-92
The effect of the granules composed of Natril siccatus and herbal extracts in hydrotherapy was studied by recording skin surface temperature, deep body temperature from the intact skin, pletysmography, impedance pletysmography, blood pressure and subjective evaluation. These were measured before taking the testee into the Hubbart tank containing 0.0085% of herb granules at 40°C for 10 minutes, soon after taking a bath and at proper period until 2 hours.
The control study was done in simple water-bath in the same method. 30 testee were used for the test.
Results were as follows:
1. Skin surface temperature of H. G. group showed significant higher at the distal area of the extremities compaired with the control group.
2. Deep body temperature of H. G. group showed significant higher at right heel (10mm depth from the skin), palm (5mm) and calf (30mm) against the control.
3. The wave height of pletysmography of the index and the first toe of H. G. group was higher than the control at 100 minutes later.
4. IPG of H. G. group showed significant difference in upper and lower extremities against the control.
5. The change of the blood pressure showed no difference between two groups.
6. The subjective evaluation was scored and the t-test showed significant difference against the control, especially the difference was the most marked in utility feeling, and the effect of keeping warmth was in significant difference.
We may conclude that the H. G. in hydrotherapy has a sweet smell, make fell at home, keep warmth and play a role to promote blood circulation.
2.Development of a Novel Database That Rapidly Provides Valuable Information Efficiently Aimed at Improving the Safety of the Simple Suspension Method
Masahiro Watanabe ; Tatsuya Tai ; Shigeko Tsuji ; Hiroaki Tanaka ; Takahiro Motoki ; Kazunori Yamaguchi ; Kenta Sumiyoshi ; Takato Nozaki ; Masato Kaji ; Masato Asakura ; Shinji Kosaka ; Hitoshi Houchi
Japanese Journal of Drug Informatics 2015;17(2):69-76
Objective: Many patients in Kagawa University Hospital are administered medicines prepared by the simple suspension method. Pharmacists in charge of these patients receive inquiries from doctors and nurses regarding the suitability of medicines for the simple suspension method. Answering these inquiries is complicated and time-consuming as multiple data sources need to be searched. In order to simplify these complicated procedures, we herein attempted to develop a novel database to provide valuable information that could contribute to the safe performance of the simple suspension method, and evaluated its usefulness.
Method: The specifications of the database were determined by analyzing previously answered inquiries. To evaluate the usefulness of the database, we used test prescriptions and compared the amount of time required to gather information using the database and the conventional method, i.e., using books alone. We also analyzed previous prescriptions with the database in order to determine what kinds of problems could be detected.
Results: The investigation of previous prescriptions indicated that some medicines needed to be examined not only for their suitability for the simple suspension method, but also their incompatibility. Therefore, we added a feature regarding the incompatibility of medicines to the database. The time required to gather the information needed to answer the test prescription was shorter with our database than with the conventional method. Furthermore, the database improved the detection of medicines that require particular attention for their properties including incompatibility. An analysis of previous prescriptions using our database indicated the possibility of incompatibility in half of the previous prescriptions examined.
Conclusion: Our database could rapidly provide information related to the simple suspension method, including the incompatibility of medicines.