1.Comparative study between the characteristics of facial nerve jnjury resulted from gun-shot and that from blast
Yanliang WANG ; Delin LEI ; Shuxia ZHOU ; Zhenxi BAI ; Zhaoling WANG
Journal of Practical Stomatology 1995;0(04):-
Objective: To study the difference between the facial nerve injury by gun-shot and that by blast. Methods: 40 adult dogs were divided into 2 groups, with 20 dogs in each. In the blast group, the impact wave was simulated by detonator blast in the distance of 10 cm over the dog's masseter. At the same time,a steel ball was projected to the dog's face by a rifle to imitate segments in blast. In the gun-shot group, only the steel ball was used. Then the facial nerve was taken at the time of immediateness, 6 hours, 1 day, 3 days and 7 days following the injury for HE or immunocytochemical staining. And the facial nerve conduction velocity was examined 6 hours, 3 days and 7 days after injury.Results: The facial nerve edema was found in both groups just after injury. There was scattering hemorrhage and little hematoma below the spineurium in the gun-shot wound, as well as the diffusing bleeding and larger hematoma in blast wound. In the blast group, the severe edema could be found by light microscope in the whole extracranial facial nerve. Axonal fragments, infiltrating imflammatory cells and few neurofilament protein NF positive axons were observed. In the gun-shot group, only scattering damage was found within 2 cm from the wound track.Conclusion: The facial nerve injury by gun-shot bacomes less severe with the increase of distance from the wound track, but the blast injury is wider and more severe.
2.Effective dose and safety of adenosine triphosphate in inducing dual atrioventricular nodal pathways phenomenon
Side LU ; Shuxia BAI ; Dongsheng LI ; Hongkao ZHANG ; Jijun LIU ; Lei WANG
Chinese Journal of Postgraduates of Medicine 2010;33(1):30-32
Objective To investigate the effective dose and safety of adenosine triphosphate(ATP) in inducing dual atrioventricular nodal pathways(DAVNP)phenomenon.Methods The ATP(the initial dose was 0.15 mg/kg,incremented 0.10 mg/kg each time)was injected to 40 patients who had slow-fast atrioventricular nodal reentrant tachycardia(AVNRT)through a femoral vein until signs of DAVNP,second-or third-degrec atrioventricular block(AVB)appared.The surface and intracardiac electrocardiogram was recorded consecutively.Results Forty patients of the slow-fast AVNRT had AVB after injecting ATP (16.1±5.8)mg(9-22 mg),29 patients(72.5%,29/40)occurred DAVNP phenomenon,of which 11 (37.9%,11/29)revealed DAVNP phenomenon after injecting ATP 0.15 mg/kg.Seventeen patients had side-effects of dyspnea,dizziness,cough,cardiopalmus and so on,but these side-effects were generally minor,short duration.Forty patients had transient cardiac arrhythmia.Conclusions The incremental low-dose method in inducing DAVNP has higher positive rate.The side-effects of ATP are mostly light and short duration,and can not cause serious consequence.
3.ZJU index and the risk of nonalcoholic fatty liver disease in the Uygur population in the rural area of Xinjiang Uygur Autonomous Region: A cohort study
Xiao CHENG ; Jiajia WANG ; Jing YANG ; Rong BAI ; Shijie ZHANG ; Hongwei ZHANG ; Xiangwei WU ; Rulin MA ; Xianghui ZHANG ; Heng GUO ; Shuxia GUO ; Xinyu PENG
Journal of Clinical Hepatology 2023;39(11):2588-2595
ObjectiveTo investigate the association between ZJU index and the onset of nonalcoholic fatty liver disease (NAFLD) in the Uygur population and the value of ZJU index in predicting the risk of NAFLD. MethodsThe Uighur community of The 51st Regiment of The Third Division of Xinjiang Kashgar Corps was selected as the investigation site, and the Uygur residents who lived in this area and had an age of >18 years were selected as subjects. Follow-up studies were conducted in 2019, 2020, and 2021, and the investigation of outcomes was completed in June to August of 2021. Finally 10 597 subjects were enrolled for analysis. The Kruskal-Wallis H test was used for comparison of continuous variables between groups, and the chi-square test was used for comparison of categorical variables between groups. The subjects were divided into Q1-Q4 groups according to the level of ZJU index. The Kaplan-Meier curve was used to predict the incidence rate of NAFLD, and the Cox regression model was used to analyze the association between ZJU index and the risk of NAFLD; the area under the ROC curve (AUC) was used to evaluate the value of ZJU index in predicting the risk of NAFLD. ResultsDuring the median follow-up time of 4.92 years, the incidence rate of NAFLD was 9.4% (992/10 597) among the study population. After adjustment for multiple factors, there was a significant increase in the risk of NAFLD with the increase in ZJU index, with a hazard ratio of 2.55 (95% confidence interval [CI]: 1.60 — 4.06), 7.32 (95%CI: 4.78 — 11.20), and 21.74 (95%CI: 14.32 — 33.00), respectively (all Ptrend<0.001). The ROC curve showed that ZJU index had a higher value in predicting NAFLD (AUC=0.816), and the male subgroup had a significantly higher predictive accuracy of ZJU index than the female subgroup (AUC: 0.829 vs 0.809). ConclusionZJU index is a predictive factor for the onset of NAFLD in the Uygur population in rural areas of Xinjiang and has a good value in predicting the risk of NAFLD.