Objective To compare the prognosis and life quality of patients with early-stage breast cancer(stage I or II)undergoing breast-conserving surgery or modified radical mastectomy.Methods 180 cases with early-stage breast cancer were divided into 2 groups:breast-conserving surgery group(BCS)and modified radical mastcctomy group(MRM),with 90 cases in each group.The 2 groups were all given radiotherapy,chemotherapy and endocrine therapy according to indications.The prognosis and life quality in the 2 groups were compared.Results The 5-year-postoperative follow-up showed there was no significant difference in duration of disease-free survival(DFS)of the 2 groups.However,life quality of BCS patients was significantly better than that of MRM patients in terms of general health,physical function,pain,vitality,social functioning,emotion and mental health.Conclusion Breast-conserving surgery is highly recommended for patients with early-stage breast cancer.

The clinical data of 100 children or infants with penile hypospadias corrected with modified Snodgrass procedure during January 2013 to April 2016 from Yongchuan Hospital of Chongqing Medical University were retrospectively analyzed, including 50 cases aged <1 year (study group) and 50 cases aged >1 years (control group). The cure rates of study group and control group were 98% and 90%, and there was no significant difference between two groups (P>0.05). There were also no significant differences in intraoperative blood loss, postoperative ambulation time, length of hospital stay, pain scores and quality of life scores between two groups (P>0.05). However, the incidence of major complications, including urethral fistula, urethral opening stenosis, penis malunion, penile curvature in study group was lower than that in control group (P<0.05). This study indicates that hypospadias correction during infancy may achieve better outcomes.