1.Advancement on standardization of clinical laboratory information
Lei XU ; Jia HE ; Sichang FAN ; Xiaob HU
Academic Journal of Second Military Medical University 1985;0(06):-
The standardization of clinical laboratory information is an important part of standardization of medical infor-mation,and the critical means to realize this standardiaztion is to classify and code the clinical laboratory items.Earlier work has been done mainly in the United States,Europe and Japan.However,it develops later in China.Although we have had our standard,there are still some problems to be resolved.In this article,we retrospectively reviewed and compared the main contents,coding methods,standard form and applications,etc.in the above countries and regions,providing some ideas for improving the standardization of clinical laboratory information in China.[
2.Construction of WeChat public platform in class A hospitals affiliated to Sichuan Province in Chengdu
Xin XU ; Zhihui LIU ; Daren ZHAO ; Sichang HE ; Ruihua ZHANG
Chinese Journal of Medical Library and Information Science 2016;25(9):68-73
Objective To investigate the current situation in construction of WeChat public platform in 9 class A hospitals affiliated to Sichuan Province in Chengdu. Methods The problems and the reasons why they occurred in construction of WeChat public platform in these 9 hospitals were analyzed by literature analysis, interview, Topsis and RSR analysis, and their combination. Results The problems found in hospital WeChat public platform included imperfect management, unmatched construction level and hospital scale, insufficient government policy support and effective supervising mechanisms. Conclusion Hospitals should strengthen the construction and management of their WeChat public platform, innovatively construct their WeChat public platform, win over sufficient government policy support, and improve their supervising mechanisms.
3.Clinical features of primary bilateral macronodular adrenal hyperplasia
Weiwei ZHOU ; Tingwei SU ; Yu ZHU ; Lei JIANG ; Fukang SUN ; Yiran JIANG ; Jun DAI ; Cui ZHANG ; Hongchao HE ; Xu ZHONG ; Luming WU ; Sichang ZHENG ; Weiqing WANG
Chinese Journal of Endocrinology and Metabolism 2023;39(12):1023-1027
Objective:To investigate the clinical profile of primary bilateral macronodular adrenal hyperplasia(PBMAH) and sex difference.Methods:One hundred and forty cases of PBMAH were recruited in our center from 2014, and all patients were evaluated for hormone secretion, adrenal imaging, and metabolic parameters.Results:Overt Cushing′s syndrome accounted for 76.4% of PBMAH cohort and 47.9% were female. The overt group had higher serum cortisol and 24 h urinary free cortisol levels, lower adrenocorticotropic hormone, higher serum cortisol after low-dose dexamethasone suppression tests, larger total adrenal size, and a higher percentage of obesity, hypertension, diabetes mellitus, and hypokalemia than the subclinical group(all P<0.05). When compared with the male group, the female group had smaller adrenal size( P<0.001), lower HbA 1C( P=0.003), higher total cholesterol( P=0.005), and lower density lipoprotein-cholesterol levels( P=0.035). Further, 24 h urinary free cortisol in the male group was found to be positively correlated with diastolic blood pressure, fasting glucose, 2 h postprandial glucose after oral glucose tolerance test(OGTT), and HbA 1C after adjusted for age, body mass index, and onset duration, and was negatively correlated with body mass index and potassium levels. While 24 h urinary free cortisol in the female group was positively correlated only with diastolic blood pressure, fasting glucose, and 2 h postprandial glucose after OGTT(all P<0.05). During follow-up, 80.0% of patients achieved remission after unilateral adrenalectomy, with a recurrence rate of 17.9%. Conclusion:PBMAH related metabolic disorder is more pronounced in overt Cushing′s syndrome and males. Unilateral adrenalectomy as an effective treatment can benefit the majority of patients.