1. The ultrastructure of the synapses in the supraoptic nucleus of the hypothalamus of the rat has been studied with the electron microscope after fixation by glutaraldehyde-osmium tetroxide and double staining with urayl acetate and lead citrate.2. It was found that the morphological features of the synaptic vesicle are closely related to those of the smooth endoplasmic reticulum of the axonal endings.3. On the basis of the facts that the size, form, distribution and arrangement of the synaptic vesicles are similar to the endoplasmic reticulum, it was assumed that both organoids are homologous structures.4. The synaptic vesicles may be mainly derived from the endoplasmic reticulum in tile axonal endings. An other possible way of their may be from the invagination of the surface membrane of the eudings.

The submicroscopic structure of the postsynaptic membrane and the snbsynaptic dense body in the supraoptic nucleus of the hypothalamus of rat were studied. It was found that the subsynaptic dense body and postsynaptic membrane were connected by fine filaments. The subsynaptic dense body was closely related to the postsynaptic membrane and its submicroscopic configuration was complicated. In spite of the obvious differences existing between the subsynaptic dense bodies, nevertheless a typical one was described in this nucleus.It is of interest to note that most subsynaptic dense bodies were mainly encountered within the postsynaptic element of Gray's Type Ⅰ synapse, thus the authors postulated that the subsynaptic dense body would play an important role in the excitatory synapse.

Objective To study the relationship between the serum selenium(Se) concentra- tion and glutathione peroxidase(GSH-PX) levels in red blood cell in patients with pregnancy induced hypertension(PIH).Methods The serum Se concentration was measured by atomic absorbability assay and the GSH-PX levels were measured by cellular chemiluminescence assay.49 cases of PIH and 34 normal pregnant women were measured for serum Se concentration and GSH-PX levels in red blood cell from April,1994 to December,1994.Results The serum Se concentration and GSH-PX levels in red blood cell is different betwen PIH and control group.Compared serum Se concentration and GSH-PX levels were significant lower in the PIH patients than in the control subjects (P

To introduce a rehabilitation program for total hip replacement (THR), including muscle strength training; rehabilitation for scar and adhesion, scoliosis, hip control, etc. The principle and the cautions were discussed.

To introduce tutorial system for undergraduate in the forensic biology teaching is an important measure of educational reform of forensic medicine.The article presented some schemes and experiences about the practice of tutorial system for undergraduate in the forensic biology department of Kunming Medical College.

Objective To evaluate the effectiveness and safety of triptorelin in the treatment of uterine leiomyoma. Methods A multi-center, prospective, randomly controlled clinical trial was carried out from Dec. 2002 to Mar. 2004 in three university hospitals. A total of 125 qualified patients with uterine leiomyoma were randomly divided into either triptorelin group (63 cases) treated with 3.75 mg triptorelin injected intramuscularly or leuprorelin group (62 cases) treated with 3.75 mg leuprorelin injected subcutaneously. Both drugs were injected every 28 days for a total of 3 months. Results All 125 patients finished the trial. The uterine volumes were similar before treatment between the triptorelin group and the leuprorelin group and were decreased significantly after drug therapy (P0.05).) The volumes of the largest leiomyoma decreased significantly after drug therapy (P0.05). Patients with serum level of 17?-estradiol 0.05). Dysmenorrhea, noncyclic pelvic pain and pressure-like symptoms were relieved quickly and remarkably in both groups after treatment. The rates of adverse event occurred in 71% of patients in both groups. The main side effects included flare-up effects and hypoestrogenic symptoms. Nine patients in the triptorelin group and 6 in the leuprorelin group received add-back therapy with tibolone 1.25-2.50 mg/d because of remarkable climacteric-like symptoms. Conclusion Treatment of uterine leiomyoma with triptorelin for 3 months is both effective and safe in Chinese women.

Objective To study the D gene polymorphism of Rh-negative blood group in Kunming resident population with PCR technology for gene typing,and to establish and perfect PCR detecting method for RhD gene.Method 46 samples of Rh-negative blood samples were collected and PCR amplification with exon-SSP had been done firstly.The samples of D gene part existing were screened,then PCR amplifying by intron-SSP had been conducted.The PCR amplification production with intron-SSP was used to DNA sequence.Results Among 46 Rh-negative samples,the number of D gene lost intacfly was 29;the complete existing one with all exons was 12.The sequencing results were that 2 samples of only containing D10 were RhD-CE(3-9)-D and the sample with only D4 and D6 was the newly discovered variant allele RhD-CE(2-3,5,7-9)-D.RhD ? was not found in our study.Conclusion(1)There is high frequency of RhD-CE(3-9)-D in Kunming area.(2)A new variant allele of RhD-CE(2-3,5,7-9)-D is first found in Kunming area.

Forensic biology is a main subject of forensic medicine.With the rapid development of science and technology,the courses should be constantly improved.New teaching mode has come into being application of multimedia technology in theoretical lessons,case teaching,independent completion of experimental lessons,which is thanks to the constant reinforcement of teaching staff and the reform of course content and teaching methods.

The article elaborated the standard of quality control,open service management system and requirements for system construction of forensic biology laboratory,which is to share laboratory recourses and advance the healthy and sustainable development of the laboratory.