Fisher syndrome is characterized by ophthalmoplegia, ataxia and areflexia after preceding infection. The ophthalmoplegic symptom is described in a volume of Yomeibyo of the Shokan Ron, the classic Chinese encyclopedia of medical treatment. The Shokan Ron recommends Dai-joki-to as a treatment for this symptom. Accordingly, we administered Dai-joki-to to one patient diagnosed with atypical Fisher syndrome. The result was a prompt reduction of the ophthalmoplegic symptom in the patient. As Fisher syndrome is not a critical disease, Dai-joki-to administration should be considered as an alternative treatment to plasmapheresis.

To evaluate peripheral occlusive diseases quantitatively, we performed color duplex sonography. Between July 1996 and July 1998, we examined 68 limbs of 40 patients using color duplex sonography in addition to intraarterial digital subtraction angiography for evaluation of peripheral arterial occlusive disease. We classified the wave form of blood flow into four types (Type I-IV). Furthermore we measured the systolic velocities of the dorsal pedial and the posterior tibial arteries as well as the brachial artery. We also calculated the flow volume, and the ratio of systolic velocities and flow volume of lower to upper extremity (AVI, AFI). The waveform was significantly higher in Fontaine class III and IV, and showed remarkable improvement after arterial reconstruction. The value of AVI as well as AFI showed lower in Fontaine class I, II, III, and IV in order. In four limbs classified as Fontaine class II or more with normal ankle pressure index, the values of AVI were rather lower. On the other hand, three limbs with normal values of peak AVI (>0.9) and lower API (<0.75) were in Fontaine class I. The types of waveform correlated with clinical symptoms, and showed a remarkable regression after arterial reconstruction. The new AVI and AFI values had better correlation with clinical symptoms than API.

Over the past 10 months, we have performed mass screenings for thyroid diseases on the inhabitants of Aizu, Fukushima Prefecture, in cooperation with the women's department of the local agricultural cooperative. The number of examinees so far has reached a total of 2, 481 persons-2, 025 women and 456 men.
By palpation, goiter has been found in 208 (8.4%) persons-204 women and 4 men. The detection ratio was low when compared with the percentage recorded in Kamaishi, and higher than those in Kofu and Chiba.
Out of the 208 persons, 152 men and women underwent further examination, with the result that simple goiter was found in 35 persons; subacute thyroiditis in one person; chronic thyroiditis in 44; Basedow's disease in 8; and nodular goiter in 64.
Aizu stood highest next only to Kamaishi on the list in the chronic thyroiditis detection ratio. Kofu and Chiba followed in that order. As regards adenoma and adenomatous goiter in the thyroid grand, Aizu was on a par with Kamaishi, outdistancing Kofu and Chiba. Thyroid cancer was found less in Aizu than in Kamaishi and Kofu, but more or less at the same ratio with Chiba. As for Basedow's disease, Aizu ranked first.