1.MICROSURGICAL ANATOMY OF THE ANTERIOR INFERIOR CEREBELLAR ARTERY
Sizhe FENG ; Xuezhong WEI ; Zaihu XU
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
The anatomy of the trunks and branches of anterior inferior cerebellar artery(AICA) was studied and its surgical importance especially in the operation for acoustic neuroma(AN), was discussed.15 fresh adult cadavers were perfused with ABS via internal carotid artery and vertebral artery and then dissected under operation microscope in detail. AICA was constantly present in all specimens. The incidence of labyrinthine artery(LA), recurrent perforating artery(RPA), subarcuate artery(SA),and cerebellar subarcuate artery (Cer.SA) was 100%,86.7%,80% and 16.7%, respectively. 97.1% of LA entering the internal auditory meatus (IAM) were located under the facial vestibulocochlear nerve complex, 56.7% of RPA passed between it ,and 75% of SA was located posteroinferiorly to it .60.7% of the loop of AICA was situated close to the IAM, and 53.6% of them lay between the Ⅶ and Ⅷ cranial nerves. These data may be helpful in microneurosurgical operation and radiography.
2.Relationship between blood pressure and body mass index,waist-to-height ratio and body surface area among 7-to-13 year old children in Jinpan district,Haikou city
Wenjuan HUANG ; Cheng WANG ; Sizhe XU
Chinese Pediatric Emergency Medicine 2016;23(3):190-194
Objective To survye the relationshi p between blood pressure and body mass index ( BMI) ,waist-to-height ratio( WHtR) and body surface area( BSA) amogn 7 to 13 years old children in Jin-pan id strict,Haikou city.Methods A total of 1 018 school-age children aged from 7 to 13 years old were se-lected from two elementary schools in Jinpan distir ct,Haikou cti y.Blo odp ressure,height, weight and wa ist circumferencew ere measuredi n all children.BMI,WHtR,BSA were calculated and statistci al analyis s was performed by SPSS 22.0 software.Results The Pearson Correlation Coefficient of BMI and bloodp er ssure showed that BMI was posti vely correlatde with ob th systolic and id astoil c blood pressure(r=0.489,0.454, P<0.01,respective ly).The Pearos n Correlation Cofe ficient of WHtR and blood pressure showed that WHtR was positively correlated with both systolic and diastolic blood pressure(r=0.294,0.310,P<0.01,respec-tively) .The Pearson Correlation Coefficient of BSA and blood pressure showed that BSA was positively cor-related with both systolic and diastolic blood per ssure(r=0.603,0.520,P<0.01,respectively).The WHtR adn BSA of hypetr ension group were higher than those of the non-hypertension group( P<0.01) in both male and female children.Conclusion The blood pressure in 7 to 13 years old school-age children of Jinpan dis-trict,Haikou city is related to the BMI,WHtR and BSA respectively.
3.Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak in Shanghai.
Ziyu FU ; Dongguo LIANG ; Wei ZHANG ; Dongling SHI ; Yuhua MA ; Dong WEI ; Junxiang XI ; Sizhe YANG ; Xiaoguang XU ; Di TIAN ; Zhaoqing ZHU ; Mingquan GUO ; Lu JIANG ; Shuting YU ; Shuai WANG ; Fangyin JIANG ; Yun LING ; Shengyue WANG ; Saijuan CHEN ; Feng LIU ; Yun TAN ; Xiaohong FAN
Frontiers of Medicine 2023;17(3):562-575
The Omicron family of SARS-CoV-2 variants are currently driving the COVID-19 pandemic. Here we analyzed the clinical laboratory test results of 9911 Omicron BA.2.2 sublineages-infected symptomatic patients without earlier infection histories during a SARS-CoV-2 outbreak in Shanghai in spring 2022. Compared to an earlier patient cohort infected by SARS-CoV-2 prototype strains in 2020, BA.2.2 infection led to distinct fluctuations of pathophysiological markers in the peripheral blood. In particular, severe/critical cases of COVID-19 post BA.2.2 infection were associated with less pro-inflammatory macrophage activation and stronger interferon alpha response in the bronchoalveolar microenvironment. Importantly, the abnormal biomarkers were significantly subdued in individuals who had been immunized by 2 or 3 doses of SARS-CoV-2 prototype-inactivated vaccines, supporting the estimation of an overall 96.02% of protection rate against severe/critical disease in the 4854 cases in our BA.2.2 patient cohort with traceable vaccination records. Furthermore, even though age was a critical risk factor of the severity of COVID-19 post BA.2.2 infection, vaccination-elicited protection against severe/critical COVID-19 reached 90.15% in patients aged ≽ 60 years old. Together, our study delineates the pathophysiological features of Omicron BA.2.2 sublineages and demonstrates significant protection conferred by prior prototype-based inactivated vaccines.
Humans
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Aged
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Middle Aged
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COVID-19/prevention & control*
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SARS-CoV-2
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Pandemics/prevention & control*
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China/epidemiology*
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Disease Outbreaks/prevention & control*
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Vaccination