The concept of white matter dementia was first introduced by Filley in 1988.It was found following behavioral neurologica researches that patients with this type of dementia manifested the dysfunctions of sustained attention,memory retrievial,frontal lobe and visualspatial function.They also had psychiatric manifestations but language and extrapyramidal function remained normal.10 diseases of white matter disorders are listed for understanding the clinical characteristics of this type of dementia.

Objective To explore the effect of the gargled astragalus water decoction as the adjuvant therapy on serum CD14, TNF-αand IL-8 levels in patients with acute suppurative pulpitis.Methods 42 patients who were diagnosed with acute suppurative pulpitis in our hospital were collected. All patients were randomly divided into experimental group and control group, 21 cases in each group.Patients in the control group received conventional therapy, while patients in the experimental group were given the additional adjuvant therapy that gargled with astragalus water decoction.After the treatment, the serum levels of CD14,TNF-αand IL-8 were detected in all patients.Results After treatment, the serum levels of CD14, TNF-αand IL-8 in the experimental group were statistically lower than control group ( P<0.05 ) .Conclusion The gargled with astragalus water decoction as the adjuvant therapy could significantly reduce the serum CD14,TNF-αand IL-8 levels in patients with acute suppurative pulpitis,and it could obviously relieve inflammation.

Objective To investigate the compassion fatigue and stress status and the relationship between them of nurses working in secondary hospitals of integrated areas of urban and rural places, and explore the social factors that influence the compassion fatigue and stress status. Methods 378 nurses from secondary hospitals in urban-rural integrated area were selected as samples in Nanjing. Paramedic′s Compassion Fatigue Scale and Chinese Nurse Stressor Questionnaire were adopted to develop the survey. Results The nurse compassion fatigue score was (15.9 ± 1.83) points; Stress status score was (86.18 ± 19.96) points. Urban-rural fringe secondary hospital nurse compassion fatigue status was positively associated with the pressure (r=0.218, P<0.01), and loss of enthusiasm, nervousness, loss of ability to doubt, and morale were on the medical staff work pressure had significant influence (P<0.05). Conclusions The nurse compassion fatigue and stress level were in the medium level; Nursing managers should pay more attention to the psychological health level of the nurses, increase nurses' enthusiasm, alleviate the occupational stress of nurses caused by compassion fatigue.

Many malignant tumors, most commonly small cell lung cancer, merge with syndrome of inappropriate secretion of antidi-uretic hormone (SIADH). SIADH is caused by the neuroendocrine function of tumor cells or is a side effect of chemotherapeutics. As a chemotherapeutic side effect, SIADH presents as hyponatremia. Therapy for SIADH includes both treatment for primary diseases and hyponatremia. Given that SIADH-induced hyponatremia aggravates the prognosis and shortens the survival time of patients with malig-nant tumors, SIADH is an independent risk factor for prognosis. Therefore, the early diagnosis, monitoring, and treatment of SIADH will improve the prognosis of patients with malignant tumors.

The Balanced Scorecard,as a new strategic management tool,has been widely used in the performance evaluation of Chinese enterprise.This review discussed the application and potential problems of the Balanced Scorecard in the research performance management of the research universities.

Objective:To detect changes in mitochondrial membrane potential after sperm mother cell damage induced by bisphenol A by laser scanning confocal microscopy(LSCM) and underline its potential action mechanism.Methods: The cultured spermatogenic cells were divided into 3 groups, respectively. Then 0, 10μmol/L, 100μmol/L of Bisphenol A(BPA) were added into the culture, after 3 hours culture, fluorescence probe JC-1 was used to lable the three groups. The fluorescence intensity of JC-1 in mitochondrial was then detected by LSCM. LSCM software was used to analyze the fluorescence intensity. Change of the mitochondrial membrane potential was represented by the change of fluorescence colors (relative proportion of red and green fluorescence is commonly used to measure mitochondrial depolarization ratio). Results:The ratio between the red and green fluorescence in the control group, low dose group and high dose group had significant difference. Intracellular mitochondrial membrane potential of Bisphenol A treatment group was lower than that of the control group, while mitochondrial membrane potential of high dose group was lower than that of the low dose group. Conclusion: Bisphenol A could damage spermatocytes, and as the dose increased, the more serious the injury. The method could real-time monitor with high sensitivity the change of intracellular mitochondrial membrane potential.

OBJECTIVE:To establish a website platform for clinical pharmacists'online learning and communication and to promote the development of clinical pharmacy.METHODS:A MySQL database in remote server was established,and PHP dynamic web page program was applied to construct a website for clinical pharmacists.RESULTS:The website ran smoothly and fast and its maintenance is very convenient,which met clinical pharmacists' needs for the online learning and communication. CONCLUSIONS:The establishment of website platform is of significance for the online learning,information sharing and communication among clinical pharmacists in clinical pharmacy.

OBJECTIVE:To evaluate the economic efficacy of 6 therapeutic schemes for hepatic lesions induced by chemotherapeutic drugs. METHODS: A total of 269 malignant tumor patients complicating hepatic lesion because of using of chemotherapeutic drugs were randomly divided into 6 groups (A, B, C, D, E and F) to be treated with Reduced Glutathione Sodium for Injection, Diammonium Glycyrrhizinate Injection, Compound Glycyrrhizin Injection, Polyene Phosphatidylcholine Injection, Compound Diisopropylamine Dichloroacetate Injection, Compound Ammonium Glycyrrhetate Injection, respectively. The curative effects were recorded and the cost-effectiveness analysis was conducted. RESULTS: In A, B, C, D, E and F groups, the effective rates were 91.67%, 75.00%, 86.05%, 84.78%, 87.50% and 85.42%, respectively, the costs were 798.28 yuan, 311.08 yuan, 859.88 yuan, 918.68 yuan, 1 092.28 yuan and 1 319.08 yuan, respectively, and the cost-effectiveness ratios were: 870.82, 414.77, 999.28, 1 083.60, 1 248.32 and 1 544.23, respectively. The incremental cost-effectiveness ratios for A, C, D, E, F groups as against group B were 2 922.62, 4 966.52, 6 212.68, 6 249.60 and 9 673.70, respectively. CONCLUSION: Group A was proved to be the safe, effective and economical therapeutic scheme for hepatic lesions induced by chemotherapeutic drugs.

0.05),but there was a significantly difference in parameters between the nasal obstruction side and the no obstruction side in patients with nose deformities (P0.05). CONCLUSION The results indicate that acoustic rhinometry has great value in evaluation of patients with nasal deformities before operation and can provide clinical value for the evaluation of nasal function and geometrical structure.

OBJECTIVE:To improve the medication compliance of diabetic patients.METHODS:A questionnaire survey was conducted on the spot with Excel used for data input,and the data were analyzed statistically using chi-square test in SPSS13.0 software.RESULTS & CONCLUSION:The medication compliance rate of the 193 diabetic patients was low at 47.15%.The diabtes patients' medication compliance can be improved through regular consultation,recognition of disease,knowledge on drugs and better pharmaceutical care.