1.Prevalence Of Low-Back Pain Among Public Ambulance Workers In Kelantan, Malaysia
Engku Ariff Tuan Lonik ; Tuan Hairulnizam Tuan Kamauzaman ; Ariff Arithra Abdullah ; Junainah Nor ; Siti Azrin Ab Hamid
Malaysian Journal of Public Health Medicine 2017;17(1):126-135
This study is to determine the prevalence and the associated factors of low-back pain (LBP), which has multifactorial
causes, among ambulance workers in Kelantan, Malaysia. The cross-sectional study involved ambulance workers in the
emergency department in all government hospitals in Kelantan. Those who did not consent, complete or return the
questionnaire as well as having rheumatic diseases were excluded from the study. The participants were asked to
answer a self-administered questionnaire in English. Descriptive analyses and Chi-square test were used. A total of 168
respondents had completed the questionnaires with a response rate of 85.0%. Questionnaires with more than 95.0%
items completed were included in the analysis (n=143). The respondents had a higher proportion of male than female
(63.6% versus 36.4%). Assistant Medical Officer comprised of 60.0% of all respondents and the rest were nurses. The
respondents’ age ranged between 23 to 58 years old with a mean age of 38.27 and standard deviation (SD) of 7.27. The
mean duration of involvement in ambulance service was 9.68 years (SD 6.97). The majority (98.5%) of the respondents
were Malay. Gender, smoking status and hobbies were the associated factors of LBP among ambulance workers. The
modifiable risk factors should be emphasized to the ambulance workers as a measure to prevent the development of
LBP.
2.Median Survival Time of Endometrial Cancer Patients with Lymphovascular Invasion at the Hospital Universiti Sains Malaysia
Wan Adnan Wan Nor Asyikeen ; Ab Hamid Siti-Azrin ; Nur Asyilla Che Jalil ; Anani Aila Mat Zin ; Nor Hayati Othman
Malaysian Journal of Medical Sciences 2016;23(6):44-51
Background: Endometrial cancer is the most common gynaecologic malignancy among
females worldwide. The purpose of this study was to determine the median survival time of
endometrial cancer patients at the Hospital Universiti Sains Malaysia (USM).
Methods: A list of 121 endometrial cancer cases registered at Hospital USM between 2000
until 2011 was retrospectively reviewed. The survival time of the endometrial cancer patients
was estimated by Kaplan-Meier survival analysis. Log-rank tests were performed to compare the
survival of the patients based on socio-demographics and clinical presentation.
Results: Only 108 patients, 87.0%, were included who were of Malay ethnicity. Previous
history included menopause in 67.6% of patients and diabetes mellitus in 39.8% of patients;
additionally, 63.4% of patients were nulliparous. Tumour staging was as follows: 24.5% stage
I, 10.8% stage II, 26.5% stage III and 38.2% stage IV. The overall median survival time of the
endometrial cancer patients was 70.20 months (95% confidence interval (CI): 51.79, 88.61). The
significant factors were age, the presence of lymphovascular invasion and treatment received.
Conclusion: The overall survival of endometrial cancer was low. A prospective study
needs to be carried out to discover more effective and accurate tests for the early detection of
endometrial cancer.
3.Reporting Statistical Results in Medical Journals
Wan Nor Arifin ; Abdullah Sarimah ; Bachok Norsa’adah ; Yaacob Najib Majdi ; Ab Hamid Siti-Azrin ; Musa Kamarul Imran ; Abd Aziz Aniza ; Lin Naing
Malaysian Journal of Medical Sciences 2016;23(5):1-7
Statistical editors of the Malaysian Journal of Medical Sciences (MJMS) must go through
many submitted manuscripts, focusing on the statistical aspect of the manuscripts. However, the
editors notice myriad styles of reporting the statistical results, which are not standardised among
the authors. This could be due to the lack of clear written instructions on reporting statistics in the
guidelines for authors. The aim of this editorial is to briefly outline reporting methods for several
important and common statistical results. It will also address a number of common mistakes
made by the authors. The editorial will serve as a guideline for authors aiming to publish in the
MJMS as well as in other medical journals.
4.Ultrasound findings of plasma leakage as imaging adjunct in clinical management of dengue fever without warning signs
Xin Tian Chai ; Kamarul Aryffin Baharuddin ; Shaik Farid Abdull Wahab ; Andey Rahman ; Ridzuan Mohd Isa ; Ab Hamid Siti-Azrin
The Medical Journal of Malaysia 2020;75(6):635-641
ed as outpatients. Ultrasonographyevidence of plasma leakage either pleural effusion,thickened gallbladder wall, ascites or pericardial effusionwere compared with clinical findings and laboratoryparameters for plasma leakage. Results: Of the 83 dengue patients, eventually 72.3% haddengue fever with warning signs and 6.0% had severedengue fever. There were 38 patients who had subclinicalplasma leakage at initial presentation, 84.2% and 7.9% ofthem then progressed to dengue fever with warning signsand severe dengue respectively. There was a minimalagreement between serial bedside ultrasound andhaematocrit level in the detection of plasma leakage(observed kappa 0.135). Conclusions: Serial bedside ultrasound is an adjunctprocedure to physical examination and may detect plasmaleakage earlier compared to haemoconcentration. The earlyusage of serial ultrasound is of paramount importance indetecting dengue patients who are at risk of progressing tosevere dengue.
5.Simulation study on quality of CPR between manual chest compression and mechanical chest compression devices performed in ambulance
Tuan Hairulnizam Tuan Kamauzaman ; Johnny Ngu Tai Hock ; Ariff Arithra ; Abu Yazid Md Noh ; Siti-Azrin Ab Hamid ; Junainah Nor
The Medical Journal of Malaysia 2021;76(2):171-176
Background: Maintaining good quality CPR while
transporting out-of-hospital cardiac arrest patients is very
challenging. We aim to determine how different ambulance
speed can affect the quality of chest compression
performed either manually or mechanically.
Methods: This was an observational manikin-based study. A
total of 96 participants as well as two types of mechanical
compression devices: Lucas-2 and AutoPulse, performed
one minute of continuous chest compression on BT-CPEA
programmed manikin while the ambulance travelled at
different speeds, i.e., idle state, 30km/hr and 60km/hr. Seven
outcome variables of chest compression were measured.
Performance data of different groups of compressor were
compared and analysed using repeated measures analysis
of variance (ANOVA).
Results: In manual chest compression, significant variation
were noted among different speeds in term of average
compression rate (p<0.001), average compression depth
(p=0.007), fraction of adequate/insufficient compression
depth and fraction of normal hands positioning with
p=0.018, 0.022 and 0.034 respectively. Overall, AutoPulse
and Lucas-2 were not affected by ambulance speed. Lucas2 showed more consistent average compression rate, higher
fraction of adequate compression depth and reduced
fraction of insufficient compression depth as compared to
manual compression with p<0.001, 0.001 and 0.043
respectively.
Conclusion: In this study we found that ambulance speed
significantly affected certain aspects of manual chest
compression most notably compression depth, rate and
hand positioning. AutoPulse and Lucas-2 can improve these
aspects by providing more consistent compression rate,
depth and fraction of adequate compression depth during
transport.
6.Burnout Among Caretakers of Paediatric Patient with Chronic Kidney Disease
Norsarwany Mohamad ; Mohd Ikram Ilias ; Siti Azrin Ab Hamid ; Suria Emilia Suhana Othman Tan ; Siti Nur Haidar Hazlan
Malaysian Journal of Medicine and Health Sciences 2022;18(No.4):89-95
Introduction: Caring for children who have chronic kidney disease (CKD) is challenging. The goal of this study was
to find out the prevalence of burnout and what factors contribute to it. We also want to know the correlation between caretaker’s strain and burnout. Methods: This was a cross-sectional study that involved caretakers of children
with CKD. They were recruited from a university hospital in Kelantan, Malaysia. Self-administered questionnaire in
Malay language comprised of Demographic Information Form, Copenhagen Burnout Inventory (CBI-M) and Caregiver Strain Index (CSI-M) was used. Results: Eighty-eight caretakers were involved in this study. The mean age of
caretakers was 42 years old, majority were female (72.4%), Malay (99.0%) and Muslim (99.0%). The mean age of
children with CKD was 11 years old, most of them were on medication (69.3%) and mean duration of illness was
4.6 years. The prevalence of burnout in all domains (personal, work-related, client-related) among the caretakers
was 5.7%. Eight caretakers had personal burnout (9.1%) while five (5.7%) had client-related and work-related burnout respectively. Multiple linear regression showed positive association of duration since the initial diagnosis and
total ward admission within six months with total burnout score. Pearson correlation revealed a positive and fair
correlation between strain and burnout. Conclusion: Prevalence of burnout among caretakers was generally low, but
personal burnout outnumbered other domains. Children with CKD with longer duration of illness and more frequent
ward admission are the important factors leading to burnout among caretakers. A high number of caretakers having
significant strain indicated that there were possibilities of developing burnout later on.
7.Antioxidant Enzymes in Tears Among Malay Age-related Macular Degeneration Patients
Yi Ni Koh ; Embong Zunaina ; Ahmad Tajudin Liza-Sharmini ; Che Badariah Abd-Aziz ; Che Hussin Che-Maraina ; Mei Fong Chong ; Berahim@Ab Rahman Azriani ; Ab Hamid Siti-Azrin ; Sarina Sulong
Malaysian Journal of Medicine and Health Sciences 2020;16(No.2):149-156
Introduction: Age-related macular degeneration (ARMD) is an ocular degenerative disorder that associated with impairment of central vision. Oxidative stress plays an important role in the pathogenesis of ARMD. The aim of this study was to determine the level of antioxidant enzymes (catalase and glutathione peroxidase) in tears among Malay ARMD patients. Methods: A cross sectional study was conducted between September 2015 and November 2017 among Malay ARMD patients. Schirmer paper was used to collect the tear samples. The level of catalase and glutathione peroxidase level in tears was evaluated using commercially available oxidative stress marker kits. Results: A total of 136 Malay ARMD patients were recruited into the study with 68 controls. Mean tear catalase and glutathione peroxidase levels were significantly lower in ARMD patients (1348.97 SD 109.11 µM and 453.87 SD 41.96 U/L respectively) as compared to the control group (1453.38 SD 38.87 µM and 502.28 SD 34.29 U/L respectively) (P<0.001 and P<0.001 respectively). Late ARMD has lower mean of catalase level in tears as compared to early ARMD (P=0.044). Based on subtypes of neovascular late ARMD, neovascular ARMD has lower mean catalase level in tears compared to idiopathic polypoidal choroidal vasculopathy (IPCV) (P=0.031). Conclusion: This study showed that antioxidant enzyme might play an important factor in the pathogenesis of ARMD.
8.Cytogenetic Abnormalities at Diagnosis and During Follow Up in Multiple Myeloma Patients and Their Prognostic Implications - A Preliminary Report
Eva Foong ; Ismail Siti-Mariam ; Ramli Norhidayah ; Abu Bakar Zulaikha ; Mat Zin Nik-Mohd-Zulfikri ; Mohd Nawi Nurul-Alia ; Annuar Aziati ; Mohd Yunus Nazihah ; Nik Mohd Zaid Nik-Ahmad-Hilmi ; Husin Azlan ; Ab Hamid Siti-Azrin ; Azman Fatimah ; Ravindran Ankathil
Malaysian Journal of Medicine and Health Sciences 2020;16(No.4):108-117