There are only few cases of Eosinophilic Collitis(EC) have been reported worldwide. The mechanism and aetiology of EC are still unclear. We describe a 35 years old man presented with chief complaints of gastrointestinal symptoms. In blood examination, his total IgE and specific IgE to house dust mites were very high. Colonoscopy was done and histological examination from biopsy specimens reported infiltration of lymphoplasmacytic cells and eosinophils, compatible with Eosinophilic colitis. The patient was treated with antihistamine and short course of antibiotics. He was been advised to avoid house dust mites. He was then remained asymptomatic. Our report suggests house dust mites allergy as the causes of EC. Combination of antihistamine, antibiotics and avoidance of house dust mites are helpful in treating EC in this particular case.
House dust mite

This cross-sectional study aims to investigate high-school students’ experiences with exergames, their knowledge, attitudes, and practice of exercise in Pulau Pinang, Malaysia. A relevant questionnaire has been effectively adapted by inserting another section to assess the respondents’ experiences regarding exergames. The modified questionnaire was used as the research instrument in this study. The sampling size consisted of 377 Malaysian high school students in Pulau Pinang, Malaysia. The five-section questionnaire provided statements and questions about the respondents’ sociodemographic data and exergames’ experiences, as well as their knowledge, attitude, and practice of exercise. The time frame was between October 2021 and January 2022. Data were analysed by using descriptive statistics of frequency and percentages. The association between gender, age and experience, knowledge, and attitude was examined using the chi-square test. p value of < 0.05 considered as statistically significant. Based on the quantitative results, 97.9% of the respondents have had adequate knowledge about exercise and 83.6% of the respondents displayed positive exercise attitudes. Approximately, half of the students allocated between 30 and 60 minutes daily to perform moderate-to-vigorous intensity workouts. However, a statistically significant difference was perceived in their experiences of exergames. Specifically, female respondents demonstrated that they have more experience than their male counterparts. Holistic efforts are essential to raise high-school students’ awareness of exercise given its outstanding potential to enable children and adolescents’ physical activity engagement.
Knowledge

ABO blood groups have been associated to increased susceptibility in allergic diseases, including asthma and atopic dermatitis. Although few studies demonstrated the association of ABO blood groups with allergic rhinitis, the evidences are still generally scarce and involved certain population. Therefore, this study aimed to investigate the association of ABO blood groups and allergic rhinitis in the Malaysian population. Further analysis was conducted to investigate the association between ABO blood groups and specific allergens, such as house dust mites, in patients with allergic rhinitis. A total of 163 patients with allergic rhinitis and 163 controls were recruited from AMDI, USM, Penang and HUSM, Kelantan. Blood samples were collected from both groups, and ABO phenotypes were identified using the tube method. The Pearson Chi-square test was employed to determine the association. Statistical significance was set for an alpha error of 5% (p-value < 0.05). O blood was identified as the most common blood group. However, no significant associations of ABO blood groups were observed in the allergic rhinitis patients. The result was also not significant with the O blood group being the highest prevalence and the AB blood group being the least prevalence to house dust mites allergy. This study provides beneficial information for future studies on the predictive role of blood groups in clinical practices. In our study, most of the participants recruited were Malays which might cause genetic bias. Therefore, employing a multi-centered and multiracial approach with larger sample size is recommended for future research.
Rhinitis, Allergic