1.THE STUDY OF FEMALE INFERTILITY WITH ANTI-TPO AND ANTI-TG AUTOIMMUNE DEFICIENCY IN THYROID GLAND
Tuvshibayar N ; Solongo M ; Ariunaa E ; Davaakhuu S ; Khishigjargal U ; Dulguun Kh ; Munkhzol M ; Odkhuu E
Innovation 2018;12(1):35-39
BACKGROUND: According to the World Health Organization (WHO), 10-15% of couples of reproductive age have infertility. According to researcher D. Sukhe (1999), hormonal infertility in the reproductive age of women was 33.6%, which was a large part of the cause of infertility. In recent years, the number of cases of endocrine disorders, including malignancy and sexually transmitted infections, has been increasing year by year. According to WHO reports, thyroid disorders have a prevalence of 49.3% for active reproductive age (30-50). According to the report of the Health Development Center in 2016, since the thyroid disorders are the second most common disease in endocrine gland disease, our study found that the infertility in reproductive age of women can be substantial due to the loss of thyroid gland.
METHODS: The study was carried out by the couple of 20-45 year-olds and modeled as an analytical study model. The questionnaire was used for the couple’s interviews and some of the measurement of body and serum use of TOSOH Corporation AIA-360, Tokyo, Japan. On the serum, anti-TPO and аnti-TG carbohydrates are identified by the Cobas e-411 analyzer under the manufacturer’s accompanying protocol.
RESULTS: 76.7% of women were diagnosed with infertility euthyroid, 0.7% hyperthyroidism, 22.6% hypothyroidism (3.8% with overt hypothyroidism and 18.8% subclinical hypothyroidism). Prevalence of TAI, in 6.7% isolated positive anti-Tg were found, and 14.3% had isolated positive TPO, In 3.7% of cases, both types of autoantibodies were present.
We analysed binary logistic regression for anti-TPO and anti-TG autoantibody in the positive and negative group in past obstetrics history, evidence of positive of anti-TPO and anti-Tg was increased risk of miscarriage 2.2 times (OR = 2.2, p <0.01).
CONCLUSIONS: Women with disorders in our study have high percentage of subclinical hypothyroidism and have higher rate of thyroid autobodies in serum which may be a problem for women with infertility and pregnancy complications due to the loss of thyroid gland. There is a need to develop a principle of recovery and treatment.
2.Comparative study of pharmacists in Mongolia and Korea
Solongo B ; Bayarbakhdal Ch ; Margad M ; Soyol-Erdene Ts ; Baigalmaa D
Mongolian Pharmacy and Pharmacology 2018;13(2):27-31
Introduction:
Now days in case of two countries’ cooperation has been developing day by
day, diversified activities such as collaboration and exchanging experience has been performing in
health sector, medical science, besides pharmacology.
Methods:
This study aimed to compare two countries’ pharmacist’s acquirements and roles
and provide information to Mongolian Pharmaceutical Universities and pharmacist students.
Pharmaceutical: Statistics :
Population:
- 3 million in Mongolia
- 5 million in Korea
Number of pharmacists:
- 1726 (by 2016) in Mongolia
- 33182 (by 2016) in Korea
Number of Pharmaceutical Universities
- 7 universities, including 1 public and 6 private in Mongolia
- 34 universities, including 10 public and 25 private in Korea
Results
As a result of this study, pharmacist’s acquirements, role and working sectors of pharmacists
in two countries are ordinarily same. There are some different sides below:
• Period of pharmacist’s preparatory training is 5 years at university in Mongolia and 2+4 years in Korea.
• Pharmaceutical Universities of Mongolia trains 2 specialists: pharmacist (bachelor`s degree) and pharmacist (diplom`s degree); College of Pharmacy of Korea trains pharmacist, pharmacist of traditional medicine and pharmaceutical engineering.
• For a role of business, in Mongolia pharmacist (diplom`s degree) is a separate specialist trained with diploma, whereas in Korea, if pharmacist gets a license, they have a right to compound a medicine legally, but commonly in pharmaceutical industry.
• As for sector, pharmacists are trained in many specializes, such as general pharmacist, clinical
pharmacist, military pharmacist, nuclear pharmacist, cancer pharmacist and vet pharmacist.
• Special legal professional pharmacists work in Korea, such as governmental organization’s pharmacist, civil service pharmacist and public organization’s pharmacist.
• No person, other than pharmacists or oriental pharmacists may dispense drugs, and pharmacists or oriental pharmacists shall dispense drugs within the limit of the license, respectively: However, students who major in pharmacy at college may dispense drugs within the limits prescribed by Ordinance of the Ministry of Health and Welfare.
3.Study of chloroformic fraction of bassia dasyphylla (fisch. Et mey.) Ktze. By gas chromatography mass spectrometric method
Solongo T ; Gerelt-Od Ya ; Dumaa M ; Batsuren D ; Tunsag J
Mongolian Pharmacy and Pharmacology 2020;17(2):43-48
Abstract
Chloroformic fraction from the aerial parts of Bassia dasyphylla (fisch. et mey.) ktze. growing in Mongolia have been studied by means of Gas Chromatography Mass spectrometry method. Benzyl alcohol, phenol 2-methoxy, 2-methoxy-4-vinylphenol, 2-propenoicacid, 3- (2-hydroxyphenol)-,(E), Ibuprofen methyl ester, 3’,5’-dimethoxyacetophenone, 3-hydroxy-β-damascone, megastigmatrienone, 5-hydroxy-7-methoxy-2-(p-methoxyphenyl) -6,8-dimethyl-4-chromanon 18 compounds were determined and found for the first time from this plant species.