We aimed to investigate the incidence, fatality, and associated factors in patients with hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) hospitalized for coronavirus disease 2019 (COVID-19) infection and reimbursed from the National Health Security Office (NHSO). Methods: The retrospective cohort analysis was conducted from an electronic-claimed database, and COVID-19 vaccination status was evaluated in patients with HD, PD, and KT from January 2020 to December 2021. There were 85,305 patients reimbursed for HD, PD, and KT by the NHSO. The rates of COVID-19 infection, COVID-19 vaccination, comorbidities, fatalities, and the cost of treatment were evaluated. Results: COVID-19 infection was observed in 1,799 of 36,982 HD cases (4.9%), 1,531 of 45,453 PD cases (3.4%), and 95 of 2,870 KT cases (3.3%). Patients receiving COVID-19 vaccinations were most common in the KT group, followed by those with HD and PD (76.93% vs. 70.65% vs. 51.34%, respectively). KT patients had a lower fatality rate compared to those with PD and HD (8.42% vs. 18.41% vs. 21.40%, respectively). Advanced age, diabetes, cardiovascular diseases, and COVID-19 vaccination status were associated with fatality. The adjusted odds ratios of fatality after receiving one or two doses of vaccines were 0.7 (95% confidence interval [CI], 0.6–0.9) and 0.3 (95% CI, 0.2–0.4), respectively. The cost of treatment was highest in patients with HD, followed by PD and KT. Conclusion: The incidence of COVID-19 infection was higher in patients with HD than in those with PD or KT. COVID-19 vaccination following the national health policy should be encouraged for these patients to prevent fatality.

Introduction: Patients with peritoneal dialysis (PD) who develop volume overload (VO) have high risks of dropout from death or advancement to hemodialysis. We aimed to determine the mortality rates, associated factors, and patient survival rates of PD patients who had history of admission from VO. Methods: We reviewed data of PD patients who were registered in the Database of Peritoneal dialysis in EXcel (DPEX) from January 2008 to December 2018. They were followed until death or the end of June 2020. Patients with at least 18 years of age and history of admission from VO were classified into two groups. Group A had a history of VO after starting PD. Group B had a history of VO before and after starting PD. The mortality rates were calculated. Patient survival and associated factors were evaluated by Kaplan-Meier and multiple cox regression, respectively. Results: 1,882 patients had history of admission from VO. The overall mortality rate was 28.9 per 100 person-years. The mortality rates in group A and group B were 25.4 and 41.7 per 100 person-years, respectively. Patients in group A had lower age, fewer comorbidities, longer dialysis vintage, and better patient survival than those in group B. Factors related to worsening patient survival were increased age, diabetes, and comorbidities. Conclusion: Patients with history of admission from VO before and after the start of PD had higher mortality rates than those with history of admission from VO after PD. Increased age, diabetes, and comorbidities were the associated factors of patient survival.