1.Epidemiology of inpatients with fractures and its effect on health education
Lanshu ZHOU ; Shuzhen LI ; Anli JIANG
Chinese Journal of Nursing 2001;36(1):13-15
Objective:To study the epidemiology of inpatients with fractures and discuss its effect on health education.Methods:Therer were 6290 inpatie nts with fracture investigated retrospectively.FoxPro and SPSS were used for statistical analysis.Results:The mean age of the patients was 41.03±20.05 years.The fraction male to female patients was 2.39:1.The mean hospitalized days were 24.11±22.73 days (±s).A majority(63.5%) of the patients were admitted to the hospital by emerg ency.Fractures in 15 parts accounted for 70% of total fractures in 6 hospital, 7 of which accounted for more than 50% of total fractures in each hospital.Discussion:Health education should be carried out according to risk factors as well as age and gender.The devel opment of the model,which combines prevention,first-aid and rehabilitation,is t he trend of health education for fractures.The basic knowledge of fractures in these 15 parts should be learned by orthopedic nurses.Patient education should be carried out individually.The hospital's situation should also be considered.
2.Retrospective study of postoperative odynophagia in elderly patients undergoing intraoperative transoesophageal echocardiography examination for cardiac surgery
Hui YU ; Shuzhen ZHOU ; Mingzhang ZUO
Chinese Journal of Geriatrics 2013;32(10):1098-1100
Objective To evaluate the influencing factors for postoperative odynophagia in elderly patients undergoing intraoperative transesophageal echocardiography (TEE) examination for cardiac surgery.Methods A total of 96 patients with intraoperative TEE examination for cardiac surgery was divided into two groups:the elderly group (patients aged ≥65 years,n=60) and the young group (patients aged < 65 years,n =36).Clinical data were retrospectively analyzed.Postoperative odynophagia was assessed by number rating scale (NRS) scores.Characteristics of postoperative odynophagia were compared between the two groups.Influencing factors for postoperative odynophagia were analyzed by multivariable logistic regression analysis.Results The incidence of postoperative odynophagia and the average NRS score were higher in the elderly group thanin the young group [88.3% vs.66.7%,(2.6±1.7) vs.(1.4±0.9),P<0.05 or 0.01].Multivariate logistic regression analysis showed that preoperative oral lidocaine plasmagel,oropharyngeal mucosal injury and duration of TEE insertion were independent influencing factors for postoperative odynophagia (all P<0.01).Conclusions The incidence of postoperative odynophagia is higher and the degree of odynophagia is more serious in elderly patients undergoing intraoperative TEE examination for cardiac surgery.Postoperative odynophagia can be relieved by applying the preoperative oral lidocaine plasmagel,reducing oropharyngeal mucosal injury and shortening the duration of TEE insertion.
3.Effect of neuromuscular block on airway sealing pressure of laryngeal mask airway i-gel in patients undergoing general anesthesia
Shuzhen ZHOU ; Ruifang JIA ; Mingzhang ZUO
Chinese Journal of Anesthesiology 2014;34(4):392-394
Objective To evaluate the effect of neuromuscular block on the airway sealing pressure of laryngeal mask airway (LMA) i-gel in patients undergoing general anesthesia.Methods Sixty patients scheduled for elective surgery under general anesthesia with LMA i-gel were randomly allocated to one of three groups (n =20 each):control group (group C),rocuronium 0.3 mg/kg group (group R1) and rocuronium 0.6 mg/kg group (group R2).Anesthesia was induced with target-controlled infusion of propofol and remifentanil.The target plasma concentration of propofol was 3.5 μg/ml,and the target effect-site concentration of remifentanil was 3.0 ng/ml.When the patients lost consciousness and after the target plasma and effect-site concentrations were balanced,LMA i-gel was inserted to perform mechanical ventilation.After insertion of LMA i-gel,rocuronium 0.3 and 0.6 mg/kg were injected in R1 and R2 groups,respectively.The airway sealing pressure of LMA i-gel was detected immediately after insertion of LMA i-gel and at 1 min after administration of rocuronium.Results There was no significant difference in the airway sealing pressure of LMA i-gel between groups and within groups(P > 0.05).Conclusion Neuromuscular block has no significant effect on the airway sealing pressure of LMA i-gel in patients undergoing general anesthesia.
4.Brain oxygen supply-demand balance status in patients with total intravenous anesthesia and spontaneous respiration during brain stem neoplasm surgery
Xiaoli ZHOU ; Shuzhen ZHANG ; Enzhen WANG
Chinese Journal of Anesthesiology 1994;0(01):-
Objective: To observe the effects of total intravenous anesthesia(TIVA)and spontaneous respiration on brain oxygen balance status in patients undergoing brain stem neoplasm resection. Method: Thirty patients,ASA grade Ⅰ-Ⅱ, received endotracheal intubation with spontaneous respiration and TIVA. TIVA was maintained with intravenous 0.2% lidocaine 2-3mg?kg~(-1). h~(-1),0.4% propofol 4-6mg?kg~(-1),h~(-1)and 1% ketamine 1-1.5mg?kg~(-1). h~(-1). Arterial and jugular bulb blood samples were taken before and after induction,sawing skull and removing trmor seperately to analyse blood gas. According to Fick principle, the level of CaO_2,CjvO_2 and C (a-jv)O_2 were calculated. Result:The hymodynamics, SaO_2 and CaO_2 remained stable during whole procedure. In comparison with the baselines. respiratory rate, minute volume, arterial blood pH and C(a-jv)O_2 were decreased, and PaCO_2.SjvO_2, and CjvO_2 were increased significantly (P
5.Effects of isoflurane inhalation on the electroencephalogram ,intracranial pressure and hemodynamics during neurosurgery
Ying HE ; Shuzhen ZHANG ; Xiaoli ZHOU
Chinese Journal of Anesthesiology 1995;0(02):-
Objective To investigate the effect of isoflurane at different concentration on the quantitative electroencephalogram(SEF and BIS) , intracranial pressure(ICP) and hemodynamics during neurosurgery Methods Thirty ASA grade Ⅰ Ⅱ patients with saddle tumor ,scheduled for selective operation, were randomly divided into three groups after induction with fentanyl propofol vecuronium and intubation Anesthesia was maintained with inhalation of 0 5,1 0 or 1 5 MAC of isoflurane in each group respectively MAP,HR,ICP,SEF and BIS were recorded before induction,reaching the designed MAC, at incision ,sawing bones and opening dura Results SEF and BIS decreased significantly with increases in concentration of isoflurane MAP decreased markedly at1 5 MAC compared with that at 0 5 MAC (P
6.Strengthen the Humanities Education for Hospital Political Affairs Staff to Enhance Their Qualification——An Investigation of Humanities Qualification of Hospital Political Affairs Staff in Yancheng Manicipal Hospitals
Shuzhen LIU ; Rongbin LIU ; Yimin ZHOU
Chinese Medical Ethics 1995;0(03):-
A sample investigation is conducted among 109 political affairs staff from different scales of hospitals in Yancheng city.By analyzing the investigation data,this paper points out there is a lack of humanities qualification among hospital political affairs staff.Some countermeasures are also come up with as follows.The enhancement of humanities knowledge should be the first step to improve qualification of political affairs staff.Political affairs staff should take a positive role in adapting to the challenges of information economics.The political affairs work should be initiated with humanities culture in order to keep pace with social progress.The mutual improvement in humanities education and political affairs work lies a solid foundation for the construction of a harmonious physician-patient relationship.
7.Surgical treatment of giant intracranial meningiomas and prevention of complications
Wenying LUO ; Xiaofeng WANG ; Shuzhen YANG ; Yongchun ZHOU ; Rongjun ZHANG
Chinese Journal of Postgraduates of Medicine 2014;37(2):31-33
Objective To summarize the experience of surgical techniques and prevention of postoperative complications of giant intracranial meningiomas.Methods The clinical data of 32 patients with giant intracranial meningiomas were analyzed retrospectively.The cause of operative complications was analyzed and the experience was summarized.Results The meningiomas Simpson grade Ⅰ resection was 16 is.cases,grade Ⅱ resection was 9 cases,grade Ⅲ resection was 5 cases,grade Ⅳ resection was 2 cases.The postoperative complications included anemia was 14 cases,intracranial hemorrhage was 2 cases,severe cerebral edema was 4 cases,epilepsy was 3 cases,cerebral infarction was 2 cases,and recovered well after treatment.Conclusion Good surgical technique,advanced prevention of surgical complications,early diagnosis and treatment can significantly improve the prognosis.
8.Effect of additives on the microstructure of machinable bioglass-ceramic
Xinhua ZHOU ; Ying CHU ; Anmin CHEN ; Shuzhen SUN
Chinese Journal of Tissue Engineering Research 2007;11(22):4443-4446
BACKGROUND:Machinable bioglass-ceramics became a new inorganic biomaterial; moreover, strength, toughness and machinability are significantly studied.OBJECTIVE: To observe the effect of ZnO, Fe2O3 and ZrO2 additives on the microstructure and properties of machinable bioglass-ceramic in K2O-MgO-CaO-SiO2-P2O5-F system.DESIGN: Observational contrast study.SETTING: Department of Orthopaedics, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology.MATERIALS: The experiment was carried out in the Laboratory of Materials, Wuhan University of Technology from October 2003 to April 2004. K2O-MgO-CaO-SiO2-P2Os-F system, ZnO, Fe2O3 and ZrO2 additives, D/Max-ⅢA X-ray diffractometer (Japan), JSM-5610LV scanning electron microscope (SEM), HVS-1000 microhardnessmeter and 3257-35 magnetic testing device (Japan) were used in this study.METHODS: In the glass-ceramic of K2O-MgO-CaO-SiO2-P2O5-F system, three kinds of additives ZnO, ZnO-Fe2O3 and ZnO-Fe2O3-ZrO2 were added respectively. These three kinds of ceramics were prepared by being melted at 1 400 ℃ for 1 hour. After fire, crystal temperature was set based on differential thermal analysis curve. ① Physical properties: Microhardness was determined with microhardnessmeter (HVS-1000). The flexural strength and fracture toughness were established measured with ceramic mechanical test system (MTS) method and single edge notched beam (SENB) method, respectively. Saturation magnetic moment and Curie temperature were determined with 3257-35 magnetism test machine made in Japan. Holing method was used to measure machinability. ② Test of crystalline phase and microstructure: Crystalline phase analysis was carried out with X-ray diffraction (XRD: D/Max-ⅢA) and microstructure analysis were conducted on an etched fracture surface using SEM (JSM-5610LV,Japan). MAIN OUTCOME MEASURES: Effects of ZnO, Fe2O3 and ZrO2 additives on physical properties, mineral composition and crystalline phase.RESULTS: ① The addition of ZnO to the glass-ceramic in K2O-MgO-CaO-SiO2-P2O5-F system was beneficial to crystal growth, increasing aspect ratio of crystal, decreasing microhardness and improving toughness and machinability. ② The addition of ZnO-Fe2O3 to the glass-ceramic in K2O-MgO-CaO-SiO2-P2O5-F system can form minority Mg-Zn ferrite with magnetism. The main crystalline phase present in the glass- ceramic was diopside with small size and hardness was improved, which led to worse machinability. ③ Because of the addition of ZnO-Fe2O3-ZrO2, magnesia fluormica and fluorapatite became the main crystalline phases, and the minor phases including Mg-Zn ferrite, t-ZrO2 and m-ZrO2, etc.also presented in the glass-ceramic. This material possessed high strength and toughness, good machinability and magnetism, which could stimulate formation of new bone, and was good substitute of bone restorations. Bioassay and in vitro test indicated that the glass-ceramic in K2O-MgO-CaO-SiO2-P2O5-F system was bioactive and biocompatible. CONCLUSION: ZnO, Fe2O3 and ZrO2 additives play a significant role in changing crystalline structure, enhancing strength,toughness and machinability of machinable bioglass-ceramic and generating magnetism.
9.Clinical significance and influence of Yangyin Yiqi mixture on levels of interferon -γand interleukine -10 in serum and saliva of oral lichen planus patients
Shuzhen ZHOU ; Yunyun GAO ; Jing XIE ; Mengfei GAO
Chinese Journal of Primary Medicine and Pharmacy 2016;23(22):3366-3369
Objective To evaluate the clinical efficacy of Yangyin Yiqi mixture and western medicine in the treatment of oral lichen planus(OLP)and its effect on the levels of interferon -γ(IFN -γ)and interleukine -10 (IL -10)in serum and saliva.Methods Sixty patients with OLP were randomly divided into control group(n =30) and treatment group(n =30).The control group was treated with triamcinolone acetonide and lidocaine,local injec-tion.The treatment group was treated with Yangyin Yiqi mixture on the basis of the control group.The treatment lasted two months.After treatment,the clinical efficacy,objective indicators score,levels of IFN -γand IL -10 in serum and saliva,adverse reactions were compared between the two groups.Results The overall response rate of the treatment group (86.67%)was significantly higher than that of the control group (63.33%)(χ2 =11.64,P <0.01).After treatment,the two groups'objective index score significantly reduced(t =8.52,12.51,all P <0.01),and the treat-ment group's objective indicators rating was significantly lower than the control group (t =4.38,P <0.05).After treatment,the levels of IFN -γin serum and saliva were (25.39 ±1.29)pg/mL and (12.76 ±1.28)pg/mL,which were significantly increased in the treatment group (t =10.35,8.15,all P <0.01),so did the control group (P <0.05).And the levels of IL -10 in serum and saliva were (27.54 ±1.82)pg/mL and (9.92 ±0.86)pg/mL,and the levels were significantly decreased in the two groups after treatment (t =8.76,9.39,all P <0.01,t =4.65,4.94,all P <0.05).And levels of IFN -γin serum and saliva of the treatment group were significantly higher than those of the control group (t =4.68,4.32,all P <0.05),and levels of IL -10 in serum and saliva of the treatment group were significantly lower than those of the control group (t =5.41,5.25,all P <0.05).During treatment,there were no sig-nificant adverse reactions.Conclusion Yangyin Yiqi mixture combined with western medicine has definitive clinical efficacy in the treatment of OLP.It can significantly increase the level of IFN -γand reduce the level of IL -10 in serum and saliva in patients,so provide theory value for treatment of OLP.
10.Relationship between neuromuscular block induced by cisatracurium for tracheal intubation during anesthesia induction and types of myasthenia gravis
Ruifang JIA ; Xiaoyan MENG ; Shuzhen ZHOU ; Mingzhang ZUO
Chinese Journal of Anesthesiology 2017;37(4):454-457
Objective To determine the relationship between neuronuscular block induced by cisatracurium for tracheal intubation during anesthesia induction and types of myasthenia gravis (MG).Methods Sixty-five patients of both sexes with MG,aged 20-75 yr,weighing 53-92 kg,with body height of 155-185 cm,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,undergoing elective videoassisted thoracoscopic thymectomy,were enrolled in the study.Among the 65 patients,there were 8 patients with ocular MG (type Ⅰ),19 patients with mild generalized MG (type]Ⅱ a),33 patients with subacute generalized MG (type Ⅱ b),2 patients with acute MG (type Ⅲ) and 3 patients with late severe MG (type Ⅳ).Neuromuscular monitoring was initiated when the patients lost consciousness after induction of anesthesia.Cisatracurium was administrated with the initial dose of 0.05 mg/kg,and if T1 depression was less than 95% within 6 min,cisatracurium 0.015 mg/kg was intravenously injected until T1 depression was more than 95%.The patients were then tracheally intubated.The amount of cisatracurium consumed for intubation,onset time (from the beginning of cisatracurium injection to T1 depression >95%) and recovery time (recovery of T4/T1 to 25% of control height) of neuromuscular block were recorded.T1 depression > 95% within 6 min after administration of 1-fold ED95 cistracuriun was defined as sensitivity to muscle relaxants.The requirement for cistracurium > 1-fold ED95 when T1 depression > 95% was defined as insensitivity to muscle relaxants.The proportion of sensitivity/insensitivity was calculated.Results There was no significant difference in the amount of cisatracurium consumed for intubation and onset time and recovery time of neuromuscular block between patients with type Ⅰ and those with type Ⅱ a (P>0.05).Compared with patients with type Ⅰ and type]Ⅱ a,the amount of cisatracurium consumed for intubation was significantly decreased,the proportion of sensitivity/insensitivity was increased,the onset time was shortened,and the recovery time was prolonged in patients with type Ⅱ b (P<0.05).Conclusion With the severity of MG,the consumption of cisatracurium is gradually decreased when used for tracheal intubation during anesthesia induction,and the sensitivity is gradually increased in the patients with MG.