1.Study clinical characteristics and the results with topical steroid in the treatment of ocular alkali burns
Journal of Medical Research 2008;58(5):39-45
Background: Alkali burns are severe injuries of the eyes. Recently, using topical steroid in treatment of ocular alkali burns has provided better outcomes. However, there is no study on treating ocular alkali burns by topical steroid in Vietnam. Objective: To describe the clinical characteristics and assess the outcome with topical steroid used in the treatment of ocular Alkali burns. Subject and Method: The author performed a prospective analysis of 45 alkali eye burns at the Trauma department of the National Institute of Ophalmology, Hanoi. All patients were treated with topical steroid and vitamin C. Results: There were 19 eyes were mild injures, 26 eyes were severe injuries. 32.5% had a good visual acuity. None of patients with severe injuries had a good visual acuity. Complications: corneal opacity: 42.2%, elevated IOP 17.8%. Conclusion: Treatment of ocular alkali burns with topical steroid and vitamin C is not associated with corneal perforating and provide a good outcome.
Alkali burn
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Steroid
2.Results of mitral valve reconstruction in Viet Duc hospital
Uoc Huu Nguyen ; Tien Anh Do ; Thanh Ngoc Le
Journal of Medical Research 2008;58(5):45-50
Background: Mitral valve diseases are the most frequent in the cardiac valvular acquired diseases. Valvuloplasty is a very good surgical treatment, also its techniques are difficult. Objective: (1) To describe features of valvular lesion and technique of valvuloplasty. (2) To evaluate the effects of these operations. Subject and Method: 95 cases of mitral valve reconstruction were studied and described retrospectively about pre- operative features, mitral valvuloplasty, and post-operative results. Results: Pre-operative cardiac failure >=2 nd level (NYHA) is 96.8%, with 100% of mitral valve insufficiency, 28.4% associated with valvular stenosis. Mean age of patient is 34.5 +/- 13.2. Each case must do an average 4/15 valvuloplasty techniques, the most frequent are: mitral valvular ring (67.4%), commissurotomy (57.9%), cordage section (45.3%)\u2026 Early post \u2013 operative result is very good: no mortality, mitral valvular function is improved significantly than pre-operative (p<0.001), no severe mitral stenosis or insufficiency. Long-term post operative control (3 months, 3 years, 5 years post \u2013 operation) present the stability of this valvuloplasty with high survival frequency (96.8% in 3 months, 96.2% in 3 years, 93.4% in 5 years), in the 78.5% ranges a good level, re-operation is only required in 3 cases with valvular replacement. Conclusions: Although the difficult technique of valvuloplasty \u2013 especially in rheumatic lesion, mitral valve reconstruction is a good and safe technique to treat the mitral valve diseases.
Alkali burn
;
Steroid
3.Study on the role of sex steroid hormones playing in the control of rat ovarian tumor growth.
Jin Gook CHOI ; Kyu Sub LEE ; Sang NA ; Yong Jin NA ; Won Whe KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):2645-2651
No abstract available.
Animals
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Gonadal Steroid Hormones*
;
Rats*
6.Effects of sex hormones on the induction of glutathione S-transferase-P positive hyperplastic hepatic nodules in rats.
Sang Jeon LEE ; Soo Tae KIM ; Sang Chul PARK ; Kye Yong SONG
Journal of the Korean Cancer Association 1991;23(4):708-722
No abstract available.
Animals
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Glutathione*
;
Gonadal Steroid Hormones*
;
Rats*
7.Steroid receptor profiles in human breast cancer and comparison of methodology for cytosolic procurement.
Jung Woon LEE ; Oh Hun KWON ; Kyung Soon SONG ; Kyung Ja RYU
Korean Journal of Clinical Pathology 1991;11(2):309-318
No abstract available.
Breast Neoplasms*
;
Breast*
;
Cytosol*
;
Humans*
;
Receptors, Steroid*
9.Effect of Occupational Lead on Male Sex Hormones.
Hyeong Su KIM ; Soung Hoon CHANG ; Won Jin LEE ; Jae Wook CHOI ; Jong Tae PARK ; Nam Won PAIK ; Rok Ho KIM
Korean Journal of Occupational and Environmental Medicine 2001;13(1):44-54
OBJECTIVES: This study was performed to evaluate the relationship between biological markers of lead exposure and level of sex hormones in men occupationally exposed to lead. METHODS: In this study, 33 male workers who employed at smelting and battery factories were compared with 33 male workers who were not exposed to lead. As biological markers of lead exposure, hemoglobin, ZPP, blood lead and urine lead were measured. As sex hormones, FSH, LH, testosterone, SHBG and FTI were determined. RESULTS: Hemoglobin level was significantly lower in exposed than in nonexposed group. Level of ZPP, blood lead, and urine lead were significantly higher in exposed than in nonexposed group. There was a trend that level of FSH, testosterone, SHBG, and FTI was lower in exposed than in nonexposed group respectively, but there were no statistical significance. In exposed group, FSH level was correlated with age, ZPP, and blood lead; testosterone level was correlated with hemoglobin, blood lead, urine lead, and SHBG; and FTI level was correlated with age. CONCLUSIONS: Level of some sex hormones were lower in exposed than in nonexposed group but there were no statistical significance between the exposed and the nonexposed group. But level of sex hormones were correlated with several biological markers of lead in exposed group. It suggests that occupational lead exposure might affect sex hormones.
Biological Markers
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Gonadal Steroid Hormones*
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Humans
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Male*
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Occupations
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Osmeriformes
;
Testosterone
10.Sex hormones among Workers Exposed to Pesticides.
Wonjin LEE ; Cheong Sik KIM ; Hyeong Su KIM ; Chang Hoon LEE ; Jin Seok KIM
Korean Journal of Occupational and Environmental Medicine 2000;12(2):179-186
OBJECTIVE: This study was carried out to determine the effects of occupational pesticides exposure on the level of serum Luteinizing Hormone(LH), Follicle Stimulating Hormone(FSH), testosterone in male workers. METHODS: Twenty-two male workers exposed to pesticides were compared with twenty-eight male workers at same factory who were not exposed to pesticides. The selected variables for studying reproductive hormones were LH, FSH and testosterone. As part of the baseline health status, subjects were asked medical history. RESULTS: There were no statistically significant differences on the level of LH, FSH, testosterone between the exposed and non-exposed group. Also the level of sex hormones were not significant difference with each department in exposed group. And the level of LH, FSH positively correlated with age. CONCLUSIONS: These results indicate that there are no alterations in LH, FSH, testosterone at workers exposed to pesticides. But our findings are highly preliminary because of a small sample size. Thus it calls for furthur investigation of the hormonal effects at workers exposed to pesticides.
Gonadal Steroid Hormones*
;
Humans
;
Lutein
;
Male
;
Pesticides*
;
Sample Size
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Testosterone