1.HYPERBILIRUBINEMIA MIGHT BE A MARKER OF GANGRENOUS/PERFORATED APPENDICITIS: A RETROSPECTIVE STUDY
Buyantugs Ts ; Taivanbat J ; Nasanbat G ; Orgil N ; Erkegul B ; Odonchimeg B ; Bayarsaikhan B ; Davaadorj N ; Lkhagvabayar B
Journal of Surgery 2016;20(2):18-24
Introduction: Delayed or wrong diagnosis
in patients with appendicitis can result in
perforation and consequently increased
morbidity and mortality. Serum total bilirubin
may be a useful marker for appendiceal
perforation. The aim of this study was
to determine and compare pre-operative
total bilirubin level and other diagnostic
tools (patient age, duration of symptoms,
Alvarado score, white blood cell, C-reactive
protein, ultrasound and contrast enchanced
CT scan) in cases of acute appendicitis in
order to improve the clinical decision making.
Materialsand methods: We identified
102 patient with acute appendicitis after
excluding those with other causes of
hyperbilirubinemia among the 180 patients
that underwent a laparoscopic or an open
appendectomy from June, 2011 to March,
2015 in UB Songdo Private Hospital.
These cases were also subjected to
liver function tests and clinical diagnosis
was confirmed perioperatively and postoperatively
by histopathological examination.
According to histological results, these cases
were classified two groups: positive(acute
appendicitis with perforation and/or
gangrene) and negative(acute appendicitis
without perforation or gangrene). Their
clinical and investigative data were compiled
and analyzed. Statistical analysis was
performed using independent sample t test,
Chi square test, and direct logistic regression.
The level of significance was set at P< 0.05.
Results: Serum total bilirubin was found
to be significantly increased(1,5mg/dL) in
case of negative group and much higher
(3,6mg/dL) in cases of positive group (P
<0.001). The level of total bilirubin was
higher than 3 mg/dL in cases of gangrenous/
perforated appendicitis while in cases with
acute appendicitis it was lower than 3 mg/
dL. Also Alvarado score (P <0.01), C-reactive
protein (P <0.001) and contrast enchanced CT
scan (P <0.05) were statistically significant
diagnostic tools for acute appendicitis.
Conclusion: Assessment of preoperative
total bilirubin is useful for the differential
diagnosis of gangrenous/perforated
appendicitis.
2. HYPERBILIRUBINEMIA MIGHT BE A MARKER OF GANGRENOUS/PERFORATED APPENDICITIS: A RETROSPECTIVE STUDY
Buyantugs TS ; Taivanbat J ; Nasanbat G ; Orgil N ; Erkegul B ; Odonchimeg B ; Bayarsaikhan B ; Davaadorj N ; Lkhagvabayar B
Journal of Surgery 2016;20(2):18-24
Introduction: Delayed or wrong diagnosisin patients with appendicitis can result inperforation and consequently increasedmorbidity and mortality. Serum total bilirubinmay be a useful marker for appendicealperforation. The aim of this study wasto determine and compare pre-operativetotal bilirubin level and other diagnostictools (patient age, duration of symptoms,Alvarado score, white blood cell, C-reactiveprotein, ultrasound and contrast enchancedCT scan) in cases of acute appendicitis inorder to improve the clinical decision making.Materialsand methods: We identified102 patient with acute appendicitis afterexcluding those with other causes ofhyperbilirubinemia among the 180 patientsthat underwent a laparoscopic or an openappendectomy from June, 2011 to March,2015 in UB Songdo Private Hospital.These cases were also subjected toliver function tests and clinical diagnosiswas confirmed perioperatively and postoperativelyby histopathological examination.According to histological results, these caseswere classified two groups: positive(acuteappendicitis with perforation and/organgrene) and negative(acute appendicitiswithout perforation or gangrene). Theirclinical and investigative data were compiledand analyzed. Statistical analysis wasperformed using independent sample t test,Chi square test, and direct logistic regression.The level of significance was set at P< 0.05.Results: Serum total bilirubin was foundto be significantly increased(1,5mg/dL) incase of negative group and much higher(3,6mg/dL) in cases of positive group (P<0.001). The level of total bilirubin washigher than 3 mg/dL in cases of gangrenous/perforated appendicitis while in cases withacute appendicitis it was lower than 3 mg/dL. Also Alvarado score (P <0.01), C-reactiveprotein (P <0.001) and contrast enchanced CTscan (P <0.05) were statistically significantdiagnostic tools for acute appendicitis.Conclusion: Assessment of preoperativetotal bilirubin is useful for the differentialdiagnosis of gangrenous/perforatedappendicitis.
3.Study of pharmacopoeia of root of Caryopteris Mongolica Bge.
Namuunaa G ; Nomuundari M ; Tsetsegmaa N ; Taivanbat G ; Batkhuu J ; Davaapurev B
Mongolian Pharmacy and Pharmacology 2021;19(2):63-70
Introduction:
The main goal of the modern national drug manufacturer is to develop highly biological active, low-side effects and no toxicity pharmaceutical products that can replace synthetic drugs with natural animal, plant and mineral raw materials. We conducted this study in aim to develop the standard of pharmacopoeia of root of Caryopteris mongolica which an antibacterial activity plant that grows in Mongolia. The study included experiments to determine the appearance of the plant, to determine its anatomical structure, to determine the quantitative analysis of pharmacognosy and to determine the microbiological analysis.
Method:
We defined the appearance of plant by sensory method, anatomical structure of plant by light microscopy method. And we experimented the quantitative analysis of pharmacognosy and microbiological analysis of plant according to the methodology specified in the general requirements for medicinal plant raw material of the National Pharmacopoeia of Mongolia.
Conclusion
As a result of the study, the appearance of plant was brown, woody thick, has many branched roots, odorless and bitter. The quantitative analysis of pharmacognosy of plant met the general requirements for medicinal plant raw material. For microbiological analysis, plant met the all requirements.