1.Observations on Therapeutic Effect of Back-Shu Acupoint in Treatment of Asthma
Journal of Acupuncture and Tuina Science 2008;6(1):32-35
Objective: To investigate the therapeutic effect of Back-Shu acupoint in treating asthma. Methods: Sixty-one patients were randomly divided into a Back-Shu acupoint group, a acupuncture-moxibustion group and a acupuncture group. All the three groups were treated twice a week, 10 times made up a treatment course. The therapeutic effect was evaluated after three courses of treatment. Results and conclusion: The control and marked effective rate were significantly higher in the Back-Shu acupoint group and acupuncture-moxibustion groups than in the acupuncture group (P<0.05). They were slightly higher in the acupuncture-moxibustion group than in the Back-Shu acupoint group, but there was no statistically significant difference. The results indicated that the Back-Shu acupoints have a good therapeutic effect in treating asthma.
2.Clinical efficacy of atorvastatin in patients with lacunar infarctions and influence on cerebrovascular reactivity
Chinese Journal of Primary Medicine and Pharmacy 2010;17(18):2462-2463
Objective To investigate the clinical efficacy of atorvastatin in patients with lacunar infarctions (LI) and influence on cerebrovascular reactivity(CVR). Methods 60 patients with LI were randomly divided into observation group and control group. The patients of control group were given aspirin treatment, patients of observation group were given atorvastatin combination with aspirin therapy. The breath-holding index(BHI) before and after treatment was calculated. After continuous treatment for 3 months the clinical efficacy was evaluated. Results The total effective rate of the observation group was 90. 0% ,it was significantly higher than that of the control group(73.3% ),compared with the control group the difference was significant( x2 = 10. 428 ,P < 0. 05). The bilateral BHI of observation group significantly increased, compared with per-treatment and control group the difference was significant ( t =9. 455,6. 135 ,all P < 0. 05 ) ,but the bilateral BHI of control group had no significant difference compared with pertreatment ( P > 0. 05 ). Conclusion Atorvastatin could effectively improve CVR in patients with LI. Therefore, atorvastatin had great significance for the prevention of stroke.
4.A evaluation research for the optimization and utilization of medical equipment in pediatric hospital
China Medical Equipment 2017;14(2):110-111,112
Objective:To provide more details and guide the management and usage as well as purchasing for medical equipment, so as to realize the optimization and utilization of the medical resources and impel Precision Medicine Initiative.Methods:The cost-effective analysis and the rate of return analysis of two large-scale precision equipments (MRI and Fundus camera usage) during January 2015 and June 2016 were performed. Besides, the equipment cost was divides into several more detailed projects in the research.Results: The rate of return of MRI in the first half year of 2016 was 8.5%, which was obviously higher than the one of 2015 which was 4.1%; the rate of return of Fundus camera usage in the first half year of 2016 was 25.9%, which was also obviously higher than the one of 2015 that was 15.0%. In the analysis, the depreciation of equipment was the main cost.Conclusion: It was critical and necessary to strengthen the standardized operation and routine maintenance in operation, in order to improve their safety usage rate.
5.Accuracy of monitoring neuromuscular blockade by transcutaneous electrical stimulation at P6 acupuncture point
Siwei DONG ; Yanlin WANG ; Chengyao WANG
Chinese Journal of Anesthesiology 2009;29(7):639-641
Objective To evaluate the accuracy of monitoring the neuremuscular blockade intraoporatively by transcutaneous electrical stimulation at the P6 acupuncture point. Methods Thirty-five patients, ASA Ⅰ - Ⅲ, BMI≤35 kg/m2 scheduled for abdominal surgery were selected. Anesthesia was induced by sufentunil 0.2-0.3 μg/ kg iv, propofol 2,5-3.5 mg/kg iv. Neuromuscular monitoring was performed by TOF Watch SXR at the P6 acupuncture point on the left forearm and ulnar nerve on the right. The current intensity and gain were recorded frem all the patients;onset time, recovery time of TOF ratio 25% and TOF ratio 90% of atrucurium were also obtained by TOF stimulation on the P6 acupuncture point and the ulnar nerve in patients who were administered a single bolus of atracurium 0.5 mg/kg iv during operation. Controlled ventilation commenced after endotracheal intubation. Results There were no significant differences between the P6 acupuncture point and the ulnar nerve in stimulus intensity or gain ( P > 0.05 ). There were no significant differences between the P6 acupuncture point and the ulnar nerve in onset time, recovery time of TOF ratio 25% and TOF ratio 90% (P > 0.05).Conclusion Transcutaneous electrical stimulation at the P6 acupuncture point can be used to monitor neuromuscular blockade intraoperafively.
6.CT Differential Diagnosis of Salivary Lesions
Youzhi ZHU ; Siwei WANG ; Wenbin LIAO
Journal of Practical Radiology 2001;0(05):-
Objective To study CT diagnostic value of benign and malignant salivary gland lesions.Methods CT features in 36 cases with pathologically-proved salivary lesions were retrospectively analyzed.There were 19 cases with benign tumors,5 cases with chronic inflammation,1 case with tuberculosis and 11 cases with malignant tumors.Results Benign tumors were regular in 17 and well-defined in 16.All cases with chronic inflammation and 1 case with tuberculosis were regular but ill-defined.Benign lesions showed homogeneous or inhomogeneous density.Of all 11 malignant tumors,7 cases presented ill-defined margin with irregularity in shape,infiltration of adjacent subcutaneous fat tissue and disappearing of epiderm.Salivary glands enlarged and looked like "cast form" in malignant tumors.Most of the malignant tumors and benign tumors presented inhomogeneous density.Conclusion CT scan is of important value in the diagnosis of salivary diseases.
7.Diagnosis and treatment of nodular goiter with thyroid carcinoma
Gewen ZHANG ; Siwei ZHU ; Zhiming WANG
Chinese Journal of General Surgery 1994;0(05):-
Objective To investigate the diagnosis and treatment of nodular goiter with thyroid carcinoma.Methods The clinical data of forty cases of nodular goiter with thyroid carcinoma admitted to our hospital from January 2005 to December 2007 were retrospectively analyzed.Results Among the 40 cases,only four cases were preoperatively diagnosed as nodular goiter with thyroid carcinoma.All cases received operation and the diagnosis were comfirmed by frozen section examination.Various modes of thyroidectomy were performed according to the pathological results,including four cases had unilateral total thyroidectomy,27 had unilateral total thyroidectomy combined with opposite subtotal thyroidectomy,one case had bilateral subtotal thyroidectomy,and eight cases of bilateral total thyroidectomy.Of all 40 cases,11 cases received unilateral cervical lymph node dissection.There were only three cases occurred convulsion or numbness,and no hoarseness occurred postoperatively.Compared to simple nodular goiter,the incidence of calcification in nodular goiter with thyroid carcinoma was significantly increased(P
8.Analysis on Application of Intelligent Monitoring System for Dosage and Frequency of Drugs in the Monitoring of Non-antimicrobials
Xiaobo ZHAI ; Zhigao HE ; Siwei BAO
China Pharmacy 2005;0(21):-
OBJECTIVE: To promote rational use of non-antimicrobials based on Intelligent Monitoring System for Dosage and Frequency of Drugs.METHODS: Base on the information system of hospital,dosage and frequency of drugs were collected from Intelligent Monitoring System for Dosage and Frequency of Drugs and connected with patients’ ages,weights,body surface areas and renal functions.1 315 hospitalized prescriptions of non-antimicrobials were randomly collected from our hospital one day.RESULTS: There were 200 warnings of overdosage each time and moderate frequency,91 warnings of overdosage each time and inadequate frequency,43 warnings of moderate dosage each time and inadequate frequency,41 warnings of moderate dosage each time and excessive frequency,15 warnings of inadequate dosage each time and moderate or inadequate frequency for drugs that needn’t be adjusted according to age and renal functions.There were 11 warnings of overdosage and excessive frequency for drugs that should be adjusted according to patients’ age and renal function.CONCLUSION: This kind of connection is practical,when prescriptions of non-antimicrobials which violate the rules of dose and (or) frequency are identified by system.But the significance of Intelligent Monitoring System for Dosage and Frequency of Drugs should be proved by practice.
9.Studies on the pharmacokinetics of the intravesical instillation of mucous adhesive anticancer agent hydroxypropylcellulose-mitomycin C
Siwei ZHOU ; Guofang ZHAO ; Xiaodong SONG
Chinese Journal of Urology 2000;0(12):-
Objective To study the drug retention of HPC MMC in bladder after intravesical instillation. Methods The pharmacokinetics of the intravesical mucous adhesive anticancer agent HPC MMC in urine and in tissue were comparatively studied with conventional mitomycin C aqueous solution(S MMC) by means of animal experiment. Results After instillation, the half life of MMC in urine in the 2 groups was 2.61 h and 0.56 h and in tissue 2.33h and 0.46 h respectively. Conclusions Suggesting that HPC MMC remained longer within the urinary bladder. It may be therapeutically more efficient.
10.cAMP induces axonal regeneration in spinal cord injury of rats
Xiangrong CHEN ; Hui JIANG ; Siwei YOU
Chinese Journal of Orthopaedics 2001;0(05):-
Objective cAMP promotes neurite outgrowth in vitro. The study is aimed to understand whether cAMP can repair spinal cord injury of rats. Methods 56 rats models of spinal cord hemisection were adopted and randomly distributed into six groups. Dibutyryl-cAMP or physiological saline was injected either once in the motor cortex with an amount of 6 ml of 50 mmol/L cAMP, or continuously infused through a polyethylene tube connecting with a micro-pump in the spinal lesion area or in the subarachnoid space with a total amount of 72 ml of 10 mmol/L cAMP for 72 h. The distribution of neurofilament (NF) in the lesion area was observed by immunohistochemistry. Corticospinal tracts (CST) and spinal axons regeneration were investigated by CST and spinal axons anterograde tracing with biotinylated dextran amine (BDA). The function of hindlimb movements were evaluated by BBB scales and as a reference to assess the repairing effect of treating strategy. Results NF were densely distributed and extended in the lesion area in the cAMP groups, but no connection could be found with the NF in the caudal. No axonal regeneration could be achieved when cAMP was input into the subarachnoid space. Many regenerated axons, including some CST axonal regeneration were presented in the lesion areas in cAMP groups though no continuous long regenerated axons traversed the lesion area, while there was no regenerated axon in the lesion areas in the control groups. All the rats restored to normally walk 4 to 5 weeks after operations, BBB scale exceed 20, and no significant difference between cAMP groups and control groups by comparing the BBB scales of hindlimb movements. Conclusion cAMP injected in the brain cortex or continuously infused in the spinal lesion area can induce the axonal regeneration and is beneficial to repair the spinal cord injury, but could not directly promote hindlimb movements recovering.