Objective To investigate the effect of Yishen Jianpi Yangxue Tongli fang (YSJP) on PCOS rats and approach the action mechanism of the recipe. Methods The animal model of levonorgestrel’s PCOS rat was established to observe the pregnancy rate and examinational results of light and electron-microscope. Results YSJP could promote pregnancy. The examinational results of light and electron-microscope showed that YSJP could recover the abnormal structure of organelle of the ovary. Conclusion YSJP had the effect of promoting pregnancy, recovering the injured organelle.