Objective To analyze the clinical feature of 17 cases children toxic hepatitis type of mushroom poisoning ,investigate toxic hepatitis type mushroom poisoning treatment .Methods 17 children with mushroom poi-soning toxic hepatitis were chosen as the objects of study ,who were retrospectively analyzed .Results 17 cases of tox-ic hepatitis type of mushroom poisoning in children were dealed with drug treatment ,cured 12 cases,5 deaths,the cure rate of 70.6%;all patients,red blood cells,white blood cells and hemoglobin were normal ,7 cases of blood in the stool,6 cases of hematuria .All patients transaminase liver function tests and jaundice index were significantly in-creased,electrocardiogram showed sinus bradycardia 8 cases, sinus tachycardia 2 cases,1 case of renal damage. Conclusion Toxic hepatitis type mushroom poisoning mortality ,the elimination of toxins is where the key to have a certain effect of plasma exchange therapy ,liver transplantation is the most effective means of treatment ,especially gas-trointestinal bleeding with liver damage ,should be carried out as soon as possible based treatment plasmapheresis .

Objective To explore the effect of the Blood Circulation Punching Apparatus in the blood pressure of the spinal cord injury(SCI) patient with hypotension.Methods 28 patients with spinal cord injury were divided into two groups, the treatment group and the control group. The blood pressure was recorded before and after treatment, then changes of the blood pressure were compared.Results Both diastolic and systolic blood pressure increased in two groups（P<0.05）. Though no significant difference was found between two groups before treatment, significant difference was found between two groups after treatment（P<0.05）.Conclusion The Blood Circulation Punching Apparatus could improve the blood pressure of SCI patients with hypotension significantly.

由于近期地震,在ICU内多脏器功能衰竭的发生率与病死率极高,对高危患者进行严密监测,能早诊断、早治疗,积极护理,阻断由单一受累脏器向多脏器发展的病理生理过程,从而降低病死率。肺部改变、肾改变、脑改变、心血管改变、胃肠道改变、肝脏改变、弥散性血管内凝血是导致多脏器功能衰竭的常见原因。脏器衰竭越多,病死率越高,2个器官衰竭病死率为30%,3个达70%,4个为90%～100%。严密的观察监测及积极护理,是维持良好的呼吸、循环、胃肠功能、肾功能,能使器官受损的严重性和数目降到最低限度。

ObjectiveTo compare the effects of discharging sputum with machine vibration and percussion on back in patients with spinal cord injury (SCI) complicated with lung infection.Methods33 patients were divided into machine group (n=18, discharging sputum with machine vibration) and percussion group (n=15, discharging sputum with percussion on back). Then the auscultation of lungs, change of Sp2, abatement time of fever, white blood cells count and X-ray results of chest were compared to estimate the effect of discharging sputum.ResultsThere was a significant difference in the auscultation of lungs between the two groups ( P<0.05), while no significant difference was founded in the SpO2 between two groups after sputum discharged ( P>0.05). The abatement time of fever was shortened significantly in the machine group after treatment( P<0.05). The X-ray results improved significantly in the machine group, compared with percussion group ( P< 0.05).ConclusionThe effect of discharging sputum with machine vibration is better than percussion on back.

Drug Therapy, Combination ; Echinocandins ; administration & dosage ; therapeutic use ; Humans ; Invasive Pulmonary Aspergillosis ; complications ; drug therapy ; Lipopeptides ; Liver Failure ; complications ; drug therapy ; microbiology ; Male ; Middle Aged ; Voriconazole ; administration & dosage ; therapeutic use

Objective To analyze the relationship between alexithymia and patients' satisfaction under the condition of good quality in the esthetic characters. Methods 211 patients requiring single anterior tooth restoration were treated with all ceramic crowns which were assessed by the good and moderate degrees. Patients received 20-item Toronto Alexithymia Scale (TAS-20) and a visual analogue scale assessing patients' satisfaction (VAS). Chi-squared analysis, correlation analysis and the general linear modeling procedure were calculated for TAS total and factors scores according to age, gender and dichotomized satisfaction. Results 85. 3% patients belonged to the high satisfaction group(VAS scores 80 or higher) and 7.1% reported alexithymia ( total score 61 or higher). No difference across gender was observed in the prevalence of alexithymia and satisfaction. Age was correlated with the TAS scores ( r=0.629) and satisfaction scores ( r= -0.429). According to dichotomized satisfaction,TAS total and factor 1&2 scores were significantly different. When adjusting for the effect of age,the association was existed between TAS scores and san'sfaction( r= -0.68). Conclusion Alexithymia has effect on dental satisfaction.

Objective To analyze post-traumatic growth of Chinese caregivers of dementia patients and to explore the caregivers′positive and potential energy, in order to formulate more perfect nursing intervention measures. Method Useing phenomenological method of qualitative research in selecting 6 dementia caregivers in-depth interviews to understand possible posttraumatic growth. Result Five major themes were found: changes in individual cognitive, changes in relations with others, promote their children′s education, reflections and concerns on status of pension-related changes in philosophy of life. Conclusions Dementia caregivers also have the positive performance of posttraumatic growth, in addition to the negative experience. Clinical nurses should actively explore the potential and power from the growth perspective. This is conducive to the caregivers with more health caring for life, so as to improve the quality of care, and ultimately improve the quality of life.

Objective To investigate the changes in plasma levels of angiotensin Ⅱ, endothelin-1 and blood pressure fluctuation during light-dark alterative period in sinoaortic denervated (SAD) rats. Methods Seventy-two male Sprague-Dawley rats underwent SAD or sham operation at the age of 12 weeks. Twenty-four-hour blood pressure and blood pressure variability (BPV) were measured in conscious, unrestrained rats 4 weeks after operation. Rats were housed in a 12 h light/12 h dark cycle (LD 12:12) for at least 10 days, then the blood samples were taken every 4 h. The plasma levels of angiotensin Ⅱ and endothelin-1 were assayed by radioimmunoassay (RIA). Results No significant difference in SBP or DBP between SAD and sham-operated rats was found. Compared with sham-operated rats, SAD rats had greater SBPV and DBPV over 24 hours (SBPV: 13.8?4.2 vs control: 6.4?1.1, DBPV:11.5?3.1 vs control: 5.3?0.8 mm Hg, all P

Thrombelastography (TEG) is an image presenting the viscoelasticity changes of blood clot in the process of blood clotting,consequently reflecting the ability of blood clotting and fibrinolysis.TEG is increasingly used in the field of guiding intraoperative blood transfusion,monitoring the Blood coagulation function,treating trauma patient,and monitoring the blood coagulation and fibrinolytic function of a variety of diseases,due to its rapid and accurate results.We discuss the clinical applications progress of TEG in this article.

OBJECTIVE:To establish a method for the simultaneous determination of psoralen,isopsoralen,epimedin B,epi-medin C and icariin in Chanlong dingchuan mixture. METHODS:HPLC was performed on the column of Welch Materials C18 with mobile phase of acetonitrile- methanol(1∶1,V/V)-water(gradient elution)at a flow rate of 0.9 ml/min,the detection wavelength was 246 nm(psoralen,isopsoralen)and 270 nm(epimedin B,epimedin C and icariin),column temperature was 30 ℃,injection volume was 20 μl. RESULTS:The linear range was 8.24-164.80 μg/ml for psoralen(r=0.999 7),5.15-103.00 μg/ml for isopso-ralen(r=0.999 3),4.06-81.20 μg/ml for epimedin B(r=0.999 6),5.88-117.60 μg/ml for epimedin C(r=0.999 5)and 4.90-98.00μg/ml for icariin(r=0.999 8);the limits of quantitation were 0.385 μg/ml,0.179 μg/ml ,0.124 μg/ml,0.218 μg/ml and 0.348 μg/ml, limits of detection were 0.127μg/ml,0.059μg/ml ,0.041μg/ml,0.072μg/ml and 0.115μg/ml;RSDs of precision,stability and re-producibility tests were lower than 2.0%;recoveries were 97.93%-100.06%(RSD=0.80%,n=6),96.91%-100.16%(RSD=1.37%,n=6),96.95%-99.63%(RSD=0.98%,n=6),96.69%-99.33%(RSD=1.03%,n=6) and 96.76%-98.53%(RSD=0.70%,n=6),respectively. CONCLUSIONS:The method is simple and reliable,and suitable for the simultaneous determination of psoralen,isopsoralen,epimedin B,epimedin C and icariin in Chanlong dingchuan mixture.