No abstract available.
Syphilis, Cutaneous*

No abstract available.
Syphilis, Cutaneous

No abstract available.
Syphilis ; Syphilis, Cutaneous

No abstract available.
Granuloma* ; Syphilis, Cutaneous*

A 32-year-old man is being presented with a 1-week history of erythematous annular flat plaque with scales on his scalp. He displays only a solitary skin lesion on his scalp without any presence or other histories for other skin lesions or constitutional symptoms. It is difficult to consider the possibilities of syphilis based on such clinical findings. A diagnosis of syphilid is being made on the basis of clinical, serological and histological findings. Herein, we report an interesting case of secondary syphilis which is presented as a solitary annular plaque on the scalp.
Adult ; Diagnosis ; Humans ; Scalp* ; Skin ; Syphilis* ; Syphilis, Cutaneous ; Weights and Measures

Rupioid syphilid is a type of pustular syphilis which accounts for <2% of cases of secondary syphilis. In pustular syphilis, pustules undergo central necrosis giving rise to "limpet-like" crusts resembling an "oyster shell." When the clinical findings are atypical, a diagnosis is made based on serologic testing. The prozone phenomenon occurs in <1% of patients with primary or secondary syphilis. This is a false negative reaction that occurs when very high antibodies in the serum prevent the formation of the antibody-antigen lattice needed to visualize a flocculation reaction. We report a case of rupioid syphilid in a pregnant woman accompanied by the prozone phenomenon. An accurate diagnosis was delayed because of atypical clinical findings and false-negative serologic results.
Antibodies ; False Negative Reactions ; Female ; Flocculation ; Humans ; Necrosis ; Pregnant Women ; Serologic Tests ; Syphilis ; Syphilis, Cutaneous

BACKGROUND: The differentiation of syphilids from other skin decreases is frequently difficult due to considerable variations of clinical and histologic pattern. The most common histologic changes in secondary syphilis are swelling & proliferation of endothelial cells and the presence of a perivascular infiltrate containing plasmia cells. But often, these findings are absert or inconspicuous. OBJECTIVE: We examined the histopathologic findings of secondary syphilis in relation to the clinical types of the skin lesion. MEHTODS: 36 biopsy specimens from twenty-nine serologically and clinically confirmed cases of secondary syphilis (15 macules, 8 papules, 2 condylomata latas and 11 papulosquamous lesions) were examined. RESULTS: The histopath,ologic findings of secondary syphilis showed comparative differences according to the clinical types of the skin lesion. The plasms cell infltrates were absent or sparse in 14 csses(39%) and the plasma cell infiltration was significantly correhted with the age of skin lesions(p=0.02197). Vascular changes were seen in 32 cases (89%), but the incidence of endothelial proliferation was less(25%). CONCLUSION: This study demonstrates the histopathologic findirigs of secondary syphilis in accordance to the clinical morphology of the eruption and thus, help to differentiate syphilids from other skin diseases.
Biopsy ; Endothelial Cells ; Incidence ; Plasma Cells ; Skin ; Skin Diseases ; Syphilis ; Syphilis, Cutaneous*

Psoriasiform lesion is a rare manifestation in secondary syphilis. A 34-year-old woman patient presented with a month history of condylomata lata on the perineum and erythematous scaling psoriasiform plaque on the back. The preliminary differential diagnosis included psoriasis and lichen simplex chronicus but a psoriasiform syphilid was confirmed through skin biopsies and serologic tests. We report a case of psoriasiform syphilid.
Adult ; Biopsy ; Diagnosis, Differential ; Female ; Humans ; Neurodermatitis ; Perineum ; Psoriasis ; Serologic Tests ; Skin ; Syphilis ; Syphilis, Cutaneous*

Nodular syphilis is an uncommon manifestation of secondary syphilis and may appear on any area of the body, with the head and neck often affected. The lesions are generally red-brown or violaceous. Although the nodular lesions are said to be more common in tertiary syphilis, most recent reports have diagnosed them as a manifestation of secondary syphilis in patients who may also exhibit mild lymphadenopathy without associated constitutional symptoms. We report a case of nodular syphilid in a 43-year-old man who presented with numerous papular, nodular and plaque skin lesions, without involvement of the mucous membranes.
Adult ; Head ; Humans ; Lymphatic Diseases ; Mucous Membrane ; Neck ; Skin ; Syphilis ; Syphilis, Cutaneous*

Nodular syphilis is an uncommon manifestation of secondary syphilis and may appear on any area of the body, with the head and neck often affected. The lesions are generally red-brown or violaceous. Although the nodular lesions are said to be more common in tertiary syphilis, most recent reports have diagnosed them as a manifestation of secondary syphilis in patients who may also exhibit mild lymphadenopathy without associated constitutional symptoms. We report a case of nodular syphilid in a 43-year-old man who presented with numerous papular, nodular and plaque skin lesions, without involvement of the mucous membranes.
Adult ; Head ; Humans ; Lymphatic Diseases ; Mucous Membrane ; Neck ; Skin ; Syphilis ; Syphilis, Cutaneous*