People-oriented is the fundamental value of Chinese medical ethics.It is the most important ideological foundation and the most prominent features of the humanities of traditional Chinese medical ethics for its content of philosophy,humanity and sociology.A series of medical ethics incident alerts us that if we violate the scientific concept of "people-oriented" and neglect the requirements of medical ethics and professional ethics training,the development of medicine will lose its orientation,and even depart from the fundamental tenet of people-oriented.

BACKGROUND: Human body is an irregular geometrical one, so it is very difficult to measure its volume.OBJECTIVE: To establish a multiple regressive equation by taking body height and body mass as the independent variables and body volume as the dependent variable, and select optimally the body volume calculative model of male college students.DESIGN: A single-sample univariate analysis.PARTICIPANTS: Twenty-four male students aged 18-22 years were selected from Zhejiang Gongshang University between January 2003 and October 2004.METHODS: The body height, body mass and body volume of the male students were measured. The indexes of body height and body mass were measured with the nationally-recognized fitness test instrument, and the indexes of body volume were measured with a self-made iron container with a diameter of 0.95 m and height of 1.20 m. There was a mark scale for height in the container, water was infused to a fixed height, then the student slowly immersed himself into the water completely and the height difference was recorded. Body volume (m3)=(0.95÷2)2×3.141 59×height difference. The measured data were statistically calculated. A regression equation in two unknowns was established by taking body height and body mass as the independent variables and body volume as the dependent variable with the systematic software for statistical treatment of physical education scientific research data, and the optimal selection of the regression equation was completed.MAIN OUTCOME MEASURES: The measured data of body height,body mass and body volume and the calculative results of the regression equations were observed.RESULTS: ① A regression equation in two unknowns for calculating body volume was established: (^)y=0.006 16 +0.000 022 ×body height +0.000 756×body mass. ② A regression equation in one unknown for bodyvolume and its optimal selection: The linear equation was (^)y=0.000 8×body mass+0.009 2, the logarithm equation was (^)y=0.050 8 Ln(body mass)-0.152 4, the power equation was (^)y=0.001 8×body mass 0.840 9, the exponent equation was (^)y=0.025 8×e0.012 6x, and the multiple correlation coefficient R2=0.992 1-0.997 3, all were close to 1, indicating that the body volume predicted by models was highly correlated with the actual one [r＞r0.001(24-2) , P ＜ 0.001]. The predicted values of the 4 models had no differ-ence from the actual one. ③ Linear equation had the best simplicity in measurement and calculation in the 5 regression equations. ④ The indexes of physical quality, which were highly correlated with body volume,were body shape, physical function and physical quality.CONCLUSION: The index of body volume is one of the important indexes, which cannot be neglected in the study of physical quality. Analyzing from the simplicity of measurement and calculation and the linear goodness-of-fit of equation, the regression equation in one unknown is the best.

Objective To translate the English version of the Medication Adherence Self-efficacy Scale (MASES) into Chinese and to test the reliability and validity of the Chinese version of MASES in patients with hypertension.Methods Totally 285 patients with hypertension were recruited and were investigated by the Chinese version of MASES.The results underwent analysis for reliability and validity.Results The retest reliability of MASES was 0.843.The Cronbach α of the Chinese version of MASES was 0.876.The Cronbach α of the four dimensions ranged from 0.794 to 0.905.The average content vality index (CVI) of the scale was 0.946.Factor analysis got four factors,which explained 68.683％ of the total variance.The factor loading of each item on its common factor was ＞0.4.Conclusions The Chinese version of MASES has been proved to be reliable and valid.It can be used as a valid tool for the measurement of the patient compliance in patients with hypertension.

Objective To translate the English version of the Oncology Patients' Perceptions of the Quality of Nursing Care Scale (OPPQNCS) into Chinese and to test the reliability and validity of the Chinese version of OPPQNCS in oncology patients.Methods The English version of OPPQNCS was translated by Brislin translation mode.Totally 320 oncology patients were recruited and were investigated by the Chinese version of OPPQNCS.Results The internal consistency coefficient of the Chinese version of OPPQNCS was more than 0.70,ranged from 0.804 to 0.964;the test-retest was 0.826.The content validity index(CVI) was 0.845-1.000,the average CVI was 0.925.Factor analysis got four factors,which explained 78.548％ of the total variance.And every objective factor loading were greater than 0.4.Conclusions The Chinese version of OPPQNCS has been proved to be reliable and valid.It can be used as a valid tool for the oncology patients to measure their perceptions of the quality of nursing care they got.

Owning its unique and complete ideological system,Pre-Qin Confucian Bioethics includes the life value of "respect life and cherish materials",the life &death value of "cheer for life and grieve over death",and the health preservation value of "cultivate oneself to make progress".Pre-Qin Confucian Bioethics clarifies the very nature of life and utmost pursuit,and also sets up a norm of ethical options and fundamental approach to pursuing self life quality and health in a practical angle.Therefore,it is of great revealing significance for the formation of a scientific bioethical value.

Objective To explore the effect of flow yoga on balance ability and fear of falling of community patients with stroke.Methods Divided 92 community patients with stroke into the intervention group (46 cases) and the control group (46 cases) randomly,routine community nursing cares were used in the control group,while the flow yoga were used in the intervention group in addition.The berg balance scale,single direct question of fear of falling and modified falls efficacy scale were used to evaluate balance ability and fear of falling after the intervention between the two groups.Results The patients' balance ability was (48.28±10.64) in the intervention group,which was significant higher than that of in the control group (32.04±11.42),t=6.316,P＜0.05.The fall efficacy in the intervention group was (132.03±27.38),which was significant higher than that of in the control group (108.74±25.68),t=8.256,P＜0.05.The rate of fear falling in the intervention group was 26.09％(12/46),which was significant lower than that of in the control group (32.16T％,15/46),x2=6.545,P＜0.05.Conclusion Flow yoga can improve stroke patients' balance ability and reduce fear of falling.

To investigate the temporal variation of cell-mediated immunity in injured tissue of maxillofacial firearm trauma. Cells expressing messenger RNA(mRNA) for IL-2 were demonstrated by dot blotting and in situ hybrization in injured tissue of maxillofacial trauma inflicted by bullet, in conjunction with immunohistochemistry for IL-2 in normal and postinjury conditions. It was found that, apart from a transient eleratim in level within 24h post injury, both IL-2 production and IL-2 mRNA expression were consistently suppressed in cells at the site of the wound compared with the normal. The changes in the tissues of indirect injury by the projectile were significant. These results indicate that the cell-mediated immunity was suppressed in maxillofacial firearm trauma and the principal cellular abnormalities that resulted in altered T cell activation and IL-2 production postinjury was downregulation of mRNA before IL-2 gene transcription. It also suggested that the indirect injury by projectile contribute mainly to the depression of cell-mediated immunity.

Objective To translate the English version of the Client-Centred Care Questionnaire (CCCQ) into Chinese and to test the reliability and validity of the Chinese version of CCCQ.Methods The English version of CCCQ was translated into Chinese by the method of double translation-translation.Totally 320 chronic patients were recruited and they were investigated by the Chinese version of CCCQ.Results The Cronbach coefficient of the Chinese version of CCCQ was 0.925,P＜0.01.The retest reliability was 0.807,P＜0.01.The split-half reliability with r=0.883,P＜0.01.The content validity index (CVI) was 0.956,and every purpose CVI values were above 0.8.Factor analysis got one factor,which explained 52.549％ of the total variance,and each objective factor loading was above 0.4.Conclusions The Chinese version of CCCQ has been proved to be reliable and valid.It can be used as a valid tool for the chronic patients to measure their perceptions of the quality of nursing care.

BACKGROUND:Stem cel transplantation, in recent years, has become a preferred treatment for premature ovarian failure. Umbilical cord blood mononuclear cel s containing a large number of mesenchymal stem cel s, immature stem/progenitor cel s, and endothelial progenitor cel s can be used as an important source of stem cel transplantation.
OBJECTIVE:To study the therapeutic efficacy of human umbilical cord blood mononuclear cel transplantation on radioactive premature ovarian failure in nude mice.
METHODS:120 female BALB/C nude mice were randomly divided into four groups:blank control group without any intervention;model group, intravenous transplantation group, and in situ transplantation group exposed to 60Coγrays, 0.5 Gry per day, for 30 days. After 30 days, premature ovarian failure models were made in the latter three groups. Then, nude mice in the latter three groups were given bilateral ovary injection of 10 μL DMEM, tail vein injection of 10 μL human umbilical cord blood mononuclear cel s (1×1013/L), and bilateral ovary injection of 10 μL human umbilical cord blood mononuclear cel s (1×1013/L), respectively. Thirty days after cel transplantation, serum levels of estradiol, fol icle hormone, luteinizing hormone, inhibin B and vascular endothelial growth factor were detected, cel apoptosis in the ovary tissue and cel survival were observed pathological y.
RESULTS AND CONCLUSION:After modeling, the serum levels of estradiol, inhibin B and vascular endothelial growth factor were significantly reduced (P<0.01), while fol icle hormone and luteinizing hormone levels increased (P<0.01). After transplantation, these indexes were al improved in the in situ transplantation group (P<0.01), and reduced fol icle hormone and luteinizing hormone levels were visible in the intravenous transplantation group (P<0.05, P<0.01). Compared with the model group, in situ transplantation and intravenous injection of human umbilical cord blood mononuclear cel s could effectively reduce cel apoptosis in the ovary tissue (P<0.05), and transplanted cel s were able to survive in the ovary of nude mice. Al these findings show human umbilical cord blood mononuclear cel transplantation do have curative effects on premature ovarian failure in nude mice through the inhibition of apoptosis and the regulation of hormone secretion.

Based on previous research on the knowledge network,the paper summarizes the relevant research on the concept evolution,structure,model,evaluation index and practical application of the knowledge network based on the literature carrier,and provides reference for knowledge management and scientific innovation management.