Objective:To investigate the effect of porcelain bake cycles on oxide layer form ed on cobalt-chromium alloy surface.Methods:Fixed spot analysis of EPMA methods was adopted to measure the oxygen at o mic percentage inward from the edge of cross-section interface of alloy pieces. The adherent state of oxide layer on the surface of substrate alloy was observed .Results:The oxide layer on the surface of alloy had stable thickness and contain ed more and more oxide as porcelain firing times increased.In some area,oxide la yer fractured from the substrate metal.Conclusion:Cobalt-chromium alloy frame should be abrased and polished thoroughl y after porcelain bake cycles.

Pterygium is a common ocular surface disorder,which causes lowing of vision even blindness once invading into cornea.The pathogenesis of pterygium is still incompletely clear.Recently studies showed that the interaction of a lot of factors lead to the proliferation of pterygium,and angiogenesis may play an important role in the formation and progression of pterygium.The therapies of pterygium focus on surgical resection with autologous conjunctival transplantation,amniontransplantation or transplantation of limbal stem cells,but a high recurrence rate of pterygium is worth studying.The angiogenesis of pterygium is a key problem.This article summarized the research outcomes in regulation and treatment about angionesis in pterygium.

Outcome of patients with adult acute lymphoblastic leukemia (ALL) is poor,and even worse among patients with relapsed/refractory ALL (R/R ALL).New treatments must be taken to overcome drugresistance to conventional chemotherapy for ALL.Humanized monoclonal antibody and chimeric antigen receptor gene modified T cells have become the focus of treatment in ALL.Lots of clinical trials in multiple research centers are in progress,and the results constantly upgrade which is effectively bring better curative effect and prognosis for R/R ALL patients.This is one of the hot topics at the 56th ASH annual meeting.

In recent years, various network assistant teaching platforms which have flooded into universities have been well received by the majority of teachers and students and educators. Network teach-ing platforms in oral medicine education now, especially the assistant teaching and information management have gradually risen to play a decisive role position. Combined with the characteristics of oral medical un-dergraduate course and the present situation of teaching, a preliminary practical use has been made on the new digital teaching management platform of College of Stomatology, Chongqing Medical University, and the analysis based on its advantages and disadvantages has also been made, in order to make an improvement of oral medicine teaching quality and management efficiency.

Objective To review the CT appearances and important differential diagnoses of various primary and secondary mesenteric neoplasms.Methods By describing the mesenteric anatiomy and major routes for the dissemination of metastatic mesenteric tumors, the article presents both the common and rare types of various primary and secondary mesenteric neoplasms, and addresses the characteristic CT appearances and important aspects of the differential diagnosis.Results CT study, especially the multi-slice spiral CT (MSCT), along with the clinical history and other related information, can nicely depict various mesenteric tumors and well differentiate them from infectious, inflammatory or vascular processes affecting the mesentery.Conclusion CT is the imaging method of choice for the evaluation of tumors of small bowel mesentery.

Objective To determine the early diagnostic value of serum C -reactive protein (CRP)、 total complement( CH50 ) activity and complement 3 (C3) concentration of premature women in the subclinical infection.MethodsSolid phase enzyme linked immunosorbent assay ( ELISA method ) was used for measurements of serum CRP levels. According to modified Mayer simple tubular colorimetric method and simple agar immunodiffusion method, we determined the CH50、C3 concentration respectively.Results Premature women with subclinical chorioamnionitis showed higher serum CRP concentration than that of normal pregnancy women (P<0.01). In the subclinical chorioamnionitis, the more serious the infection, the higher the CRP concentration, while CH50 and C3 concentrations were correspondently decreased. Serum CRP concentration in premature labor was the most sensitive index that suggested subclinical chorioamnionitis. ConclusionsSerum CRP、CH50 and C3 concentrations in premature labor are simple,reliable and accurate indexes for early diagnosis of subclinical infection.

Stem cell is one of the hot spot in the research area of biomedical engineering. Special attentions are drawn to the research and application of neural stem cells. Neural stem cells exist widely in central nervous system, which has the capacity of self-renewal and the potential to differentiate into other cells. The so-called engineered neural stem cell is constructed by using the technique of genetic engineering to make it be able to express various neural growth factors with high-performance and stability. The engineered neural stem cells have a great potential in the therapy of diseases of central nervous system, especially the spinal cord injury. This article reviews the research development of engineered neural stem cells, the problems confronted with it, and the trend for research in the future.

Objective To approach the role of Kupffer cell (KC) in regulation of liver regeneration after partial hepatectomy (PH). Methods Condition medium of kupffer cells (KCCM) was prepared and the role of KCCM in promoting rat primary hepatocytes proliferation was observed by MTT method. The PH animal model was reproduced in mice and the rate of liver regeneration was measured and the expression features of TNF-?, TGF-? and TGF-?_1 were determined by immunohistochemical methods after PH with KC depletion. Results KCCM could promote primary hepatocyte proliferation significantly (A=0.746?0.06) compared with control (A=0.536?0.06, P

Objective To explore the effect of preserving intercostobrachial nerve (ICBN) in axillary lymph node dissection on sensory disturbance for breast cancer.Methods Clinical data of 146 cases of stage Ⅰ,Ⅱ and Ⅲa breast cancer patients treated by modified radical mastectomy was analyzed.The patients were randomly divided into two groups.Retention group included 67 patients who were performed axillary lymph node dissection preserving ICBN,and 79 cases undergoing axillary lymph node dissection were taken as control group.Data of the two groups were assessed to compare the operation time,nunber of lymph nodes dissection and sensory abnormalities of upper arms.Results In the follow-up of 1,3 and 6 months,the incidence rate of the lateral upper ann sensory disturbance were 17.9％ and 74.9％,11.9％ and 60.7％,7.4％ and 59.5％ respectively in the retention and control group,and the difference was statistically significant (x2=46.78,P＜0.001;x2=36.54,P＜0.001;x2=42.80,P＜0.001).Meanwhile,there was no obvious difference between the retention and control group in operation time and number of lymph nodes(P＞0.05).No local recurrence after operation occurred in the follow-up of 8 months to 5 years.Conclusions For stage Ⅰ,Ⅱ and Ⅲ a breast cancer patients undergoing axillary lymph node dissection,retaining ICBN can significantly reduce the chance of the postoperative medial upper arm sensory disturbance,improve the quality of life with no increase of local recurrence rate.

Objective To construct and evaluate the effect of WeChat platform self-management program among colorectal cancer survivors with ostomies. Methods Totally 80 colorectal cancer survivors with ostomies were divided into two groups according the inclusive time with 40 cases each. The patients in the experimental group were applied WeChat platform self-management program, the control group were applied regular discharge telephone follow-up. The patients′ self-efficacy and quality of life were measured and compared prior to discharge, at 1 and 6 weeks after discharge. And the patients' occurrence of stoma complications were measured at 1 and 6 weeks after discharge. Results Due to quit research, finally complete the study of the experimental group for 36 cases, the control group for 35 cases. The total score of self-efficacy at 1 and 6 weeks after discharge were (72.05± 9.68), (84.91±16.01) points in the experimental group, and (63.00 ± 13.26), (72.20 ± 15.61) points in the control group, and there were statistically significant differences (t=-2.586, 3.388, P<0.01). The total score of quality of life at 1 and 6 weeks after discharge were (43.68±8.32), (49.49±8.61) points in the experimental group, and were (37.09± 5.57), (40.42 ± 8.01) points in the control group, and there were statistically significant differences (t=3.926, 4.596, P<0.05). Repeated measures analysis of variance showed that the intervention effect on the overall self-efficacy, stoma care self-efficacy, social self-efficacy and stoma quality of life was significant (F=4.287-10.744, P<0.05);the time effect on the overall self-efficacy and quality of life was significant (F=146.109, 90.105, P < 0.05); there were interactions between the effect of WeChat platform self-management program and time on the overall self-efficacy, stoma care self-efficacy, social self-efficacy, dietary efficacy, sexual life satisfaction efficacy, keep active efficacy and stoma quality of life ( F=4.452-21.777, P<0.05) . Chi-square analysis showed that the patients′occurrence of stoma complications at 1 and 6 weeks after discharge in the experimental group were lower than those in the control group:8.33%(3/36), 5.56%(2/36) and 31.43%(11/35), 25.71%(9/35), the differences were significant (χ2=5.980, 5.508, P < 0.05). Conclusions WeChat platform self-management program may be helpful for colorectal cancer survivors with ostomies after discharge in improving self-efficacy and quality of life, and in reducing stoma complications incidence.