The objective of this study is to determine the prevalence of thyroid
dysfunction in Major Depressive Disorder and the factors that were associated
with the severity of MDD. Methods: A total of 140 major depressive disorder
patients researched are subjected for blood sampling to determine the blood
thyroid abnormalities. The severity of illness of MDD was determined by the
duration of illness, frequency of admission/ suicidal attempts, and the Hamilton
rating scale for depression (HAM-D). Results: Thirty-one of the 140 patients had
thyroid dysfunction. There was no significant difference in the severity of illness
among patients with MDD between thyroid dysfunction and normal function
group (p=0.024). Conclusion: Patients with MDD had high prevalence of thyroid
dysfunction; however, the former had no correlation with later. ASEAN Journal
of Psychiatry, Vol. 18 (1): January – June 2017: XX XX.