3.CT Diagnosis of Ependymoma
Guangyan SI ; Guangcai TANG ; Huixi LV
Chinese Journal of Medical Imaging Technology 2001;17(3):215-216
Objective To analyse the CT appearance of ependymomas and to improve the accuracy of diagnosis. Methods To review the CT appearance of 15 cases of ependymoma that confirmed by surgery and pathology. Results 12 cases were superior, 8 cases were brain parenchyma among of them; 3 cases were subtentorial, among them the fourth ventricle 2 cases. The age of 6 cases vary from 20 to 35 years. Ependymomas superior to the tentorium in the brain parenchyma were the most common, and in malignant parts there were cystoid changes and edema around the tumor. In the other parts were largely solid neoplasm. On unenhanced CT, the solid parts were indense and caicificable and were easy to dicern on enhanced CT . Conclusion The CT appearances of ependymoma were specific, we can dram an accurate conclusion according where the tumor taking place, the age etc.
4.Effects of electrical stimulation on motor function and the expressions of microtubule-associated protein-2 and survivin after cerebral infarction in rats
Xiuqing ZHANG ; Zhihua SI ; Jiyou TANG
Chinese Journal of Physical Medicine and Rehabilitation 2009;31(8):514-518
Objective To investigate the effects of unilateral and bilateral electrical stimulation of the upper and lower limbs on motor function following cerebral infarction and the expressions of microtubule-associated protein-2 (MAP-2) and survivin in the infarction border zone of rats. Methods Adult male Sprague-Dawley (SD) rats were randomly divided into sham operation, control, impaired limb and bilateral limbs electrical stimulation groups (each group included 32 rats). Acute cerebral infarction was mimicked using a middle cerebral artery occlusion tech-nique. After cerebral infarction for 24 h, the rats were treated daily with or without electrical stimulation. A beam walking test (BWT) was used to measure limbs motor function and immunohistochemistry and HE staining were used to detect the expressions of MAP-2 and survivin in the border zone of infarcted area after electrical stimulation treat-ment for 3, 7, 14 and 21 d. Results Comparet with the control group treatment with electric stimulation led to BWT scores increasing significantly, and bilateral stimulation was more potent in ameliorating motor function thanstimulating the impaired limb only. The expression of MAP-2 was significantly higher in eleetrieal stimulation groups than in control group from the 7th of treatment, and it was higher in bilateral stimulation group than that in unilateral stimulation group from tbe 14th day of treatment. There was no significant difference in MAP-2 expression between bi-lateral stimulation group and sham operation group at the 21st day of treatment. In electrical stimulation groups, at every time point the expressions of survivin were obviously higher than that in sham operation group, and it was higher than that in control group and peaked at the 7tb and 14th day of treatment and in bilateral stimulation group it was no-tably higher than that in unilateral stimulation group. At the 21st d of treatment the level of survivin expression drop-per; however, there was no significant difference between unilateral and bilateral electrical stimulation groups. Con-clusions Treatment with electrical stimulation, particularly in bilateral limbs stimulation, could induce MAP-2 and survivin expressions in the infarction border zone of rats. It also could promote the recovery of motor function in para-lyzed limbs after cerebral infarction of rats. The improvement might involve the up-regulation of MAP-2 and survivin expressions.
5.MEASUREMENT OF EXCITABILITY OF VARIOUS FIBERS IN PERONEUS NERVE IN RABBITS STANDARD ELECTRICAL QUANTITY (a) AS AN ACTUAL INDEX FOR MEASURING EXCITABILITY
Jingshi TANG ; Wenchun SI ; Zonglian HOU ;
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
Standard electrical quantity (a), chronaxie (?), rheobase (Rh), "b" in Weiss' formula and intensity threshold of duration being 40 ?s and 300 ?s (T_(?) and T_(200)) were measured on peroneus nerves in rabbits. The results show that "a" is an actual index for measuring the excitability of various groups of fibers. The larger fibers, the higher excitability and the smaller "a" values. "b" does not indicate excitability. "?" , "Rh" , "T_(40)" and "T_(200)" are not actual indexes for measuring excitability because they are influenced by "b" in Weiss' formula.
6.Effects of electric stimulation treatment on motor function and expression of microtubule-associated protein-2 and survivin of brain tissue in cerebral infarction rats
Zhihua SI ; Xiuqing ZHANG ; Jiyou TANG
Journal of Clinical Neurology 1988;0(02):-
Objective To investigate the effects of electric stimulation on motor function and expression of microtubule-associated protein-2(MAP-2) and survivin of brain tissue in the cerebral infarction rats.Methods Cerebral infarction rat models were made using middle cerebral artery occlusion.After cerebral infarction for 24 h,the rats were respectively treated with electric stimulation on paralyzed(unilateral)or bilateral limbs for 3 d,7 d,14 d,21 d.By using beam walking test(BWT) and immunehistochemistry,the motor function and the expression of MAP-2 and survivin of brain tissue in the border of cerebral infarction area were examined at various time following treatment.Results Compared to control group,the electric stimulation groups showed significant increase in BWT scores after treatment 7 d(all P0.05).In the electric stimulation groups,the expression of survivin of brain tissue were obviously higher than those in the sham operation group at various time points(all P0.05).Conclusions Treatment with electric stimulation,in particular bilateral electric stimulation,can promote the recovery of motor function of paralyzed limbs and induce up-regulation of expression of MAP-2 and survivin in the brain tissue of cerebral infarction rats.
7.Study on the mechanism of P2X receptors involved in electroacupuncture treatment of neuropathic pain in dorsal root ganglion and spinal cord
Shuhan SI ; Wenchao TANG ; Fan WANG
Journal of Acupuncture and Tuina Science 2023;21(6):512-520
Neuropathic pain(NP)is directly caused by lesions or diseases of the somatosensory system.It can be attributed to a variety of causes and has a complex pathological mechanism.Purinergic P2X receptors play a critical role in NP.P2X receptors will be activated by the extracellular adenosine triphosphate(ATP)to mediate the pain when the tissue is damaged.In vertebrates,there are 7 subtypes of P2X receptors(P2X1-7)encoded by genes,among which the receptors of P2X3,P2X4,and P2X7 are closely related to NP.Acupuncture produces good therapeutic efficacy on NP.To explore the mechanism of purinergic signaling involved in acupuncture analgesia,a review of the actions of P2X3,P2X4,and P2X7 receptors in acupuncture for NP was conducted.The P2X3 receptor is specifically expressed in small-and moderate-sized neurons in the dorsal root ganglion of the primary afferent nerve and trigeminal ganglion.Acupuncture can directly mediate analgesia by down-regulating the expression of P2X3 receptor in neurons.P2X4 and P2X7 receptors mainly exist in the spinal microglia.Acupuncture can inhibit the nociceptive transmission of substantia gelatinosa neurons by regulating P2X4 receptor in spinal microglia.Moreover,acupuncture may alleviate NP by inhibiting the secretion of inflammatory factors by reducing P2X7 receptor in the spinal microglia.
9.The study on immunological function of B cells in regular volunter blood donor
Si TANG ; Haifeng YANG ; Wen XIONG ; Zhen LI
Chinese Journal of Immunology 2000;0(08):-
0.05).Conclusion:People adjust the immunological function of B cells to normal level in blood donation plastochrone.These undoubtedly provide powerfully experimental data on the enlistment of volunter blood donation.
10.Cost - effectiveness Analysis of Levof loxacin in Treating Lower Respiratory Tract Infections: Survey of 2 Dose Regimen
Jie LUAN ; Xiaohui WANG ; Ying TANG ; Shouchun WANG ; Kaiying SI
China Pharmacy 2005;0(21):-
0.05), respectively; the costs were 640.50yuan and 1 151.21yuan, respectively; the cost-effectiveness ratios were 7.01 and 12.28, respectively; the incremental cost-effectiveness ratio of Group B versus Group A was 220.1. CONCLUSION: The sequential therapy of levofloxacin is preferable in the treatment of lower respiratory infection.