Chinese genuine regional herbs are a combination of nature resource and traditional knowledge. Although we can make it to be an intellectual property product through applying geographical indication or certification mark, the value realization of Chinese genuine regional herbs should be supported by the merchant capital. Meanwhile, the merchant capital also disturbs the reasonable market price of Chinese genuine regional herbs. We should combine the merchant capital with Chinese genuine regional herbs, apply permission for sale and set up a new professional cooperation mode to maintain the market credibility and reasonable price of Chinese genuine regional herbs.

Postprandial hyperglycemia is one of the characteristics of glucose profiles in Chinese T2DM patients. High-ratio premix insulin analogues with advantages of excellent pharmacokinetic characteristics and flexible and convenient administration provide a comprehensive solution for Chinese T2DM patients to effectively control postprandial glucose and reduce blood glucose fluctuation. This paper is a literature review on its clinical evidence and experience.

Atopic dermatitis is a common chronic recurrent atopic constitution-associated inflammatory skin disease mainly characterized by eczematous lesions and itching. Its etiology and pathogenesis are still not very clear, and there are many controversies about its origin, definition, clinical phenotypes and diagnostic criteria. This review analyzes and discusses these controversies in order to provide a meaningful reference for the diagnosis and treatment of atopic dermatitis.

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Resuscitation*

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Animals ; Embryo Implantation* ; Embryonic Structures* ; Female ; Mice* ; Pregnancy

Child ; Genetic Diseases, Inborn ; genetics ; Humans

objective To analyze the clinical treatment effect and evaluate the value of the intervention measures by giving nursing intervention to patients with upper digestive tract bleeding caused by hepatocirrhosis. Methods The research object were 100 patients with liver ciirhosis complicated with upper digestive tract bleeding caused by hepatocirrhosis from June 2009 to June 2011.They were randomly divided into the observation group and the control group with 50 patients in each group.The control group was given routine nursing measuress,including admission instruction and health education,based on this,the observation group was given nursing intervention measures,its main measuress including; psychological counseling intervention,behavioral therapy intervention and other comprehensive intervention methods.The nursing effect and incidenee of complications were analyzed between two groups of patients. Results The total effective rate was 98％ in the observation group,higher than 80％ of the control group.The incidence rates of recurrent hemorrhage.,mortality,constipation,hepatic encephalopathy of the observation group was significantly lower than those of the control group. Conclusions Patients with upper digestive tract bleeding caused by hepatecirrhosis showed various clinical symptoms due to many reasons.Nursing intervention can effectively alleviate the clinical symptoms of patients improve the treatment effects,and help them recover soon.It is worthy of clinical popularization and application.

Objective To investigate the effect of comprehensive nursing intervention on lung function and depressive mood of patients with chronic obstructive pulmonary disease and depression,and summarize the effective care of the disease,in order to achieve better efficacy in clinical care and treatment in the future.Methods 58 cases of patients with chronic obstructive pulmonary disease and depression in our hospital were chosen as the research object.They were randomly divided into the routine care group and the integrated care intervention group with 29 patients in each group.The routine care group received conventional care,and the integrated care intervention group was given comprehensive care according to the patients'individualized condition and psychological intervention on the basis of conventional care.The patients' lung function and severity of depression 6 months and 12 months after treatment were compared.Results In the integrated care intervention group,the lung function 6 months and 12 months after treatment were significantlybetter than the routine care group,the degree of depression was significantly slighter than routine care group.The effective rote of treatment was higher than the routine care group.Conclusions The efficacy of integrated care intervention for patients with chronic obstructive pulmonary disease and depression was significant,it can improve the lung function and depression state of patients,which is worthy of clinical application.

Objective To investigate the effect of Poly (ADP-ribose) polymerase(PARP) in heart ischemia/reperfusion (I/R) injury in rats.Methods Forty - eight rats were divided into 4 groups randomly.3,4 -dihydro-5- [ 4- ( 1 -piperidinyl) butoxy ] - 1 ( 2H ) - isoquinolinone ( DPQ ),an inhibitor of PARP,was used to inhibit the expression of PARP in rat's heart.The expression of PARP,heart infarct size,heart function,and apoptosis of the cardiomyocytes were detected of different groups of the rats.Results The expression of PARP increased in rat heart I/R injury.Mter DPQ was used,the expression of PARP decreased significantly(5.04 ± 1.25 vs 2.33 ± 0.65,t =1.35,P ＜ 0.05 ) ; inhibition of the expression of PARP improved the cardiac function; inhibition of the expression of PARP decreased cells apoptosis from (34 ± 6.2) ％ to (323 ± 3.8) ％ ( t =2.25,P ＜ 0.05).Conclusions The expression of PARP increased in rat heart I/R injury.Inhibition of the expression of PARP could protect the heart from I/R injury.

ObjectiveTo investigate the effects on QT dispersion in patients who received maintenance hemodialysis by dialysate with different concentration of potassium. MethodsTook 57 patients who received maintenance hemodialysis as dialysis group, took another 30 healthy subjects as control group, patients in dialysis group alternatively received hemodialysis by dialysate with potassium concentration of 2.0mmol/L and 3.0mmol/L once. QT interval of both groups were recorded by 12-lead synchronized ECG and then QT dispersion and QTcd were calculated. ResultsQTd and QTcd of dialysis group were(52.7 ±8.2) and(63.2 ±9.0)ms respectively and which were significantly higher than control group, the difference between groups was statistically significant( t =2. 638,2. 750, both P ＜ 0.05 ) ; QTd, QTcd and the incidence of arrhythmia of 2.0mmol/L K + group were ( 63.5 ± 7.6), ( 72.3 ± 8.0)ms and 22.8％ ( 13/57)respectively and which were all significantly higher than 3.0mmol/L K + group,the differences between groups were statistically significant ( t =2. 245,2.351, x2 =5. 599, all P ＜ 0.05 ). ConclusionQT dispersion reflectsed the heterogeneity of ventricular repolarization and electrical instability,and the use of dialysate with potassium concentration of 3.0mmol/L could shorten QT interval and reduce the incidence of arthythmia.