1.The comparison of endoscopic and histological findings between antrum and corpus in functional dyspeptic patients
Peng LI ; Shutian ZHANG ; Zhonglin YU
Chinese Journal of Practical Internal Medicine 2001;0(10):-
Objective To compare the differences between antrum and corpus in endoscopic and histological diagnosis in non-ulcer dyspeptic patients.Methods 132 cases from out-patient department who had been ordered to undergo gastroendoscopy for dyspepsia were enrolled in the study.After endoscopy,different signs including redness,erosion,intramural bleeding and rugal atrophy were described.Histological diagnosis was defined according to the classification of chronic inflammation,polymorphonuclear neutrophil activity,glandular atrophy,intestinal metaplasia,helicobacter pylori and dysplasia.The differences between antrum and corpus in endoscopic and histological diagnosis were analyzed.Results Redness and erosion under endoscopy,glandular atrophy and chronic inflammation in histological diagnosis were found more frequently in antrum than in corpus.P values were less than 0.001,0.01,0.001 and equaled to 0.025 respectively.Conclusion In functional dyspeptic patients,there are differences in the endoscopic and histological findings between antrum and corpus.Redness and erosion in endoscopic diagnosis,glandular atrophy and chronic inflammation in histological diagnosis are more common in antrum when compared with that in corpus.
2.Hemocoagulase vs. Epinephrine in Endoscopic Mucosal Resection:Prospective Randomized Controlled Study
Wenyan LI ; Ming JI ; Shutian ZHANG
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To compare the anti-hemorrhage effect and safety of hemocoagulase and epinephrine (1∶10 000) during endoscopic mucosal resection (EMR) or polyps electrocautery. Methods Between April and November 2007,totally 60 patients received EMR or endoscopic piecemeal mucosal resection (EPMR) in our hospital because of local lesions in the esophagus,stomach or colon. The patients were randomly divided into hemocoagulase and epinephrine groups (30 cases in each) before receiving the operation. After the resection,the hemorrhage at the surgical area was measured. During the operation,the blood pressure,heart rate,and adverse effects including palpitation,dizziness,pain,and nausea were recorded. Results Immediate hemorrhage was detected in 1 case of hemocoagulase group (1/30,3%),and 6 cases of epinephrine group (6/30,20%,?2=2.588,P=0.108). No hemorrhage was observed at 24 hours in both the groups. No significantly difference was noticed in the injection volume between the two groups [(11.0?6.0) ml (5-30 ml) in hemocoagulase group vs. (11.9?7.0) ml (5-28 ml); t=-0.535,P=0.595]. In epinephrine group,the mean artery blood pressure and heart rate increased significantly after the injection [(96.9?7.9) mm Hg vs. (99.9?8.1) mm Hg,t=-3.005,P=0.005; 79.8?7.9/min vs. 84.3?8.1/min,t=-3.585,P=0.001]. Whereas,no such differences were noticed in hemocoagulase group. Five cases in epinephrine group showed transient dizziness and palpitation,and 2 patients who had esophageal lesions complained of pain at the injection site. None of the hemocoagulase group had postoperative complications. Conclusions Hemocoagulase shows same anti-hemorrhage effect as epinephrine during EMR without leading to adverse effect.
3.Characteristics and tendencies of Bundeswehr's field medical equipment in 21st Century
Shutian GAO ; Yundou WANG ; Ruixing LI
Chinese Medical Equipment Journal 2003;0(10):-
The dominant position of Bundeswehr makes its field medical equipment representative in European troops.With a history more than 50 years,Bundeswehr's field medical equipment passes through 4 phases and has evolved into a complete system,which adopts backpacks,chests,vehicles and containers as the main carrier to adapt to different requirements of field medical service.Bundeswehr's field medical equipment is gifted with such tendencis as high mobility and informatization level.
4.The effect of different doses of simethicone on colonoscopy bowel preparation
Haiyan TAO ; Peng LI ; Shutian ZHANG
Chinese Journal of Digestive Endoscopy 2014;31(10):579-582
Objective To observe the clinical effect of different doses of simethicone on the colonoscopy bowel preparation.Methods One hundred and fifty outpatients who received colonoscopy were randomly divided into three groups:group A1 (PEG plus 5 ml simethicone),group A2 (PEG plus 10 ml simethicone) and group B (PEG =polyethylene glycol electrolyte).The colonic cleaness,effect of removing bubbles,total procedure time,patients' satisfaction and tolerance were observed during the examination.Results The satisfaction with bubbles removal were 98.0% (49/50),100.0% (50/50) and 80.0% (40/50) with significant difference(x2 =17.855,P =0.000).However,there was no difference in cleaness (x2 =1.500,P =0.472),total procedure time (Z =-0.333,P =0.765),patients' satisfaction (x2 =6.303,P =0.178) and tolerance (x2 =8.238,P =0.083).Conclusion Simethicone is of benefit for colonoscopic bowel preparation in removing air bubbles,which can enhance visibility.Five ml dose of simethicone can meet the basic need of removing air bubbles,and 10 ml dose of simethicone can exert better effects.
5.Endoscopic retrograde cholangiopancreatography by using carbon dioxide for malignant biliary obstruction
Wei LI ; Ming JI ; Yongjun WANG ; Peng LI ; Shutian ZHANG
Chinese Journal of Digestive Endoscopy 2010;27(10):509-512
Objective To explore the safety and efficacy of endoscopic retrograde cholangiopancreatography(ERCP)by using carbon dioxide for malignant biliary obstruction.Methods A total of 60 patients with malignant biliary obstruction, hospitalized from September 2008 to February 2010, were randomly divided into 3 groups to receive ERCP by using carbon dioxide, contrast agent or magnetic resonance cholangiopancreatography(MRCP)without any agent.The safety and efficacy of 3 contrast methods were compared.Results Successful stent or drainage tube insertion was achieved in all patients.Carbon dioxide was superior to contrast agent in terms of lowering postoperative infection rate(P < 0.05), and it was also superior to MRCP for more effective drainage(P < 0.05).There was no significant difference in occurrence of postoperative pancreatitis and hyperamylasemia between 3 groups.Conclusion Using carbon dioxide during ERCP, safe and effective, is superior to use of contrast agent in less leukocyte increase, and to MRCP in more adequate drainage in patients with malignant biliary obstruction.Furthermore, there is no more risk of pancreatitis and hyperamylasemia.
6.In vitro oxalate-degrading ability of 10 strains of lactic acid bacteria for yoghourt fermentation
Shutian ZHAO ; Shiqing ZHANG ; Xin GU ; Jiantao LI
Journal of Shanghai Jiaotong University(Medical Science) 2009;29(12):1463-1466
Objective To investigate the oxalate-degrading abilities of 10 strains of lactic acid bacteria for yoghourt fermentation. Methods Ten different strains of lactic acid bacteria (L.acidophilus, L.paracasei, Enterococcaceae faecium, B. lactis, B. adolescentis, B. infantis, B.longum, Lactococcus lactis subsp. Cremori, L.bulgaricus and S. thermophilus) were cultured separately in culture fluid containing 5 mmol/L oxalate. Seventy-two hours after culture, the concentrations of oxalate and lactic acid bacteria were detected. Besides, blank control cultured without lactic acid bacteria was established. Results Seventy-two hours after culture, the concentrations of all the 10 strains of lactic acid bacteria were significantly higher than those before culture (P<0.01). Compared with blank control, the concentrations of oxalate in the culture fluid with 10 strains of lactic acid bacteria decreased 72 h after culture, and were significantly different from those before culture for L.acidophilus, Lactococcus lactis subsp. Cremori, B.longum, B. adolescentis and B. lactis (P<0.05 or P<0.01). The oxalate-degrading rate of B. lactis was the highest (29.03%), and that of Enterococcaceae faecium was the lowest (0.23%). The correlation analysis revealed that there was no significant correlation between times of proliferation and oxalate-degrading rates (r=0.435 7, P=0.208 2). Conclusion All of the 10 strains of lactic acid bacteria for yoghourt fermentation have the ability of oxalate degrading, and there is no correlation between lactic acid bacteria proliferation and oxalate degradation.
7.Effects of kidney calcium oxalate calculus resistant acidophilus milk versus commercially available sacidophilus milk on urinary oxalate excretion in rats
Shutian ZHAO ; Shiqing ZHANG ; Xin GU ; Jiantao LI
Journal of Shanghai Jiaotong University(Medical Science) 2009;29(12):1467-1470
Objective To compare the effects of kidney calcium oxalate calculus resistant acidophilus milk (KCOCRAM) versus commercially available acidophilus milk (CAAM) on urinary oxalate excretion in rats. Methods Fifty SD rats were randomly divided into 5 groups (n=10), and were bred with KCOCRAM (KCOCRAM group), CAAM (CAAM group), sterilized KCOCRAM (sterilized KCOCRAM group), sterilized CAAM (sterilized CAAM group) and water (blank control group), respectively for a consecutive 20 d, with 4 mL/d for each rat. The data of body weight and 24 h urinary oxalate excretion volume were obtained 1 d before breeding and every 4 d during breeding. Results During breeding, body weight and 24 h urinary oxalate excretion volume of each group increased with time. There was no significant difference in urinary oxalate excretion volume among sterilized KCOCRAM group, sterilized CAAM group and blank control group (P>0.05). The increase tendency of KCOCRAM group and CAAM group was weaker than that of the other three groups. The urinary oxalate excretion volume was significantly lower in KCOCRAM group than that in sterilized KCOCRAM group from 8 d after breeding, and that was significantly lower in CAAM group than that in sterilized CAAM group from 12 d after breeding (P<0.05). The urinary oxalate excretion volume was significantly lower in KCOCRAM group than that in CAAM group from 16 d after breeding (P<0.05). There was a positive correlationship between body weight and 24 h urinary oxalate excretion volume in each group (r=0.97-0.99, P<0.01). Conclusion Both KCOCRAM and CAAM can reduce urinary oxalate excretion in rats, and the former has a more favourable effect.
8.Endoscopic mucosal resection for rectal carcinoid tumors
Ye ZONG ; Ming JI ; Li YU ; Yinglin NIU ; Shutian ZHANG
Chinese Journal of Digestive Endoscopy 2010;27(7):353-355
Objective To evaluate the efficacy and safety of endoscopic mucosal resection (EMR) for rectal carcinoid tumors. Methods From January 2006 to January 2009, EMR was performed in 28 patients with rectal carcinoids, who were followed up to evaluate the therapeutic effect and safety. Results Tumor diameters varied from 0.4 cm to 1. 2 cm (mean 0.7± 0. 2 cm). Negative resection margin was a-chieved in 26 cases (92. 9% ), tumor margin within 0. 1 cm of resection margin in 1 (7. 1% ) , and two margins coincided in 1 patient (7. 1% ). Hemostasis was performed with metal clips in 14 patients (50% ) and argon plasma coagulation (APC) in 9 (32. 1% ). Except for rectal bleeding in 1 patient (3. 6% ) , no other complications were observed. There was no recurrence in any patients during a follow-up of 6-36 months. Conclusion EMR is a useful and safe method for treatment of small rectal carcinoid tumor which does not cross submucosal layer.
9.The diagnostic value of intraductal ultrasonography for complex biliary and pancreatic disease
Li ZHAO ; Shutian ZHANG ; Ming JI ; Bingqi CHEN
Chinese Journal of Internal Medicine 2009;48(8):625-628
.7%and 88.6%.Conclusion IDUS after ERCP yields higher diagnostic accuracy for complex biliary and pancreatic diseases and it is also more dependable in differentiating benign tissues from malignant ones than ERCP alones
10.Risk factors of early rebleeding after endoscopic variceal ligation and/or endoscopic injection of fibrin tissue adhesive
Wenyan LIANG ; Peng LI ; Ming JI ; Shutian ZHANG
Chinese Journal of Digestive Endoscopy 2012;29(10):541-544
Objective To study the independent risk factors of early rebleeding after endoscopic variceal ligation (EVL) and/or endoscopic injection of fibrin tissue adhesive.Methods Data of 370 patients who had cirrhosis and accepted 396 procedures of EVL and/or endoscopic injection of fibrin tissue adhesive were retrospectively studied.Independent risk factors for early rebleeding were determined by Logistic regression analysis.Results Results of all the factors that were significantly different between the re-bleeding and non-rebleeding patients,the portal vein diameter,ascites volume,Child-Pugh score and serum albumin were independent ones of early rebleeding after EVL and/or endoscopic injection of fibrin tissue adhesive ( P < 0.05).Larger volume of ascites,wider portal vein diameter,reduced albumin,Child-Pugh score greater than 10 were indicative factors of rebleeding.Conclusion The early rebleeding rate after EVL and/or endoscopic injection of fibrin tissue adhesive is determined by portal vein diameter,ascites volume,ChildPugh score,and serum albumin.