4-chloroanilline, 5-chlorosalicylanilid and 3,5-dichlorosalicylic acid are obtained by chlorination aniline and salicylic acid in difference conditions. Condensation of the above compounds with aniline, salicylic acid and each other to get chlorosalicylanilid derivatives. Chlorosalicylanilid derivatives have high antibiotic and antifungal activity. All most of chlorosalicylanilid derivatives has low toxicity.
Drug Compounding ; chemical synthesis

Study on some heterocyclic compounds used as drug for synthesis of sulphamethazine
Heterocyclic Compounds ; chemical synthesis

Methionyl - glycyl - funtumin was synthesized using mixed anhydride method with the hope of attaining a more active immunostimulant. The structure of the product was determined by IR, 1HNMR, 13CNMR spectroscopies.
Chemical synthesis ; Anhydrides

From essential oil of turpentine, the author have been separated a-pinen. Some derivatives e.g pinonic acid, oxypinocamphon and benzyl pinonat have been syntherized. 7 derivatives such as oxime, hydrazone, semicarbazone, thiosemicarbazone, 2,4-dinitrophenyl hydrazone and isonicotinoyl hydrazone have been prepared
Chemical synthesis ; Analogs & derivatives

From the essential oil of turpentive, the author have separated pinene. Some derivatives e.g. pinonic acid, oxypinocamphon and n-propyl pinonat were synthesized. 7 derivatives such as hydrazone, semicarbazone, thiosemicarbazone, 2,4 dinitrophenyl hydrazone and isonicotionyl hydrazone were prepared. The structures of the obtained products were characterized by elemental analyses and spectral methods (IR, UV). The biological activities of the products such as antibacterial and antifungal were tested. The results indicated that these compounds possessed biological activities, especially antibacterial activity.
Chemical synthesis ; Analogs & derivatives

The authors have performed the condensation of Vanillin with following compounds: Hydrazone, semicarbazid, thiosemicarbazid, phenylhydrazine, 2.4 -dinitronphenyhydrazine and iso- nicotinoyl hydrazine. 6 compounds derivatives have been synthesized. The structures of the obtained products were characterized by spectral methods(IR,UV). The biological activities of the resulting products as antibacterial and antifungal have been tested. The results indicated these compounds possessed high biological activities, especially antibacterial activity.
Chemical synthesis ; Analogs & derivatives

3-thioxo-3-arylamido-4-oxo-1,3thiazan derivatives were obtained by method dithiocarbamat. Condensation of 2-thioxo-3-arylamido-4-oxo-1,3-thiazan derivatives with phenylhydrazin to get 2-thioxo-3-arylamido-4-phenylhydranzon-1,3-thiazan derivatives. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had low antibacterial and antifungal activities.
Chemical synthesis ; Analogs & derivatives

By condensation of phenylisothiocyanate with amine compounds, thioure derivatives were obtained. The structures of the obtained products were determined by elemental analysis and IR spectroscopy. The study indicated that most of them had antibacterial and anti-fungal activities. Two compounds have good effect on Candida albicans
Chemical synthesis ; Antifungal Agents

Mequinol is a depigmenting (or demelanizer). It was syntheized from hydroquinol and methyliodid or dimethylsulfate, that are available materials. Method is simple and suistable to condition in Vietnam. The structure of the obtained product was characteritsed by chromatography, UV, IR and elemental analysis.
Chemical synthesis ; 4-hydroxyanisole

In order to explore the method to prepare hypoxia UW solution and the stability and preservation of hypoxia UW solution, UW solution was purged by argon or air for 15 min or 60 at a flow rate of 0.8 or 2 L/min, and the oxygen partial pressure of UW solution was detected. The hypoxia UW solution was exposed to the air or sealed up to preserve by using different methods, and the changes of oxygen partial pressure was tested. The results showed that oxygen partial presure of 50 mL UW solution, purged by argon for 15 min at a flow rate of 2 L/min, was declined from 242+/-6 mmHg to 83+/-10 mmHg. After exposure to the air, oxygen partial pressure of hypoxia UW solution was gradually increased to 160+/-7 mmHg at 48 h. After sealed up by the centrifuge tube and plastic bad filled with argon, oxygen partial pressure of hypoxia UW solution was stable, about 88+/-13 mmHg at 72 h. It was concluded that oxygen of UW solution could be purged by argon efficiently. Sealed up by the centrifuge tube and plastic bag filled with argon, oxygen partial pressure of UW solution could be stabilized.
Adenosine/chemical synthesis ; Allopurinol/chemical synthesis ; Anoxia ; Glutathione/chemical synthesis ; Insulin/chemical synthesis ; Organ Preservation/*methods ; Organ Preservation Solutions/*chemical synthesis ; Oxygen/*analysis ; Partial Pressure ; Raffinose/chemical synthesis