4.Large artery intracranial occlusive disease
Si CHEN ; Song TAN ; Yuming XU
International Journal of Cerebrovascular Diseases 2012;20(4):274-277
Large artery intracranial occlusive disease is a important and common vascular lesion type.It is closcly associated with the onset and recurrence of ischemic stroke; however,at present there are many inadequacies in the study of its etiology and treatment.This article mainly reviews the understanding process of the large artery intracranial occlusive disease,present research results and problems need to be solved.
5.The safety and efficacy of Shuxuetong in treatment of paroxysmal atrial fibrillation in patients with chronic pulmonary heart disease
Jianling GU ; Si CHEN ; Kelei XU
Tianjin Medical Journal 2016;44(2):244-246
Objective To observe the clinical efficacy and safety of Shuxuetong in treatment of paroxysmal atrial fibril-lation in patients with chronic pulmonary heart disease. Methods A randomized single-blinded study was performed. A to-tal of 91 patients with paroxysmal atrial fibrillation and chronic pulmonary heart disease were randomly divided into treat-ment group (n=45) and control group (n=46). The treatment group was received Shuxuetong and clopidogrel treatment for 14 days. The control group was given routine treatment plus clopidogrel 75 mg orally. The average time of cardioversion of parox-ysmal atrial fibrillation was detected within 48 hours. The cardioversion rate of paroxysmal atrial fibrillation and the total effi-ciency were detected after14 days. The serum D-Dimer was detected before and 14 days after treatment . Liver and kidney function and adverse drug reactions were also detected. Results There was no significant difference in average time of car-dioversion of paroxysmal atrial fibrillation in 48 h between two groups (h:12.62±2.32 vs 13.32±2.25,t=1.461). The cardiover-sion rates were 86.67%(39/45) and 82.22%(37/45) at 48 h and 14 d in treatment group, which were significantly higher than those of control group [69.56%(32/46) and 60.87(28/46)]. The D-Dimer at 14 d after treatment was significantly lower in treatment group [(2.05±0.34)mg/L] than before treatment[(2.61±0.27)mg/L], also than that of control group[(2.53±0.31)mg/L]. There were no abnormal liver and kidney function and no adverse reactions between two groups. Conclusion Shuxuetong can significantly prevent the recurrence of paroxysmal atrial fibrillation in patients with chronic pulmonary heart disease, and help to reduce the risk of thromboembolism. It is safe and effective.
6.Psychology study and analysis of cleft palate patients after operation
Haiyan ZHOU ; Xuguang XU ; Zhuang SI
Journal of Practical Stomatology 2001;0(03):-
Objective:To study the effect of articulation disorder on psychology action of cleft palate patients after operation.Methods:65 patients were asked to answer the psychology questionnaire.Results:The patients of misarticulation all have some degree of psychological disability,and unusual psychology action would affect pronunciation treatment.Conclusion:Patients with misarticulation have psychology problems in some degree,which would affect the clinic treatment of cleft palate.
7.Investigation of Indoor Air Microorganism Pollution in Campus
Dongxia SI ; Bingrong XU ; Min ZHANG
Journal of Environment and Health 1989;0(06):-
Objective To understand the microorganism pollution in the indoor air in the campus of Liaocheng University. Methods In April and May, 2004, the content of airborne microbes in the indoor air in Liaocheng University campus was determined by the gravity plate method. Results The average content of bacteria in the indoor air was 2.39?103 cfu/m3, the average content of mildew was 0.62?103 cfu/m3. The predominant microorganism in the internet bars in the campus was bacteria. Conclusion In general, the indoor air quality in Liaocheng University campus is at comparative clear level.
8.THE EFFECT OF POLYACTIA B ON TUMOR-INFILTRATING IMMUNOCOMPETENT CELLS WITIHN MURINE S_(180) SARCOMA
Changfu XU ; Lusheng SI ; Liang FANG
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(03):-
Polyactin B (Pb) has been proved to have the effect of considerable tumor suppression. Recently,we used murine S_(180) Sarcoma as a model and observed the effect of Pb on the tumor—infiltrating immunocompetent cells, and also the infiltrating neutrophils and the alteration of small blood vessels within the tumor tissue. Compared with control: in Pb—treated group, there were more L_3T_4~+and Lyt_2~+ lymphocytes infiltrating in the periphery of the tumor ,and also within the tumor. In addition, the tumors had more prominant hyperemia, micro—thrombosis and neutrophil infiltration around the necrotic areas. The present findings suggest that the tumor—suppression effect of Pb might be mediated through TNF produced by immunocompetent cells.
9.Relationship of caspase-3 activity and cardiac function in rat cardiomyocytes after myocardial reperfusion injury
Qiang XU ; Liangyi SI ; Hong ZHANG
Journal of Third Military Medical University 2003;0(23):-
Objective To investigate the correlation between caspase-3 and left ventricular function at different phases after ischemia-reperfusion. Methods Totally 36 wistar rats were randomly divided into Sham operation group and ischemia-reperfusion(IR)group. The rat ischemic cardiac region of IR group was taken after 1, 3, 6, 12 and 24-hour reperfusion followed to 30-minute ischemia and detected for the activity fragment of caspase-3 P20, the activity of caspase-3, myocardial apoptosis index, left ventricular function (LVF) and creatine kinase-MB (CK-MB) respectively. Results With reperfusion time prolonging, the activity fragment of caspase-3 P20 increased, the activity of caspase-3, myocardial apoptosis index, left ventricular function and CK-MB all changed. The activity fragment of caspase-3 P20 and CK-MB peaked at 6 h, and the activity of caspase-3 and myocardial apoptosis index at 12 h, and then maintained platform; LVSP and ?dp/dt_max increased while LVEDP decreased gradually with the reperfusion time prolonging. All indexes mentioned above of IR group had statistical significance as compared with that of Sham operation group(P
10.Diagnosis and treatment of hydatidosis of retroperitoneum and bladder (Report of 9 cases)
Jianye XU ; Hongbing SI ; Dayong LIANG
Journal of Clinical Surgery 2001;0(01):-
Objective To investigate the diagnosis and treatment of Hydatidosis of post-peritoneum and bladder.Methods Nine cases were reported. Among them,one was epinephros-hydatid cyst,two renal hydated cyst,two hydatidosis of post-peritoneum in ileopelvic, and four bladder hydrated cyst. All cases had history of contacting with dog or sheep.Results All of the nine cases were cured by operation. Conclusions In percussion of the lower abdominal mass, hydrated cyst vibration, a specific sign, can usually be felt; and the mass do not disappear after urination. Besides, E-immune Test for echinococcus, B-ultrasonography, and CT are very useful diagnostic methods. Therefore, excision of the cyst still is the only effective treatment for hydatidosis.