1.Quality Standard for Infantile Bronchitis Traditional Chinese Medicine Lotion
Yanning WANG ; Cuihong ZHAO ; Shuyue WU
China Pharmacist 2017;20(2):368-371
Objective:To establish the quality standard for infantile bronchitis traditional Chinese medicine lotion. Methods:TLC was used for the qualitative identification of Ephedra herba, Paeonia lactiflora Pall. , Poria cocos, Fructus aurantii and Epimedium brev-icornu Maxim. . HPLC was used for the content determination of ephedrine hydrochloride, pseudoephedrine hydrochloride and paeoni-florin. The chromatography conditions for ephedrine hydrochloride and pseudoephedrine hydrochloride were as follows: an AElichrom Pdar-Phenyl Polyphenyl ether-bonded phenyl-bonded silica column (250 mm × 4. 6 mm, 5μm) was used, the mobile phase was aceto-nitrile-0. 2% phosphoric acid solution (1 :99), the flow rate was 1. 0ml·min-1, the detection wavelength was 210 nm, the column temperature was 30℃ and the injection volume was 10 μl. The chromatography conditions for paeoniflorin were as follows:an Inertsil ODS-3 C18 column (250 mm × 4. 6 mm, 5 μm) was used, the mobile phase was acetonitrile-0. 1% phosphoric acid solution (15:85), the flow rate was 1. 0 ml·min-1, the detection wavelength was 230 nm, the column temperature was 30℃ and the injection vol-ume was 10 μl. Results:The TLC results of Ephedra herba, Paeonia lactiflora Pall. , Poria cocos, Fructus aurantii and Epimedium brevicornu Maxim. showed clear spots with good resolution. Ephedrine hydrochloride, pseudoephedrine hydrochloride and paeoniflorin had a good linear relationship within the range of 10.11-101.10 μg·ml-1(r=0.9996), 10.08-100.80 μg·ml-1(r=0.9991) and 20.50-102.5 μg·ml-1(r =0.9996), respectively. The average recovery was 98.80% (RSD =1.87%, n =6), 98.77%(RSD=1. 72%, n=6) and 99. 57% (RSD=1. 56%, n=6), respectively. Conclusion: The established quality standard can be used for the quality control of infantile bronchitis traditional Chinese medicine lotion.
2.A clinical study of 35 cases of Silver-Russell syndrome
Shuyue HUANG ; Chunxiu GONG ; Yang ZHAO ; Di WU ; Bingyan CAO
Chinese Journal of Endocrinology and Metabolism 2014;30(2):119-122
Objective To analyze the clinical features of 35 patients with Silver-Russell syndrome (SRS) in Beijing Children's Hospital in recent 6 years,and to recognize the clinical manifestations and improve the diagnosis of the disease.Methods The diagnostic criteria of SRS were studied retrospectively,the differences among 3 different diagnostic criteria were compared.Results Thirty-five SRS patients were diagnosed by means of 3 criteria,over a period from 2006 to 2012.There were 23 males and 12 females,with age range 0.08 ~ 12.15 yr.77 % of cases met the three criteria,97% met two of the three criteria.There were dwarfism in 33 cases (94.2%),genital abnormalities in 1 case (2.9%),and asymmetry of limbs in 1 case (2.9%).The clinical characteristics with the frequencies accounting for over 80% included short stature (average height-3.61 SDS),leanness (body mass index <-2.11SDS),bone dysmorphism including triangular face,irregular teeth,asymmetry of limbs,clinodactyly of fifth finger,and bone age obviously lagged behind.60% of the cases showed bone age lagging behind more than 1 year.Height lagging behind was more obviously then bone age.Conclusions The diagnosis of SRS is mainly based on Clinical manifestation,laboratory and biochemical examinations are of no avail.There is a high coincidence with the 3 different diagnostic criteria.Clinical features in more than 80% patients with SRS are short stature,craniofacial triangular dysmorphism,irregular teeth,limbs asymmetry and fifth finger clinodactyly,and mild lagging behind of bone age.
3.Expanding Strategy of Medical Engineering Department in Hospital
Shuyue ZHAI ; Zhengyu WU ; Pingan QU ; Hao WANG
Chinese Medical Equipment Journal 1989;0(03):-
With the expanding development of engineering of medical service,medical engineering department should adapt to hospital development.Expanding principle and the goal of medical engineering department are expounded.The fundamental content of the expanding strategy includes mechanism of purchasing and purveying,construction and management of both equipment maintenance and medical metrological organization,training to faculty of specialized subject,orientation of scientific research,etc.
4.Lowering Inventory Cost of Chinese Patent Drugs by Means of Zero-Inventory-Ordering System
Biao CHEN ; Shuyue WU ; Yanning WANG ; Hui ZHONG
China Pharmacy 2005;0(22):-
OBJECTIVE:To explore an effective,economical drug purchasing mode for hospital drug warehouse.METHODS:The inventory costs and stock turnover rates for the zero-inventory-ordering system and fixed-interval-ordering system once applied in the Chinese patent drug stockroom in our hospital were analyzed using the analytical method of stock turnover rate.RESULTS:The average inventory costs of 2 policies were 155 600 yuan and 103 800 yuan,respectively,and their average stock turnover rates were 199.23% and 301.16%,respectively.CONCLUSION:The zero-inventory-ordering system is more conducive to the reduction of inventory cost of stock drugs.
5.Quality control and administration of PET-CT
Jun YANG ; Jianwei WU ; Shuyue AI ; Wei HUANG
Chinese Medical Equipment Journal 2004;0(09):-
The purpose of quality control is to form a standard,scientific,and unified control system for PET-CT.The improvement of regulations is the base.The training of technicians is the key.The establishment of radiological protection rules is the assurance.So it is an important link to improve the quality control of PET-CT for better sensitivity and accuracy of PET-CT.
6.Analysis of Clinical Application of Xueshuantong for Injection(Lyophilized)in Our Hospital
Yanning WANG ; Huiling ZHANG ; Qiaoqin WANG ; Shuyue WU
China Pharmacy 2017;28(9):1193-1196
OBJECTIVE:To provide reference for promoting clinical rational application of Xueshuantong for injection(lyophi-lized). METHODS:By hospital centralized monitoring method,all medical records were retrieved from Hospital Information Sys-tem of our hospital,who received Xushuantong for injection(lyophilized)from Aug. 7 to Oct. 6 in 2015;general information of patients'drug information,drug utilization and the occurrence of ADR were traced and recorded by clinical pharmacists to evaluate the rationality of clinical utilization of Xushuantong for injection(lyophilized). RESULTS:Totally of 1014 medical records were included in the study. Xueshuantong for injection(lyophilized)was mainly used for fracture,cerebral infarction,coronary disease, cataract and other disease. 22 clinical departments as orthopedics department,neurology department,cardiology department and ophthalmology department were involved,accounting for 56.41% of total. For the patients receiving Xushuantong for injection(ly-ophilized),the average age was 63.12 years,the average course was 11 days and dose was 100-500 mg/time. They were given medicine intravenously once a day,and 0.9% Sodium chloride injection was used as solvent (93.29%). There were 10 kinds of drugs for drug combination averagely. The incidence of ADR was 5.92‰,and all ADR resulted from same batch of drugs (No. 15040211);ADR mainly manifested as erythra,erythema,pruritus,chills,etc. In terms of irrational drug use,the incidence of overlong treatment course was 17.85%;that of inadequate solvent dose was 13.71%;that of fast dripping rate was 7.59%;that of unsuitable solvent selection was 0.69%;that of drug use with no indication was 0.39%. CONCLUSIONS:Xueshuantong for injec-tion(lyophilized)is widely used in middle-aged and elderly in the clinic. There are many varieties and irrational drug use. The oc-currence of ADR is properly related to age,treatment course,solvent,dripping speed,product quality and other factors. Clinical pharmacists are required to monitor drug use,promote the rationality of drug use and reduce the occurrence of ADR.
7.Skin Susceptibility Test of Jaundice-abating Chinese Herbal Lotion for External Use
Shisun HUANG ; Yanning WANG ; Guie GAO ; Shuyue WU
China Pharmacy 2007;0(30):-
OBJECTIVE:To study the safety of Jaundice-abating Chinese Herbal Lotion for External use through animal skin susceptibility test so as to provide references for its clinical application.METHODS:Skin and systemic susceptibility tests were conducted in accordance with the pertinent standards issued by our country.RESULTS:Neither skin allergic reaction nor systemic allergic reactions were noted for jaundice-abating Chinese Herbal Lotion for external use.CONCLUSION:Jaundice-abating Chinese Herbal Lotion for external use meets the clinical requirements in the skin susceptibility test.This drug was proved to be safe in the local or systemic application,and it can be used in the clinic through systemic tub bath.
8.Prevention and treatment of oral lesion in AIDS by Chinese herb gargle
Yonying HE ; Peiqiu ZHENG ; Fuqiu DENG ; Feili LIANG ; Yanping CHEN ; Yirong WEI ; Shuyue WU
Chinese Journal of Practical Nursing 2010;26(16):58-60
Objective To study the effects of self-made Chinese sherbal gargle on AIDS related oral lesion.Methods 353 hospitalized AIDS patients from June 2007 to December 2009 were divided randomly into the experimental group(179 patients)and the control group(174 patients).ALL the patients were treated with systemic anti-viral therapy while the experimental group was mouthwashed by self-made herbal gargle and the control group with normal saline solution.The incidence of new oral lesion and the changes of the originM lesion were observed.Results The incidence of new oral lesion in the experimental group was obviously lower than that of the control group.The cure rate and effective rate of original oral lesion were much higher than the control group.Conclusions Self-made herbal gargle shows good effect in preventing and treating the AIDS related oral lesion.
9.Influenc of electroacupuncture on urinary retention after abdominal operation
Yanying HE ; Peiqiu ZHENG ; Shaofang YAN ; Guihua DENG ; Yanping CHEN ; Shuyue WU
Chinese Journal of Practical Nursing 2010;26(13):7-9
Objective To investigate the effect of prevention and treatment of urinary retention for patients after abdominal surgery using electroacupuncture unit model 6805.Methods 180 cases of ab-dominal surgery patients were randomly divided into three groups, the treatment group(64 patients)were treated with electroacupuneture at the points of sanyinjiao, zhongji, pangguangyu, the control group 1(57patients)Was treated with moxibustion and foment were used in the control group 2(259 patients).The incidence rate of urinary retention Was compared between the three groups. Results The rate of spontaneously emiction was 56.25%in 30 minutes and 35.94%in 40 minutes in the treatment group, the results in the control group 1 and 2 were 22.81% and 15.79%,23.73% and 13.56% respectively. There were significant differences between three groups. Conclusions Electroacupuncture Can effectively prevent and treat urinary retention after abdominal operation.
10.CT measured parameters of upper airway in OSAHS patients
Maogu LU ; Dongsheng MIAO ; Wei LUO ; Shuyue AI ; Ying ZHAO ; Jianwei WU
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(07):-
OBJECTIVE To explore the value of spiral CT in detecting narrow level of obstructive sleep apnea hypopnea syndrome(OSAHS) through investigating measured parameters of upper airway. METHODS The upper airway levels from the roof of nasopharynx to the inferior border of cricoid cartilage were scanned with spiral CT in 127 OSAHS patients and 52 controls.The coronal and sagittal diameter and the cross sectional areas of palate,uvula,tongue, epiglottis level were measured using image handling workstation.The measured values of each level were divided by the measured values of the cricoid cartilage level,and get relative values.The relative values of the OSAHS patients and controls were compared. RESULTS The relative values of posterior soft palate and uvula region,lingual region and epiglottis regions were statistically different.The difference also existed between genders.The relative values of 46 controls and 17 OSAHS patients were in the normal range. Among 127 OSAHS,the relative values of 110 cases with OSAHS(86.6%) were below the normal range in every region,while in control group,the relative values were found below the normal range in only 6 persons (11.2%).CONCLUSION The relative values of each regions is useful to judge the narrow level of upper airway in OSAHS patients.