1.Assessing Biomarkers On Exposure, Effects And Susceptibility For Environmental And Occupational Exposure Of Various Range Of Benzene
Noor Fatihah MF ; Suhaili A ; Juliana J
Malaysian Journal of Public Health Medicine 2017;2017(Special Volume (1)):7-18
Background: Benzene is primarily routed by inhalation which highly sensitive to blood parameters as bone marrow is their target organ. The ability of benzene even in low exposure levels may induce human bone marrow suppression resulting in blood diseases such as leukopenia, anemia, thrombocytopenia, aplastic anemia, and pancytopenia. In the occupational setting, the most common benzene-exposed workers are from the petrochemical industries and petrol distribution such as gasoline pumps. Benzene also generated primarily by mobile exhaust and some from various of anthropogenic sources at environmental atmosphere and occupationally exposed in the policemen traffic, taxi and bus drivers, and street vendors in long-length time with low concentration exposure. Methodology: This paper reviewed published articles on biomarkers exposure, effects and susceptibility as the useful tools for benzene exposure assessment in the occupational and environmental setting. Data from previous epidemiological studies relevant to benzene exposure in various occupational and environmental setting is also summarized. Results: Based on these analyses, the findings agreed that these biomarkers are could suggest in linking the benzene exposure with possible adverse health effects. The biological monitoring used in epidemiological studies is useful in providing an understanding of activation and detoxification of benzene in both the occupational and general population as they are exposed to wide range of benzene concentration. Conclusion. The biomarkers of exposure, effects, and susceptibility utilized for benzene exposure assessment are valid tools in determining the greatest potential risk as well as an early biological effect which then caused a related specific disease.
benzene exposure
;
biomarkers
;
genetic polymorphisms and environmental and occupational population
2.Assessing Biomarkers On Exposure, Effects And Susceptibility For Environmental And Occupational Exposure Of Various Range Of Benzene
Noor Fatihah MF ; Suhaili A ; Juliana J
Malaysian Journal of Public Health Medicine 2017;Special Volume(1):7-18
Background: Benzene is primarily routed by inhalation which highly sensitive to blood parameters as bone marrow is their target organ. The ability of benzene even in low exposure levels may induce human bone marrow suppression resulting in blood diseases such as leukopenia, anemia, thrombocytopenia, aplastic anemia, and pancytopenia. In the occupational setting, the most common benzene-exposed workers are from the petrochemical industries and petrol distribution such as gasoline pumps. Benzene also generated primarily by mobile exhaust and some from various of anthropogenic sources at environmental atmosphere and occupationally exposed in the policemen traffic, taxi and bus drivers, and street vendors in long-length time with low concentration exposure. Methodology: This paper reviewed published articles on biomarkers exposure, effects and susceptibility as the useful tools for benzene exposure assessment in the occupational and environ-mental setting. Data from previous epidemiological studies relevant to benzene exposure in various occupational and en-vironmental setting is also summarized. Results: Based on these analyses, the findings agreed that these biomarkers are could suggest in linking the benzene exposure with possible adverse health effects. The biological monitoring used in epi-demiological studies is useful in providing an understanding of activation and detoxification of benzene in both the occu-pational and general population as they are exposed to wide range of benzene concentration. Conclusion. The biomarkers of exposure, effects, and susceptibility utilized for benzene exposure assessment are valid tools in determining the greatest potential risk as well as an early biological effect which then caused a related specific disease.
3.Laboratory contact and topical evaluations of household disinfectants against house dust mites Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acari:
Suhaili, Z.A. ; Mariana, A. ; Ho, T.M. ; Azima, L.H.
Tropical Biomedicine 2016;33(4):847-852
The contact and topical activity of two household disinfectants containing
chloroxylenol and benzyl chlorophenol against, Dermatophagoides pteronyssinus and
Dermatophagoides farinae mites were evaluated in the laboratory. For contact activity, 30
adult mites were placed for 24 hrs on Whatman No. 1 filter paper impregnated with disinfectant.
For topical activity, each disinfectant was directly applied to individual body of all 30 dust
mites and observed for 24hrs. All treatments were replicated 12 times. Chloroxylenol
disinfectant was found to be more effective compared to benzyl chlorophenol disinfectant in
killing pyroglyphid mites.
4.Effect of a commercial air ionizer on dust mites Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acari:Pyroglyphidae) in the laboratory
Abidin Zainal Suhaili ; Ming Tze Ho
Asian Pacific Journal of Tropical Biomedicine 2012;(2):156-158
Objective:To investigate the short and long term efficacy of a commercial air ionizer in killing Dermatophagoides pteronyssinus (D. pteronyssinus) and Dermatophagoides farinae (D. farinae) mites. Methods: The effect of a commercial ionizer on D. pteronyssinus and D. farinae was evaluated in the laboratory, using a specially designed test. Mortality was assessed after 6, 16 and 24 hours for direct exposure and after 24, 36, 48, 60 and 72 hours for exposure in simulated mattress. New batches of mites were used for each exposure time. Results: LT50 for direct exposure of ionizer was 10 hours for D. pteronyssinus and 18 hours for D. farinae. The LT50 for exposure in simulated mattress was 132 hours or 5.5 days for D. pteronyssinus and 72 hours or 3 days for D. farinae. LT95 for direct exposure of ionizer was 36 hours for D. pteronyssinus and D. farinae. Meanwhile, the LT95 for exposure in simulated mattress was 956 hours or 39.8 days for D. pteronyssinus and 403 hours or 16.8 days for D. farinae. Conclusions:This study demonstrates the increasing mite mortalities with increasing exposure time of a commercial ionizer and suggests that negative ions produced by an ionizer kill dust mites and can be used to reduce natural mite populations on exposed surfaces such as floors, clothes, curtains, etc. However, there is reduced efficacy on mites inside stuffed materials as in mattresses and furniture.
5.A Ten Year Retrospective Review of Orbital Complications Secondary to Acute Sinusitis in Children
D N Pengiran Suhaili ; B S Goh ; B S Gendeh
The Medical Journal of Malaysia 2010;65(1):49-52
Acute sinusitis is most often a mild self-limiting disease.
However, it may progress into severe and life threatening
complications. One of the commonest being orbital
complication of which visual loss is a direct consequence. In this 10 year retrospective study, the nature of orbital
complication, clinical presentation and treatment modalities and outcome seen in children with acute sinusitis in a tertiary referral institute were reviewed. Of six patients, there was a case of preseptal cellulitis, 4 cases of subperiosteal abscess and one case of orbital abscess. Periorbital swelling was a common presenting feature. In 5 cases this was associated
with proptosis with one case of impending optic nerve
compression. The value of computed tomography and
opthalmological examination as a component in the
management plan is highlighted. All patients were treated
with intravenous antibiotics but evidence of abscess
collection warranted urgent surgical drainage in 5 patients, 3 being endoscopic drainage while external approach was done for the remaining 2 patients. Thus a child exhibiting orbital complication of acute sinusitis, prompt diagnosis and treatment is essential in obtaining the best outcome for the child.
6.Prevalence and Determinants of Smoking Behaviour among the Secondary School Teachers in Bangladesh
Md Mizanur Rahman ; Md Jahirul Karim ; Sk Akhtar Ahmad ; Mohd. Raili Suhaili
International Journal of Public Health Research 2011;-(Special issue):25-32
Despite country’s tobacco control law, cigarette smoking by the young people and the magnitude of nicotine dependence among the school personnel is alarming. To determine the prevalence of smoking and to examine the determinants of smoking behaviour among the secondary school teachers in Bangladesh. A two-stage cluster sampling was used with a selection of schools on
Probability Proportional to Enrolment (PPE) size followed by stratified random sampling of government and private schools and then all the teachers present on the day of the survey were selected for the study. The 66-item
questionnaire included smoking behaviour, knowledge, attitude, second-hand smoking, tobacco free school policy, cessation, media advertisement and curriculum related topics. Seven additional questions were included to assess
the socio-demographic characteristics of the teachers. Data analysis was performed using SPSS 17 software. A total of 60 schools were selected with school response rate of 98.3%. An anonymous self-administered questionnaire was filled in by all teachers present at the day of the survey. The sample consisted of 559 teachers with response rate of 99.5%. The prevalence of smoking was 17% (95% CI: 14%, 20.4). About half of the teachers (48.4%) smoke daily followed by 25.3% smoke 1-2 days in last 30 days. The mean duration smoking of was 13.7(95% CI: 11.6, 15.9) years. Logistic regression analysis revealed that male teachers smoke 37.46(95% CI: 5.078, 276.432) times higher than their female counterparts. The graduate teachers were 2.179(95% 1.209, 3.926) times more likely to be smoke than master’s degree holder teachers. Smoking by friends appeared to be the strongest predictor for teachers smoking behaviour (OR 4.789, 95% CI: 1.757, 13.050). However, no statistically significant association was found between type of school, second-hand smoking and curriculum related factors and smoking behaviour of the teachers (p>0.05). Prevalence of smoking among the teachers is high in Bangladesh. Effective smoking prevention program should take into account within the dominant of socio-environmental influence to reduce smoking behaviour. The school curriculum items had less impact in preventing smoking behaviour.
Smoking
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Behavior
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Faculty
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Bangladesh
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Prevalence
7.Public Health Nursing in 1Care
Safurah Jaafar ; Kamaliah Mohd Noh ; Mohd Raili Suhaili ; Andrew Kiyu ; Flora Ong ; Margareth Wong
International Journal of Public Health Research 2011;-(Special issue):1-8
Public health nursing is a specialized nursing combining both nursing and public health principles with the primary focus of improving the health of the whole community rather than just an individual. Its documented history started in the 1800s and has evolved from home visiting to the varied settings that public health nurses find themselves working in as members of public health teams in clinics, schools, workplaces and government health departments.Public health nursing has been a critical component of the country’s health care system, uplifting of the health status of Malaysians and playing a dominant role in the fight against communicable diseases, and is set to face the challenges of the 21st century with public health nurses practising to the full capacity of their training in a restructured Malaysian health system – 1Care for 1Malaysia. The health sector reform allows for optimisation of scarce health care resources to deliver expansion of quality services based on needs, appropriateness, equity &allocative efficiency. The proposed model will be better than the current system, preserving the strengths of the current system but able to respond to increasing population health needs and expectations. There will be increased autonomy for healthcare providers with incentives in place for greater
performance. Some of the implications of reform include allowing public- private integration, a slimmer
Ministry of Health with a stronger governance role, enhancing the gatekeeping role of the primary care
providers and the autonomous management of the public healthcare providers. In this restructured health
system, the roles of the public health nurses are no less important than in the current one. In fact, with the
increasing emphasis placed on prevention and primary care as the hub of community care with nurses as part of
the primary care team delivering continuous comprehensive person-centered care,public health nurses in the
future will be able to meet the challenge of refocusing on the true mission of public health: to look at the health
problems of a community as a whole and work with the community in alleviating those problems by applying
the nursing process to improve health, not just as providers of personal care only.
Public Health Nursing
8.Isolation of Legionella pneumophila from hospital cooling towers in Johor, Malaysia.
B H Abdul Samad ; M R Suhaili ; N Baba ; G Rajasekaran
The Medical journal of Malaysia 2004;59(3):297-304
Water-based cooling towers and their water supply at two hospitals in Johor were surveyed for the presence Legionella pneumophila. L. pneumophila were grown from 19 (76%) out of 25 collected water samples. One hospital cooling tower was contaminated with L. pneumophila serogroup 1.
cooling
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Legionella pneumophila
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Hospitals
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L
;
Need for isolation
9.Acaricidal activity of Cymbopogon citratus and Azadirachta indica against house dust mites
Hanifah Laili Azima ; Awang Hazar Siti ; Ming Tze Ho ; Abidin Zainal Suhaili ; Omar Hashima Maizatul
Asian Pacific Journal of Tropical Biomedicine 2011;(5):365-369
Objective: To examine the acaricidal effects of the essential oil of Cymbopogon citratus leaf extract (lemongrass) and ethanolic Azadirachta indica leaf extract (neem) against house dust mites Dermatophagoides farinae (D. farinae) and Dermatophagoides pteronyssinus (D. pteronyssinus). Methods: Twenty-five adults mites were placed onto treated filter paper that is soaked with plant extract and been tested at different concentrations (50.00%, 25.00%, 12.50%, 6.25% and 3.13%) and exposure times (24hrs, 48hrs, 72hrs and 96 hrs). All treatments were replicated 7 times, and the experiment repeated once. The topical and contact activities of the two herbs were investigated.Results:Mortalities from lemongrass extract were higher than neem for both topical and contact activities. At 50 % concentration, both 24 hrs topical and contact exposures to lemongrass resulted in more than 91% mortalities for both species of mites. At the same concentration and exposure time, neem resulted in topical mortalities of 40.3% and 15.7% against D. pteronyssinus and D.farinae respectively; contact mortalities were 8.0% and 8.9% against the 2 mites, respectively. There was no difference in topical mortalities of D. pteronyssinus from exposure to concentrations of lemongrass and neem up to 12.50%; lemongrass was more effective than neem at the higher concentrations. Conclusions: Generally, topical mortalities of D. farinae due to lemongrass are higher than that due to neem. Contact mortalities of lemongrass are always higher that neem against both species of mites.
10.Effectiveness of pictorial health warning on cigarette packages: A cross-sectional study in Sarawak, Malaysia
Rahman MM ; Arif MT ; Abd Razak MF ; Suhaili MR ; Tambi Z ; Akoi C ; Gabriel Bain M ; Hussain H
Malaysian Family Physician 2015;10(3):19-26
Introduction: Specific health warning placed on the tobacco product packages is considered as an
effective and low-cost method for increasing the knowledge and awareness among the community.
Thus, a study was conducted to assess the perception of pictorial health warnings (PHWs) against
smoking among the adult rural population of Sarawak.
Methods: Cross-sectional data were collected from 10 villages in Kota Samarahan and Kuching
Division by face to face interview using modified Global Adult Tobacco Survey questionnaire. Nonprobability
sampling method was adopted to select the villages. All the households of the selected
villages were visited and an adult member was selected randomly from each house irrespective of the
sex. After missing value imputation, 1000 data were analysed using statistical software IBM SPSS
20.0 version.
Results: Analysis showed that 28.8% of the respondents were current smokers, 7.8% were past
smokers and the rest were non-smokers. Six items of pictorial health warnings were evaluated with
five point Likert’s scales for attractiveness, fearfulness and adequacy of the information. Analysis
revealed that the majority of the respondents had perceived awareness on PHWs, but the smokers
believed that this was not adequate to make them quit smoking. Only one-fifth (19.7%) of them
reported that current pictorial health warnings were sufficient to motivate people to quit smoking.
Conclusion: Though the PHWs on cigarette packages are appealing, it is not sufficient as a reason
to stop smoking. Thus, an approach using an integrated anti-tobacco public health programme
should be focused into the specific targeted community.