Objective To explore the clinical significance of lantus plus acarbose applied for the treatment of elderly diabetes patieats.Methods 84 old diabetes patients treated in our hospital were randomly divided into experimental group and control group. The patients of experimental group were treated with lantus plus acarbose, the control group used normal insulin. To observe the therapeutic effect of two groups. Results The levels of fasting plasma glucose,2 hours postprandial glucose,glycosylated hemoglobin A1C and the occurrence of adverse reactions after the treatment were statistically significant ( P ＜ 0. 05 ). Conclusion Lantus plus acarbose was an effective treatment for elderly diabetes patients, and could obtain the ideal blood sugar and less complications, and clinical effect of the therapy was ideal, and it was worth used widely.

Objective To evaluate effects of flush fluid of different temperatures on pain, comfort and adverse reactions in patients receiving choledochoscopy via T tube for residual bile duct stones. Methods Patients who underwent choledochoscopy were divided into the experimental group ( 36℃ saline was used as flush fluid) and control group ( room temperature saline was used as flush fluid) randomly. Pain degree, comfort degree, procedure time, the total amount of flush fluid, infusion speed and adverse reactions were recorded and analyzed. Results A total of 100 cases were included, 50 cases in each group. There was no significant difference between the two groups in their education level, working condition, operation methods, T-tube size, necessity for lithotripsy, procedure time, total amount of flush fluid and infusion speed (all P>0. 05). The pain scores were 1. 0(1. 00, 2. 00) and 2. 0(1. 00, 3. 25) (Z=-2. 158,P=0. 031) and the comfort scores were 6. 0(5. 00, 7. 25) and 5. 0(2. 00, 6. 00) (Z=-3. 384,P=0. 001) in the experimental group and the control group, respectively. There was significant difference in the change rate of heart rate during and before procedure between the two groups (-4. 07％± 10. 76％ VS 0. 30％± 10. 23％, P=0. 046) . The incidence of postoperative diarrhea in the experimental group and the control group was 6％( 3/50) and 22％ ( 11/50 ) , respectively (χ2=5. 316, P=0. 021 ) . Conclusion 36℃ saline flush can reduce pain scores, improve comfort degree and reduce the incidence of postoperative diarrhea after procedure in patients undergoing choledochoscopy via T tube.