1.Six Cases with \lqHonton\rq Disease Successfully Treated with Combination of Goshuyuto Extract and Ryokeijutsukanto Extract
Yuji KASAHARA ; Yutaka KOBAYASHI ; Atsushi CHINO ; Nobuyasu SEKIYA ; Takao NAMIKI ; Kenji OHNO ; Masaki RAIMURA ; Sumire HASHIMOTO ; Keiko OGAWA ; Hirokuni OKUMI ; Yumiko KIMATA ; Yoshiro HIRASAKI ; Toshiaki KITA ; Katsutoshi TERASAWA
Kampo Medicine 2009;60(5):519-525
We report six cases with honton disease successfully treated with a combination of goshuyuto extract and ryokeijutsukanto extract. Five of the cases were diagnosed as panic disorder, and the remaining case as generalized anxiety disorder. All six cases complained of palpitation, nausea, dizziness, headache and anxiety attacks. We diagnosed them as a hontonto (Zhouhou fang) indication. Their various complaints disappeared after combination therapy with those extracts. Furthermore, efficacy of the combination therapy was proven to be equal to hontonto. These cases suggest that the combination therapy with goshuyuto extract and ryokeijutsukanto extract is useful in place of hontonto.
Combined Modality Therapy
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2.Prevalence of smoking and drinking habits among Form Six students in Petaling District, Selangor.
M Z Nor Afiah ; A R Hejar ; K C M Kulanthayan ; J Fadhilah ; T H Law
The Medical journal of Malaysia 2006;61(1):41-7
Smoking and alcohol intake patterns may persist from adolescence to adulthood. The aims of this study are to determine the prevalence and factors associated with smoking and drinking habits among Form Six students. This was a cross-sectional study conducted in January 2003 among Form Six students from government schools in the Petaling District, Selangor. A hundred and thirty six self-administered questionnaires were distributed to students selected through multistage stratified sampling. Response rate in this study was 90.1% (136/151). The respondents were mainly Chinese 60 (44.1%) and female 88 (64.7%). The prevalence of smoking was 22.8%, whereas the prevalence of alcohol intake was 47.8%. Only 33.1% of the respondents practiced undetermined activities and 1.5% have undetermined characters. There were significant associations between smoking and males (Adjusted OR 2.56, 95% CI 1.02-6.43) and smoking and alcohol intake (Adjusted OR 2.74, 95% CI 1.11-6.78). Alcohol intake has significant negative association with Malays (Adjusted OR 0.83, 95% CI 0.03-0.27). Smoking habits among adolescents were associated with males and alcohol intake. However, only alcohol intake was negatively associated with Malays. Program interventions to reduce behavioral problems, particularly smoking and alcohol intake should be emphasized.
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3.Evaluation of the effectiveness of Lean Six Sigma Approach for SARS-CoV-2 RT-PCR Turnaround Time (TAT) improvement at a hospital-based tertiary laboratory.
Dian Lagamayo ; Rose Lou Marie Agbay ; Sarah Jane Datay-Lim
Philippine Journal of Pathology 2023;8(1):27-31
OBJECTIVES:
This study aims to evaluate the effectiveness of the Lean Six Sigma approach in improving
procedure for (TAT) of reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-CoV-2 testing at
The Medical City. Specific objectives of the study are to determine the following: 1) baseline sigma and
average TAT (in hours); 2) post-implementation sigma and average TAT (in hours) 3) compare if there is a
significant improvement between baseline and post-implementation sigma and average TAT (in hours)
4) effect on workflow efficiency.
METHODOLOGY:
Lean Six Sigma method for quality improvement was applied using DMAIC: Define, Measure,
Improve, and Control. The root causes identified were lack of manpower, equipment, space, and manual
and complex processes. Then, process wastes were identified, and corresponding proposed solutions
were sustained in the control phase, such as standardization and the use of automation. Measurement of
turn-around time and six sigma of the process were performed for evaluation.
RESULTS:
Results showed a significant improvement in the TAT in RT-PCR results, with most results released
within 24 hours. The pre-Lean Six Sigma data on TAT were as ollows: 24.88% released within 24 hours; 65.14%
released within 24-48 hours; 3.56% released within 48-72 hours, and 6.42% released in more than 72 hours.
The post Lean Six Sigma TAT were as ollows: 95.32% released within 24 hours; 4.29% released within 24 to
48 hours; 0.13% released within 48-72 hours, and 0.12% released more than 72 hours. The computed sigma
post-implementation was increased from 3.56 to 4.82. The p-value was calculated using the chi-square test,
and the computed chi-square statistic is 1894.1021. The p-value is <0.00001 and the result is significant at
p<.05. Although there is a significant decrease in the volume of samples post implementation due to the
changing COVID-19 situation, real time TAT was improved. It also resulted to increased workflow efficiency
with the use of lesser manpower with more appropriate utilization.
CONCLUSION
Applying the Lean Six Sigma method to improve quality processes in the laboratory is shown
to be practical, cost-effective, and straightforward.
Lean Six Sigma
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SARS-CoV-2