ObjectiveTo explore the effect of second-stage revision in treating infection after artificial total hip arthroplasty.MethodsThe clinical data of 11 cases with infection after artificial total hip arthroplasty who got second-stage revision from April 2007 to October 2009 were analyzed retrospectively.All patients were treated with first-stage complete debridement,antibiotic-loaded bone cement prosthesis implantation and second-stage revision after controlling infection.The therapeutic effect was assessed by Harris hip score,laboratory examination and imaging study.ResultsThe average interval of first-stage debridement and second-stage revision was 5.6 (4-11) months.The average time of follow-up was 34 (24-48) months.None of 11 patients had reinfection and complications.Harris hip score before operation [17-43 (30.71±13.52) scores] and during follow-up after operation [72-96 (84.38±12.85) scores] had statistical significance (P＜ 0.05).Six cases had good effect,4 cases were moderate and 1 case was acceptable.The rate of good and moderate effect was 90.91％( 10/1 1 ).ConclusionsSecond-stage revision can reserve the function of hip joint effectively and has high infection eradicating rate.Therefore,it is an effective treatment for postoperative infection of artificial total hip arthroplasty.

To analyze preponderance and prohibition of combined using of tradifional Chinese and western medicine in clinical treatment,hoping to provide referencefor clinical application.

Objective To evaluate the incidence of nasopharyngeal hemorrhage after radiotherapy of nasopharyngeal carcinoma (NPC) in order to adjust adequately the dose of fractionated stereotactic radiosurgery (FSRS). Methods Eighteen NPC patients were treated by FSRS following conventional radiotherapy of D T65～74?Gy. Of them, 5 patients (T 4) with uncontrolled lesions received a boost dose of 24～40?Gy/6～8 f and 13 patients (T 2～3 ) with local recurrence received their second course of treatment with different regimens. Group A: 8 patients received routine radiotherapy 30～40?Gy followed by FSRS 24～30?Gy/6～9 f; Group B: 5 patients received FSRS 40～42?Gy/6～8 f alone. Results The frequency of nasopharyngeal hemorrhage was 3/5 for skull base invasion (T 4 ) lesions. The incidence of morbidity for re radiation after local recurrence of T 2～3 tumor was 1/8 in Group A and 1/5 in Group B.Conclusions The frequency of nasopharyngeal hemorrhage is high in skull base invasion by NPC (T 4).Therefore the dose of FSRS combined with conventional radiotherapy should be limited when re treating local recurrence of NPC.

Objective To establish the measuring methods and relevant influencing factors of liver zone speed index (ZSI) by sound velocity tissue quantification (SVQ) technology in healthy subjects.Methods Liver ZSI were obtained in 49 healthy volunteers using SVQ technique with Zonare Z.one Ultra system.In the first 15 subjects,ZSI were acquired at four positions (superficial and deep parts of right lobe,superficial and deep parts of left lobe).Then the achievement rate in different position of liver was calculated to select the suitable measuring position.The reproducibility was analyzed with intra-group correlation coefficient(ICC).The last 34 healthy subjects received ZSI measurements in the appropriate position only.The reference value of ZSI was calculated using x-± 1.96 s.Results It was stable to measure values of ZSI with SVQ technique.The achievement rate was higher in right lobe with being 1 cm below the liver capsule for the optimal measuring point.There was no significant difference of ZSI value between male and female groups.There was no significant correlation between age and values of ZSI while a significant negative correlation was found between body mass index (BMI) and values of ZSI (r =-0.63,P =0.000).The reference value of body mass index between 18.5-23.9 kg/m2 was 5.67-36.29 m/s.Conclusions ZSI values of liver measured with SVQ technique shows a good stability and may be a new promising method for assessment of liver elasticity quantitatively.

Objective:To establish the quality standard for Shule granules. Methods:By TLC, Angelic asinensis, Panax pseudog-inseng, Fructus liquidam-baris and Leonurus in Shule granules were qualitatively identified;and contents of notoginsenoside R1 and gin-senosides Rg1 in Shule granules were quantitatively determined by HPLC. Results: In the qualitative identification, the clear spots showed good resolution and specificity. The content of notoginsenoside R1 and ginsenosides Rg1 , two main ingredients in Shule gran-ules, was 0. 166 6 and 0. 681 8 mg·g-1 , respectively. Conclusion:The TLC and HPLC-UV determination method is simple, accu-rate and reproducible, and can be used as the quality control method for Shule granules.

From July 1991 to December 1993, 58 patients with Nonsmall cell lung cancer were randomly divided into hypoxyradiotherapy group (32 patients) and radiotherapy alone group (26 patients). Both groups received the sme radiotherapy with radiation dose of D T 65～70 to cancer of lungs. In hypoxia group, 10.5% oxygen gas mixture was inhaled during the therapy per session. The results showed that tumor response rates, immediate survival rates, skin and systemic reactions were similar in both groups. Hemogram was normal in both groups. In the hypoxyradiotherapy group, radioreaction of lungs, esophagus and trachea were milder than radiotherapy alone group (P

Objective To evaluate the value of three-dimensional surface shaded display (SSD) and volume rendering technique(VRT) in diagnosis of scapular injury. Methods Twenty patients of scapular fractures, who were 15 males and 5 males with an average age of 34 years, were examined with SIEMENS PLUS 4 helical CT. Images were reconstructed in workstation with three-dimensional SSD and VRT, and then analyzed and compared with X-ray and 2D CT images. The regions of interesting consisted of acromion, coracoid process, glenoid cavity, supraspinous fossa, scapular spine, infraspinous fossa, lateral margin, medial margin and inferior angle of scapula. All of imagings were evaluated by two experienced radiologists with double blind method. Results 2D CT findings were clinically or operatively confirmed, and also taken as an evaluative standard to analyze the diagnostic rates of the X-ray, SSD and VRT in this study. The positive rates of diagnosis in plain X-ray and SSD were 94.44% and 97.78%, and the false negative rates was 17.65% and 7.84% respectively; the false positive rate of diagnosis of plain X-ray was 0.76%; the positive rate of diagnosis of VRT was 100%. The difference between plain X-ray, 2D CT, SSD and VRT was not statistically significant for scapular fractures, but the quality of imaging to display the fracture details of 3D CT was the best, while 3D CT might obtain the most objective view of scapular fractures. Eight cases of scapular fractures were examined again post-operatively, the reconstructed images of 3D CT displayed the structure of scapular fractures clearly. VRT could show the contour of scapula and position of the internal fixation, as well as the effect of reduction after operation and the healing status of scapular fractures. Conclusion SSD and VRT of spiral CT are effective methods in diagnosing scapular injury. The images of SSD and VRT of spiral CT may provide exact guidance to preoperative protocol and internal fixation. For complicated scapular fractures, these two techniques could be regarded as imaging techniques of choice. Furthermore, VRT provides more important information to apply the internal fixation devices and assess the result of surgical reduction.

Objective To evaluate the clinical significance of measurement of urinary leukotrience E4(LTE4) in patients with asthma.Methods Urinary leukotriene E4 in 28 patients with asthma who experienced acute attack period and asymptomatic period and 18 controls was measured by ACETM competitive enzyme immunoassay and expressed as pg/mg creatinine.In addition,forced expiratory volume in one second was investigated in the patient in acute attack period.Results Urinary LTE4 in acute attack period was significantly higher than that in asymptomatic period(P

OBJECTIVETo investigate whether the genistein can increase the radiosensitizing effect on laryngeal squamous carcinoma Hep-2 cells.METHODS Hep-2 cells were treated with genistein, radiation, and genistein plus radiation respectively. DMSO was used as the control group. EdU assay was performed to assess the short-term effect of genistein and (or) radiation on the proliferation of Hep-2 cells. Clonegenic assay was used to detect the survival rate of Hep-2 cells after treatment with radiation doses of 0, 2, 4, 6, 8 Gy and radiation combined with genistein. The data was fitted into the classic single-hit multi-target mathematical model to analyze the long-term effect on cell proliferation death of Hep-2 cells.RESULTSIt was observed that radiation combined with genistein could significantly inhibit the proliferation of Hep-2 cells. And the SER of 10μmol/L genistein was 1.412.CONCLUTIONGenistein can inhibit the proliferation of Hep-2 cells by DNA synthesis inhibition, and can be an adjunct agent of radiotherapy.

Objective To explore the Caprini risk assessment model for the application of the prevention of VTE in clinical nursing. Methods With a cross:sectional survey research, 6 624 patients were interviewed of a hospital from March to June in 2015.The Caprini risk assessment model was used to screen patients with VTE risk assessment. Results Patients have VTE risk in 6 229 cases, accounting for 94.04%. The patients of low risk, moderate risk, high risk, and super high-risk was 1 889 cases, 1 507 cases, 1 930 cases, 903 cases, accounted for 28.52%, 22.75%, 29.14%and 13.64%respectively. Surgical patients with VTE risk, low risk, moderate, high risk and super high-risk rate was 5.15% (79/1 533), 15.72%(241/1 533), 28.77%(441/1 533), 30.59%(469/1 533), 19.77%(303/1 533), the no-surgery group were 6.21% (316/5 091), 32.37% (1 648/5 091), 20.94% (1 066/5 091), 28.68% (1 461/5 091), 11.79%(600/5 091), two groups compare was statistically significant (χ2= 53.46, P = 0.000); High-risk ratio of trauma surgery,thoracic surgery, neurosurgery, orthopedics, mammary gland and thyroid surgery were63.2%、62.9%、61.5%、58.3%、55.8%; High-risk ratio of oncology medical, respiratory medical, neurology medical, cardiology medical were 92.0% , 68.2% , 55.9% and 64.4% . Conclusions Hospitalized patients have high risk of VTE, it is suggested that include VTE in nursing quality evaluation standard, establish an effective system of VTE risk management. Caprini risk assessment model has been clear about the VTE patients should be special attention, and has been great significance to early screening and prevention of VTE.