Objective To investigate the risk rate of infection with SARS coronavirus in health care workers in an designated hospital, and to assess the effectiveness of the isolation system in prevention of nosocomial transmission of SARS. Methods Questionnaire was submitted to all health care workers related with SARS patients, and ELISA assay was performed to detect IgG antibody against SARS coronavirus for all of them. Results 450 health care workers were submitted the same questionnaire, 445 questionnaires were returned, and 441 blood samples were collected. It was confirmed that all health care workers involved had complied with the isolation guidelines as formulated by the authority of the hospital. Two hundred and sixty persons out of 441 were classified into the group who had close contact with SARS patients and/or SARS materials. Among these 260 workers, IgG antibody against SARS Coronavirus was detected in 5 of them, who had either worked in the SARS ward, CCU (where 3 SARS probable cases had stayed for a short term), paediatric ward, center for sample transference, or laundry. Therefore, there was no statistically significant difference in the risk rate between the group of workers who had close contact with SARS patients and/or SARS materials and the group without contact. Conclusion The current isolation system against SARS was effective, though might not perfect.

Objective To analyze the status quo and influencing factors of patient safety culture among medical staffs in the hospitals of Shenzhen City to provided reference for its improvement and conduct the patient safety culture research by other medical institutions.Methods The Patient Safety Culture Questionnaire of Medical Institutions(PSCHO) was adopted to investigate on 1000 medical persons from February to May 2016.Results The total score of patient safety culture in medical staffs was (3.53±0.40) and,the difference among different categories of medical persons had no statistical significance (P＞ 0.05).The differences among the medical staffs with different working ages,communication frequency with patients,training times,concern frequency had statistical difference(P＜0.05).Conclusion The patient safety culture level in Shenzhen City is higher.However,the sense of blame and shame is one of the important factors impeding the promotion of the patient safety culture in hospitnl.Hospital should conduct the targeted improvement to the related factors affecting the patient safety culture from the aspects of organism,department and individual level.