1.Test methods of visual alarm signal for medical alarm systems.
Chinese Journal of Medical Instrumentation 2014;38(3):219-221
This paper introduces several test methods of characteristics of alarm indicator lights which can be used in the medical alarm system to verify the compliance of YY 0709-2009. These methods include the direct measurement of the pulse current supply of the alarm signals, image analysing of a video and reception by photoelectric sensor. After the comparation of the advantages and disadvantages among these methods, this paper proposes a new method of signal reception. This method which used a silicon photocell as the sensor with light filter in its front, and amplified circuit in the output end then used an oscillograph as the reviewer, has resolved the testing difficulties of the flashing signal simulating by LCD, and can be applied to test the alarm indicator lights in any medical electrical equipment.
Clinical Alarms
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Equipment Design
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Signal Processing, Computer-Assisted
2.Toll-like receptor 4 signalling pathway in microglia and central nervous system injury
International Journal of Cerebrovascular Diseases 2011;19(12):944-947
The mechanism of central nervous system injury is complex.Microglia cells participate in a variety of central nervous system diseases and damage processes.Toll-like receptor 4 (TLR4) mediates the microglial activation and the expression of inflammatory cytokines.It is one of the important receptor proteins for microglia cells performing their functions.This article briefly introduces the role of TLR4 signal pathway in the central nervous system injury.
3.Wireless human body communication technology.
Journal of Biomedical Engineering 2014;31(6):1389-1393
The Wireless Body Area Network (WBAN) is a key part of the wearable monitoring technologies, which has many communication technologies to choose from, like Bluetooth, ZigBee, Ultra Wideband, and Wireless Human Body Communication (WHBC). As for the WHBC developed in recent years, it is worthy to be further studied. The WHBC has a strong momentum of growth and a natural advantage in the formation of WBAN. In this paper, we first briefly describe the technical background of WHBC, then introduce theoretical model of human-channel communication and digital transmission machine based on human channel. And finally we analyze various of the interference of the WHBC and show the AFH (Adaptive Frequency Hopping) technology which can effectively deal with the interference.
Computer Communication Networks
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Humans
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Models, Theoretical
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Wireless Technology
4.Influence of early rehabilitative exercise in patients with myocardial infarction
Chinese Journal of Tissue Engineering Research 2006;10(24):164-166
BACKGROUND: In treatment of traditional acute myocardial infarction,patients were required to lie on the bed resting for 1-4 weeks. Recently research showed that early rehabilitation exercise in myocardial infarction patients could ameliorate the reservation of cardio function, increase exercise tolerance, augment myocardial hemoperfusion, decrease myocardial ischemia and reduce the anxious and depressive emotion.OBJECTIVE: To observe the influence of early rehabilitation movement on activity of daily living, duration of hospital stay, mean hospitalized cost,incidence rate of arrhythmia and recurrence rate of myocardial infarction in two years.DESIGN: Non-randomized concurrent control analysis.SETTING: Beijing Tiantan Hospital.PARTICIPANTS: Totally 80 patients with acute myocardial infarction,who were hospitalized at Department of Circulation, Beijing Tiantan Hospital from August 2002 to October 2003, were enrolled. They were all at most 70 years old with stable pathogenetic condition. Left ventricular ejection fraction (LVEF) was over 35%. They were not combined with severe hypertension, severe pulmonary disease, nerve and disease of locomotor system.METHODS: The selected cases based on patients' will were assigned into two groups (n=40), ①early rehabilitation group: They were treated with routine drugs, absolute bed rest for 24 hours. At day 2 the head stock was rose about 30°to do passive exercise of extremity joint. At days 3-5, the patients sat on the bed, 3 times per day. At days 6-7,the patients stood at bedside, 3 times per day. At days 8-9, the patients moved joints of extremities at bedside and walked slowly in room. At days 10-14, the patients exercised walking. If there were angina pectoris attacks, serious cardiac arrhythmias or dyspneic respiration, etc., the movement should be suspended or the exercise intensity came back to that in the former stage. ②Absolute bed rest group: The patients were absolute bed rest, and only treated with routine drug without any rehabilitation training.MAIN OUTCOME MEASURES: Barthel index (full mark was 100 points, and < 60 points represented unable self-care) was used to assess activity of daily living of patients. Mean duration of hospital stay, mean hospitalized cost, incidence rate of arrhythmia and recurrence rate of my ocardial infarction in two years were compared between the two groups.RESULTS: A total of 80 patients that conducted the therapy and follow up were involved in the result analysis. ①Mean duration of hospital stay and mean hospitalized cost in the early rehabilitation group were less than those in the absolute bed rest group (17.1 days vs 24.5 days; 9 021.23 yuan vs 12 383.45 yuan; P < 0.05). ②Barthel index: There was insignificant difference before treatment between the two groups. It was significantly higher in the early rehabilitation group than that in the absolute bed rest group before discharge (81.43±13.57,70.68±11.48,P < 0.05). ③Six and seven patients had the onset of arrhythmia in the early rehabilitation group and the absolute bed rest group, respectively. ④Follow-up observation was performed for two years. The recurrence rate of myocardial infarction in the early rehabilitation group (5% ,2/40) was obviously lower than that in the absolute bed rest group (22 %,9/40).CONCLUSION: The early rehabilitation training is of benefit to elevate activity of daily living of myocardial infarction patients, reduce mean duration of hospital stay and mean hospitalized cost and decrease recurrence rate.
5.Modified sliding myofascial flap of the rectus abdominus muscles for the closure of huge planned abdominal hernia
Chinese Journal of Digestive Surgery 2013;(7):524-526
Abdominal increment is applied to patients with abdominal compartment syndrome (ACS) after severe trauma,while for some patients,intra-abdominal volume increment could not close the fascia within the primary stage.For theses patients,abdominal wound skin grafting was conducted,and the planned hernia was formed.Planned abdominal hernia developed over time,and finally huge incisional hernia was formed.This article described a modified sliding myofascial flap of the rectus abdominus muscles for definitive abdominal wall reconstruction for a patient with huge planned abdominal hernia,and a good curative effect was obtained.
6.Progress of research On genetic markers of Oncomelania hupensis
Chinese Journal of Schistosomiasis Control 2010;22(1):90-95
With the progress of the genetics and the molecular biology and biotechnology,the development of genetic markers of Oncomelania hupensis also has gone through the course from indirect methods to direct methods and from sketchy results to precise results.The paper reviews the progress of research on genetic markers of O.hupensis.
7.Effect of one-time exhaustive exercise on individual' s mood states
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(10):929-931
Objective To study the changes of the mood states at different time point of one-time exhaustive exercise.Methods16 participants were tested by POMS at the moments before,at,after recovery and after recovery 20 min of one-time exhaustive exercise.Results The scores of the 7 subscales got by 4 measures were used for one-way repeated measures analysis of variance.The results were showed that tension subscale scores (F (3.45) =0.335,P>0.05,ES =0.022),anger subscale scores (F(3.45) =3.683,P>0.05,ES =0.197),fatigue subscale scores (F(3.45 =0.863,P>0.05,ES =0.054),depression subscale scores (F(3.45) =1.905,P> 0.05,ES =0.113 ),confusion subscale scores (F( 3.45) =0.601,P > 0.05,ES =0.039 ) and self-esteem subscale scores (F(3.45) =2.804,P > 0.05,ES =0.157 ) had no significant differences,but vigor subscale scores increased significantly (F(3.45) =8.778,P < 0.01,ES =0.369).Conclusion One-time exhaustive exercises enhanced individual' s positive mood states.
8.The diagnostic value of high frequency color doppler ultrasound in acute appendicitis
Chinese Journal of Primary Medicine and Pharmacy 2011;18(23):3200-3201
Objective To study the diagnostic value of high frequency color doppler ultrasound acute appendicitis.Methods 98 patients with symptoms of acute appendicitis were selected,the application of Logiq 9 color Doppler ultrasonic diagnostic apparatus,a frequency of 7 ~ 10.0MHz was wsed.The McBurney point as well as around the right lower quadrant tenderness of rebound pain at the obvious on the miter,slitting,transverse scanning.Combined with color Doppler flow imaging to understand the flow conditions.After diagnosis of the patients with operation of diagnosis and treatment,the histopathology of the final diagnosis with ultrasound diagnosis results were compared,and through statistical analysis,identifying all patients with the rate of misdiagnosis,missed diagnosis rate,positive rate.Results The exploration and operation pathology diagnosis results contrast,all 98 patients,diagnosed in 95 patients,the positive rate was 96.9% ;1 cases were missed diagnosis,misdiagnosis missed diagnosis rate was 1% ;in 2 cases,the misdiagnosis rate was 2%.Conclusion High frequency color doppler acoustic in the diagnosis of acute appendicitis diagnosis rate was high,with clinical practical value.
9.The clinical value of Tei index in the evaluation of left ventricular function of diabetic patients with normal LVEF
Chinese Journal of Primary Medicine and Pharmacy 2013;20(22):3388-3390
Objective To observe the value of myocardial performance index (Tei index) in evaluating the left ventricular function in diabetic patients with normal left ventricular ejection fraction (LVEF),and to investigate its correlation with plasma N-terminal pro-brain natriuretic peptide (NT-proBNP).Methods 96 diabetic patients with normal LVEF were selected as the observation group,50 healthy persons were selected as control group.Left ventricular Tei index was measured by color Doppler ultrasound.The plasma NT-proBNP was detected.Results The Tei index,plasma level of NT-proBNP of the observation group were (0.49 ± 0.11),(397.6 ± 39.4) ng/L,those of the control group were (0.32 ± 0.07),(101.2 ± 18.4) ng/L,the differences between the two groups were statistically significant(t =11.357,1.992,all P < 0.05).There was significant positive correlation between Tei index and plasma NT-proBNP in the observation group(r =0.661,P < 0.05).Conclusion Combined determination of Tei index and plasma NT-proBNP can detect early myocardial damage in patients with diabetes mellitus.
10.Establishment of gastric cancer model in nude mice
International Journal of Surgery 2011;38(7):472-474
The establishment of animal model is fundamental to the experimental studies. It involves the selection of animals and cell lines, the determination of the number of cells and the option of the ways of transplant. Only when each production step is operated by following the occurrence and the development mechanism of the gastric cancer, can we simulate the process of growth of the gastric cancer in human body.Due to their congenital immune deficiency, the nude mice serve a better choice for the establishment of gastric cancer animal model. Beyond that, the cell lines selection and transplant way option also play important roles.