1.Palliative resection of advanced primary hepatocellular carcinoma
Yunfu LI ; Guanrui YE ; Meirong LI ; Yanjin HUANG ; Sibo PAN
Chinese Journal of General Surgery 2001;10(2):120-122
Objective To evaluate the effect of palliative resection of advanced primary hepatocellular carcinoma (PHCC). Methods 98 patients with advanced PHCC were divided randomly into two groups in our hospital from March 1996 to Jan. 2000:(1) Therapy group (49 cases), dealt with palliative resection of liver cancer and implanted with a drug delivery system (DDS). (2) Control group (49 cases), only implanted with DDS. Results In therapy group and control group, The decline rate of AFP was 60.0% and 31.7% respectively (P<0.05); and the survival rates of 0.5, 1, 3 years after operation were 85.7% (42/49), 60.5%(23/38), 45.4%(10/22) and 67.3%(33/49), 32.5%(13/40), 10%(2/20) (P<0.05). Conclusions Palliative resection of liver cancer can improve survival duration and life quality of patients with advanced HCC.
2.Comparative analysis of allogeneic bone pad and autogenous bone graft in anterior cervical interbody fusion
Weiji WANG ; Yucheng GUAN ; Xilin GAO ; Minghua JI ; Shuzhang GUO ; Xiangcheng FAN ; Sibo YE
Chinese Journal of Tissue Engineering Research 2014;(39):6252-6257
BACKGROUND:Surgical treatment is often required for fractures of the cervical vertebrae. Anterior interbody fusion technology is stil the main method for the treatment of cervical degeneration or traumatic instability. Here, the self-made oval al ogeneic bone pad can adapt to different height and width of the intervertebral space, in line with the physiological shape of the intervertebral space. OBJECTIVE:By comparison with autogenous iliac crest bone, to evaluate various types of self-designed al ogeneic bone pads on anterior cervical interbody fusion. METHODS:From January 2009 to December 2013, 58 patients with cervical disc herniation were enrol ed and subjected to cervical discectomy and anterior cervical interbody fusion. According to different bone grafts, these patients were divided into al ogeneic bone pad and autogenous iliac bone groups. The course of disease was 12 to 24 months. The postoperative effect was measured by Japanese Orthopaedic Association (JOA) score, cervical fusion rate, fusion time, operative time, blood loss and rejection rate. RESULTS AND CONCLUSION:At 6 months postoperatively, the JOA score of two groups had no significant difference at 6 months after treatment (P>0.05);the cervical fusion rates were 83.7%and 87.8%, respectively, in the al ogeneic bone pad and autogenous iliac bone groups, with no significant difference (P>0.05). Fusion time was higher in the al ogeneic bone pad than in the autogenous iliac bone group (P<0.05). The internal fixators in the two groups were firmed without loosening, and there was no rejection during the fol ow-up. Compared with the autogenous iliac crest bone, anterior cervical interbody fusion with al ogeneic bone pad can achieve satisfactory effects, which can be better for intervertebral fusion and cannot induce pain due to bone cutting.
3.Combined superselective transcatheter arterial chemoembolization and selective intraportal venous embolization for the treatment of inoperable advanced primary liver cancer
Meirong LI ; Guanrui YE ; Huadong CHEN ; Yunfu LI ; Sibo PAN ; Yanjin HUANG ; Qinshou CHEN ; Yongren LIANG
Chinese Journal of General Surgery 1993;0(01):-
Objective To evaluate superselective transcatheter arterial chemoembolization ( TACE) plus selective portal vein embolization (SPVE) and large dose of lipiodol on advanced primary liver carcinoma (PHC).Methods Two hundred and three cases of advanced PHC were randomly divided into group treated with ordinary TACE, and that with TACE +SPVE. Results The response rate (CR+PR) was 38% in TACE group and 59% in TACE+SPVE group (P
4.Complete mesocolic excision in laparoscopy-assisted right hemicolon carcinoma radical resection
Xingfeng QIU ; Zhijian YE ; Feng YAN ; Li LIN ; Sibo YUAN ; Zhijie DING ; Zhenfa WANG ; Zhongquan QI ; Zhongchen LIU
Chinese Journal of General Surgery 2012;27(3):213-215
Objective To evaluate complete mesocolic excision in laparoscopy-assisted right hemicolon carcinoma radical resection. Methods Laparoscopy-assisted right hemicolon carcinoma radical resection with complete right-side mesocolic excision was performed in 36 cases between June 2010 and July 2011 at Zhongshan Hospital,Xiamen University. Results The operations were completed successfully without conversion to open surgery.The mean operative time was (134 ±22) min.The blood loss was (95 ±53 ) ml.The median number of total lymph nodes removed was 15.7.The average time for passage of flatus was (3.1 ± 1.2) d.The postoperative complications were observed in 6 of 36 cases (17%) including lymphatic fistulas in 4 patients,pulmonary infection in 1 patient and postoperative bleeding in 1 case.Conclusions Laparoscopy-assisted complete right-side mesocohc excision can be successfully performed for right hemicolon carcinoma,and the lymphoid tissue could be eliminated maximally.The long-term results need further evaluation.