1.Treatment of double loop double button plate fixation on patients with complete acromioclavicular joint dislocation
Clinical Medicine of China 2014;30(11):1202-1204
Objective To investigate the application of the double loop double button plate fixation on treatment of patients with complete acromioclavicular joint dislocation.Methods Twenty-six cases with Rockwood type Ⅲ complete acromioclavicular joint dislocation were selected as our subjects who hospitalized from Jan.2011 to Jul.2013 and underwent using dual loop button plate technology of double fixation and reconstruction of coracoclavicular ligament fixation.There were 19 males and 7 females.Their age ranged from 18 to 62 years old and average was 30.2 years old.Adopt Lazzcano standard score was used to evaluate the shoulder joint function.Results X-ray examination showed the acromioclavicular joint of all patients were fixed in right place.Shoulder function was back to normal after 1 to 2 months and no pain or mild pain were showed in some patients.Twenty-four cases were followed up for 6-24 months,and the average followed up periods was 18.2 months.According to Lazzcano standard score to assess the function of shoulder join.Twenty cases were excellent and 4 cases were in good.The excellent and good rate was 100%.Conclusion Dual loop button plate technique is proved to be a good approach in the treatment of complete acromioclavicular joint dislocation with small trauma,stable fixation.Meanwhile patients can perform early functional exercise and no recurrent dislocation without the need of internal re-fixation.
2.A New Homogenizing Technology to Obtain Rosmarinic Acid from Perilla Oil Meal
Weizhuo TANG ; Yanze LIU ; Yuqing ZHAO
Chinese Herbal Medicines 2012;04(1):70-73
ObjectiveTo optimize the extraction technology of the active component,rosmarinic acid,an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid,in perilla oil meal for the first time by a new homogenizing technology called smashing tissue extraction (STE).MethodsOrthogonal design was used to optimize the extraction condition.The content of rosmarinic acid was quantified from the methanol crude extract with the help of HPLC.ResultsThe optimization of STE process to get rosmarinic acid from the perilla oil meal was the ratio of liquid to solid material at 10∶1 and the power of extraction at 150 V,extracting twice (2 min for each time).ConclusionSTE could be applied to extracting the active ingredients from the oil meals due to its high extraction efficiency.This new homogenizing technology has advantages on saving extraction time,raising extraction efficiency,and maintaining the temperature sensitive constituents.
3.THE HIGH FREQUENCY ELECTROCARDIOGRAM OF 183 MIDDLE-AGED AND ELDERLY PEOPLE
Shuwang GAO ; Bingde LUO ; Yuqing LI ; Renyu CHEN ; Shengao TANG
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
The purpose of this study was to investigate and analyze the high frequency electrocardiogram (HFECG) for middle-aged and elderly people.138 subjects were chosen in our study.The mean age was 60.38 years.Among them,72.1 per cent were between 50 and 69 years.The results showed that (1) the differences were not significant between male and female groups in the mean number of high frequency notches (HFN).(2) For an increase in high frequency notches in the leads V1 and V2,we should consider the possibility of pathological changes of the anterior medial wall of heart,which was supplied by the dessending rami of the right anterior coronary artery,on the one hand,and it might remind us to pay great attention to posteromedian wall of heart,on the other hand.(3) Looking at all age groups in this study,we preliminarily found that the age peak of ischemic heart disease was between 50 and 70 years,according to the number of high frequency notches in the leads of HFECG.(4) The sensitivity of HFECG for diagnosing ischemic heart disease is 40 per cent higher than that of the conventional ECG.(5) In addition,nine leads were used in this examination,which not only preserved sensitivity of six leads but also could provide a localizing value for the diagnosis of heart disease.
4.Optimization of Smashing Tissue Extraction Technology of Schisandra chinensis Fruits by Orthogonal Test
Yun TANG ; Yanze LIU ; Ling HAN ; Yuqing ZHAO
Chinese Herbal Medicines 2012;04(3):259-262
Objective To optimize the extract technology of active lignins from the fruits of Schisandra chinensis.Methods The content of schizandrin,gomisin A,and deoxyschizandrin were selected as standards to evaluate the efficiency of smashing tissue extraction (STE).Solid-liquid ratio,extracting times,ethanol concentration,and extracting time were investigated through orthogonal test.Results The optimized conditions for STE were ten times amount of 80% EtOH,extracting for three times,and 2 min for each time.Conclusion STE could obtain relatively higher yield,simplicity of operation,and benefit for environment protection.It could be better choice for the extraction ofS.chinensis.
5.Genetic Supports of blaOXA-23 in Acinetobacter baumannii and Their Clinical Significance
Yong ZHANG ; Yuqing CHEN ; Zhengrong ZHONG ; Junfeng HU ; Kouxing ZHANG ; Yingchun TANG
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To study the genetic supports of OXA-23 in Acinetobacter baumannii isolates and investigate the relationship between imipenem resistance acquiring and use of antibiotics.METHODS Consecutive selection of the 24 highly susceptive A.baumannii clinical isolates by imipenem was carried out.Genes of carbapenemases were detected by PCR and the colonial relationship of these isolates was evaluated by ERIC-PCR.Plasmids conjugation experiments and blaOXA-23 hybridization were performed to explore the gene location of blaOXA-23.RESULTS From all 24 susceptible A.baumannii isolates 10 were selected,including 6 multi-colonial blaOXA23 harboring strains.Plasmid conjugation experiments and Southern blotting experiments demonstrated that blaOXA-23 was not associated with integrons.CONCLUSIONS BlaOXA-23 may exist in a certain subset of apparently carbapenem sensitive Acinetobacter strains.When under consecutive selective pressure,bacteria harboring blaOXA-23 become the predominant group and subsequently the antibiotics resistance properties appear.It highlights the reasonable use of this category of antibiotics.
6.Down-regulation effect of glucosides of cheanomeles speciosa on the levels of serum antibodies in rats with adjuvant arthritis
Yin CHEN ; Wei WEI ; Hong WU ; Liqin TANG ; Xiaoyu WANG ; Yuqing YANG
Chinese Pharmacological Bulletin 2003;0(07):-
Aim To study the effects of glucosides of cheanomeles speciosa(GCS)on the levels of serum antibodies in rats with adjuvant arthritis.Methods SD rats were divided randomly into six groups, including normal, model, GCS(30,60,120 mg?kg-1)and glucosides of tripterygium wifordii(GTW) groups. Complete Freund′s adjuvant was used to induce AA in rats. The level of circulating immune complexes in serum was determined by PEG 6 000 assay, while the levels of anti-CⅡ antibody, and anti-TB antibody in serum were measured by enzyme-linked immunosorbent assay(ELISA).Results GCS(30,60,120 mg?kg-1)and GTW(40 mg?kg-1)were given by intragastric administration for 8 days from the 17 th day after immunization. GCS(60,120 mg?kg-1)reduced the levels of circulating immune complexes, anti-CⅡantibody, and anti-TB antibody in serum in rats with adjuvant arthritis.Conclusions GCS down regulates the levels of serum antibodies in rats with adjuvant arthritis, which may be related to its efficacy in the treatment of rats with AA.
7.Effects of curcumin on proliferation and COL I expression of human circulating fibrocytes
Xuyan FU ; Piwen ZHAO ; Yadong LI ; Yuqing TANG ; Jianzhao NIU ; Hongjie WANG ; Yu LI
Chinese Pharmacological Bulletin 2014;(7):942-946,947
Aim To isolate and characterize the human circulating fibrocytes from human peripheral blood and explore the effects of curcumin on human circulating fi-brocytes.Methods The cells were isolated and puri-fied by density gradient centrifugation,and identified by flow cytometry and immunocytochemistry .Then , CCK-8 and flow cytometry were used to study the effect of curcumin on the proliferation as well as COL I ex-pression of human circulating fibrocytes,respectively. Results After being isolated the cells expressed CD34,CD45 and COLⅠ,among which 79.7% were both CD45 and collagen I positive,typical of human circulating fibrocytes.Curcumin could exert regulatory effects on proliferation of human circulating fibrocytes. Exposure of the cells to curcumin for as short as 24 hours promoted their growth,while prolonged treatment (72 h ) significantly inhibited cell propagation and downregulated the COLⅠ levels,best manifested at a concentration as high as 20 μmol · L-1 .Conclusion The proliferation of cells and COLⅠexpressions can be effectively inhibited by curcumin with the prolonged action period and high concentrations.
8.Effects of low dose simvastatin on the levels of plasma lipids,C-reactive protein and fibrinogen in patients with acute coronary syndrome
Dongxin JIANG ; Binjun QING ; Haifeng MIAO ; Yuqing YANG ; Wenjing TANG ; Shaoyu FU
Journal of Chinese Physician 2001;0(02):-
Objective To observe the changes of plasma lipid,C-reactive protein(CRP) and fibrinogen(FIB) in patients with acute coronary syndrome(ACS)treated with low dose simvastatin.Methods One hundred and twenty patients with ACS were randomly divided into treatment group and control group with 60 cases in each.The patients in the control group were treated with conventional therapy,and those in the treatment group were treated with 20 mg simvastatin per day at the base of control group.The course of treatment was 2 months.Results In the treatment group,the levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),CRP and FIB were decreased significantly and the level of high-density lipoprotein cholesterol(HDL-C) was increased after the treatment(all P0.05).Conclusion The levels of plasma lipid,CRP and FIB can be effectively regulated with the treatment of low dose simvastatin in patients with ACS.
9.Clinical efficacy of Viagra with behavior therapy against premature ejaculation.
Wenhao TANG ; Lulin MA ; Lianming ZHAO ; Yuqing LIU ; Zhenwen CHEN
National Journal of Andrology 2004;10(5):366-370
OBJECTIVETo study the efficacy of Viagra combined with behavior therapy against premature ejaculation (PE).
METHODSSixty PE patients were divided into two groups randomly: control group (behavior therapy alone) and the group of Viagra combined with behavior therapy. Intra-vaginal ejaculation latency time (IELT) and the coitus satisfaction of the patient and the partner were recorded before and after treatment.
RESULTSThe IELTs of the two groups were 0.80 +/- 0.20 and 0.73 +/- 0.24 minutes respectively before treatment, and 1.82 +/- 0.54 and 3.63 +/- 0.55 minutes respectively after treatment. As for IELT and satisfaction degree, Viagra produced better result than behavior therapy.
CONCLUSIONDuring this clinical trial, Viagra combined with behavior therapy prolonged IELT, which suggests that Viagra may be helpful for the treatment of premature ejaculation.
Adult ; Behavior Therapy ; Ejaculation ; drug effects ; Humans ; Male ; Middle Aged ; Piperazines ; therapeutic use ; Purines ; Sexual Dysfunctions, Psychological ; therapy ; Sildenafil Citrate ; Sulfones
10.Diagnosis and treatment of porcupine-like ichthyosis: a case report
Xibao ZHANG ; Xuemei LI ; Jianfang SUN ; Yuqing HE ; Xin TIAN ; Quan LUO ; Xiao XU ; Changxing LI ; Xin ZHOU ; Wei LI ; Li CUI ; Gengyun TANG ; Xinjing GAO
Chinese Journal of Dermatology 2010;43(11):801-804
A 10-year-old boy presented with a 3-year history of erythematous flat keratotic papules and brown-yellow, nail-like prominent keratotic plaques all over the body surface. Dermatological examination showed verrucous or nail-like prominence over multiple erythematous keratotic plaques on the head, face,trunk and limbs. The lesions, most of which confluenced, were covered with brown-yellow and greasy crusts,and gave a porcupine-like appearance. Skin biopsy of lesions from the back revealed epidermal hyperkeratosis,focal columnar parakeratosis, acanthosis, few acantholytic and dyskeratotic cells in stratum corneum, irregular upward proliferation of dermal papilla cells, and a superficial perivascular lymphocytic infiltration. A diagnosis of ichthyosis hystrix was established based on the histopathological findings. The boy was treated with oral acitretin and topical 0.1% acitretin cream for 8 years. The initial and maximum dose of oral acitretin was 0.5 mg·kg-1·d-1 and 1 mg·kg-1·d-1, respectively. Liver and kidney function, body height and weight were examined during the treatment, and no side effect was observed except for skin xerosis.