Objective To observe the influence of complicated infections on functional outcome of patients with stroke.Methods Two hundred and twenty-five stroke patiens confirmed by cranial CT scan or MR were prospectively divided into non-infection (145 cases) and infection (80 cases) groups. The body temperature of all the patients was recorded on admission and during hospitalization. the National Institutes of Health Stroke Scale(NIHSS), Barthel Index(BI) and modified Rankin Scale(mRS) were documented in all the cases. The difference in functioual outcome between the two groups was analyzed.Results The maximun body temperature of infection group was higher than that of the non-infection during hospitalization(P＜0.01). The funtional outcome of the patients complicated with infections was significantly worse than that of the cases without infections assessed by BI(P＜0.01), mRS(P＜0.01) and NIHSS(P＜0.01).Conclusion Infection of the stroke patients influenceed functional outcome and the prognosis.