1.Outcomes of percutaneous coronary intervention of coronary left main disease
Batmyagmar Khuyag ; Surenjav Chimed ; Lkhagvasuren Zundui
Mongolian Medical Sciences 2019;190(4):14-18
Introduction :
The left main (LM) bifurcational stenting is coronary high risk interventional procedure (CHIP) which
associated with various post procedural outcome.
Goal:
In this study, we aimed to describe current practice of coronary left main bifurcational stenting and
patient’s outcome in Mongolia.
Materials and Methods:
We selected 50 patients who gave informed consent and treated by left main bifurcational stent. All
the patients gave informed consent form which was approved by ethical committee of Mongolian
National University of Medical Sciences. Coronary stenosis was evaluated by Syntax score and
Medina classification. The 1 year survival rate was estimated using Kaplan-Meier estimation.
Results :
A total of 50 patients who received LM bifurcational stent were chosen (mean age 60±11, male
gender 78%). Mean syntax I score was 26.1±8.6 and mean Syntax II score was 44.7±6.2. Medina
110 type lesion was 46% (n=23), medina 111 type lesion was 36% (n=18), medina 100 type lesion
was 6% (n=3), medina 011 type lesion was 4% (n=2) and medina 010 type lesion was 8% (n=4).
The median degree of stenosis was 50% (IQR 30%; 90%) for LM, 90% (IQR 80%; 99%) for LAD and
0% (IQR 0%; 80%) for LCx. The final procedural success with final TIMI 3 flow was achieved in 44
patients (88%). All-cause mortality was occurred 5 patients during follow-up and survival rate at the
1 year was 82% (95% CI 66; 97).
Conclusion
The bifurcational stenting is acceptable treatment choice which has good survival for high risk patients
with LM bifurcational disease.
2.Impact of urgent and elective percutaneous coronary intervention on outcomes of patients with left main coronary artery bifurcational stenosis
Bum-Erdene Batbayar ; Oyunkhand Buyankhishig ; Gereltuya Choijiljav ; Surenjav Chimed ; Lkhagvasuren Zundui ; Batmyagmar Khuyag
Mongolian Medical Sciences 2021;198(4):33-39
Introduction:
Left main coronary artery (LMCA) is a large vessel which supplies the majority of left ventricle and
critical lesion at the bifurcation of LMCA can lead to life threatening condition. Therefore, percutaneous
coronary intervention (PCI) on LMCA bifurcational stenosis is considered as a complex high risk
indicated patient and procedure (CHIP).
Goal:
In this study, we investigated the impact of urgent and elective PCI on outcomes of patients with
LMCA bifurcational stenosis.
Materials and Methods:
Patients who underwent for urgent PCI due to acute myocardial infarction (AMI) or elective PCI due
to stable coronary artery disease (CAD) for their LMCA bifurcational stenosis. Any lesion with >50%
stenosis on coronary angiography was considered as a critical stenosis. LMCA bifurcational stenosis
was evaluated by Medina classification. Difference between urgent and elective PCI group were
compared by independent sample t-test and chi-square test. Association between treatment strategy
(urgent or elective PCI) and prognosis were evaluated by Cox proportional hazard regression, and
survival rate was evaluated by Kaplan-Meier methods. Ethical approval was taken from the ethical
committee of the Health Science University of Medical Sciences (№30/1А) in June 12, 2012.
Results:
A total of 82 patients with LMCA bifurcational stenosis were included (mean age 62±11, male 76.8%)
and 14 of them underwent urgent PCI due to AMI and 68 of had elective PCI due to stable CAD.
Patients who underwent urgent PCI had significantly higher 30-day mortality (1.5% vs. 21.4%, p<0.05)
and all-cause mortality (7.4% vs. 35.7%, p<0.003) compared to the elective PCI group. Urgent PCI
for LMCA bifurcational stenosis due to AMI was associated with increased risk of death (HR=3.63, 95% CI 1.02-12.9, p<0.05). Kaplan-Meier estimation showed that patients in the urgent PCI group
had significantly lower survival compared to the elective PCI group.
Conclusion
Unanticipated urgent PCI for patients with LMCA bifurcational stenosis due to AMI is associated with
higher risk of short and long-term mortality. Patients who underwent urgent PCI for LMCA bifurcational
stenosis had significantly lower survival compared to elective PCI group.
3.The results of intravascular ultrasound guided percutaneous coronary intervention in patients with atherosclerotic coronary artery disease
Erdembileg Dandar ; Oyunkhand Buyankhishig ; Chingun Batmyagmar ; Bum-Erdene Batbayar ; Gereltuya Choijiljav ; Ankhbayar Lundendorj ; Munkhbat Batmunkh ; Surenjav Chimed ; Batmyagmar Khuyag
Mongolian Medical Sciences 2024;210(4):35-44
Introduction :
Intravascular ultrasound (IVUS) is an advanced technology used to guide percutaneous
coronary intervention (PCI) in patients with stable coronary artery disease (CAD).
Goal:
This study aims to describe the first successful implementation of IVUS in patients with
stable CAD in Mongolia.
Materials and Methods :
Patients with CAD who underwent either CAG or IVUS-guided PCI were prospectively
selected. All patients provided informed consent, which was approved by the Ethical
Committee of the Ministry of Health of Mongolia (March 17, 2023, №23/014). For patients who underwent CAG-guided PCI, stent deployment was performed under conventional
CAG guidance, while stent implantation was performed under IVUS guidance in patients
who underwent IVUS-guided PCI. Stent restenosis at 1-year follow-up was selected as
the primary endpoint. The differences between the CAG-guided PCI and IVUS-guided
PCI groups were compared using independent sample t-tests and chi-square tests. The
association between treatment strategy (CAG-guided PCI vs. IVUS-guided PCI) and all
cause restenosis (the study endpoint) was analyzed.
Results:
A total of 51 patients with stable coronary artery disease (CAD) who underwent coronary
angiography CAG guided PCI and intravascular ultrasound (IVUS)-guided PCI were included
in the present study. The mean age was 63±9.44 years, with 88.2% male (n=45). In the
IVUS-guided PCI group, the minimal lumen area (mm²) was 4.46±1.1, and after stenting, the
minimal stent area was 8.59±0.5, showing a statistically significant difference (p<0.001). The
stent restenosis rate at 1-year follow-up in the CAG-guided PCI group and the IVUS-guided
PCI group were 16% and 3.84%, respectively. The restenosis rate in the IVUS-guided PCI
group was lower than in the CAG-guided PCI group.
Conclusion
Complete expansion of the stent on the coronary artery wall is effective in improving long
term outcomes of PCI, and IVUS guided coronary artery intervention has better long-term
results compared to angiography-guided PCI group (96.1% vs 84%).