Objective To investigate the effects of peer education on treatment among patients using 131I with thyroid cancer after surgery.Methods A total of 80 patients using 131I therapy after surgery of thyroid can cerhospitalized from June 2014 to May 2016 were enrolled and randomly divided into two groups.The control group were given routine health care including hospitalized treatment,education,and follow-up examination after discharge from hospital,while the experimental group were given peer education,and the intervention was provided from admission to one month after discharge.Distress level,complication rates and knowledge mastering were compared between two groups.Results The differences of distress level,complication rates and knowledge mastering between two groups were statistically significant(P＜0.05).Conclusion Patients using 131I with thyroid cancer after surgery suffer from significant distress.Peer education can greatly reduce patients' distress,complications after 131I treatment,and improve mastering knowledge.

Objective To understand the status of Clonorchis sinensis infection and its risk factors in Futian District Shen?zhen City so as to provide the evidence for formulating the strategy of prevention and control. Methods Two monitoring points were randomly selected and the permanent population aged≥3 years were investigated and their stool samples were detected for the eggs of C. sinensis by using Kato?Katz technique. Meanwhile the risk factors of infection were also investigated. Results A total of 743 subjects were examined and 7 persons were infected with C. sinensis and the infection rate was 0.94%. Most of the infected cases were focused on 20?40 and 40?60 age groups. The risk factors were eating raw or semi?cooked fish and the protec?tive factor was the use of separated cutting board for cooked or uncooked food. Conclusion The infection rate of C. sinensis is low in the population of Futian District. However the health education especially for diet health education still should be strengthened.

AIM: To investigate the effects of ?-elemene,extracted from curcuma wenyujin,on proliferation, cell cycle and apoptosis of human multiple myeloma RPMI-8226 cells. METHODS: The effect of ?-elemene on the growth of human multiple myeloma RPMI-8226 cells was studied through MTT assay,cell cycle and apoptosis was studied by combined Annexin-V protein iodide staining,The morphological changes was studied by combining Hoechst33342-PI staining. RESULTS: ?-elemene inhibited the proliferation of RPMI-8226 cells in a time-and dose- dependent manner. Compared with the control cells,the proportions of the RPMI-8226 cells in the G0 /G1 phase rose,and the proportions of the RPMI-8226 cells in the S and G2 /M phases fell decreased. RPMI-8226 cells treated with ?-elemene for 48 h induced apoptosis in a dose-dependent manner. CONCLUSION: ?-elemene is able to inhibit the proliferation of RPMI-8226 cells by arresting the cell cycle and inducing the cell apoptosis.

OBJECTIVE: To establish an HPLC method for the determination of fumaric acid in Pleurotm citrinopileatus. METHODS: HPLC was performed on Yilite C18 column(250 mm?4.6 mm,5 ?m) with methanol-0.01 mol?L-1 potassium dihydrogen phosphate solution(5 ∶ 95,pH adjusted to 2.5 using phosphoric acid) as mobile phase and detection wavelength of 216 nm. RESULTS: The linear range of fumaric acid was 0.16～1.6 ?g (r=0.999 9). The average recovery was 101.59% (RSD=1.28%,n=6). CONCLUSION: This method is accurate, simple and reproducible for the content determination of fumaric acid in P. citrinopileatus.

Objective:To establish a risk prediction model for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) using regression analysis and verify the model.Methods:The risk factors and acute exacerbation of 1 326 patients with chronic obstructive pulmonary disease (COPD) who entered the stable phase and followed up for 6 months in the four completed multi-center large-sample randomized controlled trials were retrospectively analyzed. Using the conversion-random number generator, about 80% of the 1 326 cases were randomly selected as the model group ( n = 1 074), and about 20% were the verification group ( n = 252). The data from the model group were selected, and Logistic regression analysis was used to screen independent risk factors for AECOPD, and an AECOPD risk prediction model was established; the model group and validation group data were substituted into the model, respectively, and the receiver operating characteristic (ROC) curve was drawn to verify the effectiveness of the risk prediction model in predicting AECOPD. Results:There were no statistically significant differences in general information (gender, smoking status, comorbidities, education level, etc.), body mass index (BMI) classification, lung function [forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), etc.], disease status (the number and duration of acute exacerbation in the past year, duration of disease, etc.), quality of life scale [COPD assessment test (CAT), etc.] and clinical symptoms (cough, chest tightness, etc.) between the model group and the validation group. It showed that the two sets of data had good homogeneity, and the cases in the validation group could be used to verify the effectiveness of the risk prediction model established through the model group data to predict AECOPD. Logistic regression analysis showed that gender [odds ratio ( OR) = 1.679, 95% confidence interval (95% CI) was 1.221-2.308, P = 0.001], BMI classification ( OR = 0.576, 95% CI was 0.331-1.000, P = 0.050), FEV1 ( OR = 0.551, 95% CI was 0.352-0.863, P = 0.009), number of acute exacerbation ( OR = 1.344, 95% CI was 1.245-1.451, P = 0.000) and duration of acute exacerbation ( OR = 1.018, 95% CI was 1.002-1.034, P = 0.024) were independent risk factors for AECOPD. A risk prediction model for AECOPD was constructed based on the results of regression analysis: probability of acute exacerbation ( P) = 1/(1+ e- x), x = -3.274 + 0.518×gender-0.552×BMI classification + 0.296×number of acute exacerbation + 0.018×duration of acute exacerbation-0.596×FEV1. The ROC curve analysis verified that the area under ROC curve (AUC) of the model group was 0.740, the AUC of the verification group was 0.688; the maximum Youden index of the model was 0.371, the corresponding best cut-off value of prediction probability was 0.197, the sensitivity was 80.1%, and the specificity was 57.0%. Conclusion:The AECOPD risk prediction model based on the regression analysis method had a moderate predictive power for the acute exacerbation risk of COPD patients, and could assist clinical diagnosis and treatment decision in a certain degree.

Radioactive iodine therapy is a safe and effective postoperative treatment for patients with differentiated thyroid cancer. Since 131I is a radionuclide, the patient becomes a living radioactive source after receiving 131I treatment, causing radioactive damage to the surrounding population and the environment. This article reviews the necessity of radiation safety guidance for differentiated thyroid cancer patients undergoing 131I treatment and the content of radiation safety guidance during hospitalization and after discharge, aiming to provide reasonable guidance on radiation safety for these patients. It provides a reference for the formulation of radiation safety management plans in line with national conditions in the future.

Health science popularization is one of the key factors for patients with differentiated thyroid carcinoma treated with 131I to achieve positive survival outcomes. This paper reviews the general situation of health science popularization, the necessity of health science popularization for differentiated thyroid carcinoma treated with 131I and the current implementation situation at home and abroad, in order to provide reference for comprehensive health science popularization for differentiated thyroid carcinoma treated with 131I in clinical practice.

Objective To construct the evaluation index system of the core competence of the nurses in the nuclear medicine department and provide a scientific assessment tool for the core competence evaluation of nurses in the nuclear medicine discipline. Methods Based on the theory of core competence, we selected indexes and determined the weight of them by using literature retrieval, experts interview, Delphi expert consultation and the analytic hierarchy process(AHP) in order to analyze the concentration degree of expert opinion. The coordination degree of expert opinion was analyzed with the coefficient of variation (CV) and coordination coefficient. Finally, the weight of each index was calculated by the AHP. Results Expert enthusiasm: the effective recovery rate of the two rounds of expert consultation was 100%, and a total of 12 experts made personal suggestions. Expert authority analysis: judge coefficient (Ca=0.932) and familiarity degree coefficient (Cs=0.865), the expert's authorities (Cr=0.879). Expert opinion coordination degree: two rounds of expert consultation was CV< 0.25. The expert opinion and modification situation finally formed 5 primary indicators, 18 secondary indicators and 47 tertiary indicators. Conclusions The evaluation index system of core competency of nuclear medicine nurses is highly scientific and reliable, which provides a reference for core competency training of nurses in nuclear medicine.

Objective:To visualize and analyze the literature related to nurses′ psychological contract at home and abroad by CiteSpace software, discuss the development trend, and to provide reference for subsequent research.Methods:Literature related to nurses′ psychological contract collected by China National Knowledge Infrastructure and Web of Science from the establishment of the database to August 31, 2023 were retrieved. CiteSpace software was used to visually process the authors, institutions, keywords, publication trends and other types of nodes. Combined with the visualization map, the research status and hot trends of nurses′ psychological contract were analyzed.Results:A total of 175 articles in English and 126 articles in Chinese were included. The annual publication volume showed a zigzag upward trend. Chen Furong′s team published the most Chinese literature, while Rodwell J′s team published the most English literature. Shanxi Medical University and Monash University were the research institutions with the largest number of publications in Chinese and English respectively. Domestic research hotspots mainly focused on 5 directions: the status quo investigation, influence factors, intervention strategies, the impact on performance behavior, the content and structure of nurses′ psychological contract. Foreign research hotspots mainly focused on 3 directions: the influence factors, intervention strategies and the impact on performance behavior.Conclusions:The overall number of papers published in the field of nurses′psychological contract research at home and abroad is small, and the depth and breadth of the research are far from enough. The cooperation between authors and institutions should be strengthened, the research direction should be more diversified, and the mediation effect analysis and influence mechanism research of psychological contract should be paid attention to, so as to construct a multipath nurses′psychological contract system complied with national condition.

Objective? To design a satisfaction scale on nutrition support nursing service for inpatients, and establish a structural equation model of inpatient satisfaction with nutrition support nursing service in central city area to test the scale, so as to construct a tool for evaluating the satisfaction with nutrition support nursing service. Methods? This study selected 18 indicators affecting the satisfaction with nutrition support nursing services of inpatients based on the European Customer Satisfaction Index (ECSI), the American Customer Satisfaction Index (ACSI) Model, and the China Customer Satisfaction Index Model. From September to December of 2017, a convenience sampling investigation was carried out among the inpatients receiving nutritional support in a Class?Ⅲ Grade A medical institution. Through factor analysis, the 18 impact indicators were categorized into 6 dimensions, namely, perception of nutrition support nursing quality, nursing expectations, nutrient support nursing brands, nutrient support nursing service satisfaction, patient nutrient support nursing loyalty, patient nutrient support nursing complaints. Results? A structural equation model for satisfaction of nursing support services for inpatients was constructed, and the rationality of the 6 dimensions was verified. The Cronbach's α indexes of the 6 dimensions were all equal or greater than 0.80. KMO test coefficient was 0.745. Bartlett spherical test results showed χ2=3 402.132 (P＜0.01). The reasonableness of the six dimensions was verified, and the fitting effect of the model was good (χ2/df=1.416, RMS of residual=0.030, goodness of fit index=0.945, adjusting goodness of fit index=0.927, standard fitting index=0.947, value-added fitting index=0.984, comparing fitting index=0.984, root mean square of approximate error=0.035). Conclusions? With this model, nurse managers can identify the factors affecting the satisfaction of patients receiving nutritional support, and propose continuous improvement strategies that will help improve the effectiveness of nursing services, and improve patient satisfaction with inpatient nutritional support, so as to provide reference for the research of satisfaction model for inpatients.